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Xenobiotica
the fate of foreign compounds in biological systems
Volume 12, 1982 - Issue 1
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Research Article

Hepatic microsomal metabolism and macromolecular binding of the antioxidant, n-phenyl-2-naphthylamine

M. M. Anderson National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas 72079, USA
,
R. K. Mitchum National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas 72079, USA
&
F. A. Beland National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas 72079, USA
Pages 31-43 | Received 06 Jul 1981, Published online: 22 Sep 2008

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Tobias Weiss, Thomas Brüning & Hermann M. Bolt. (2007) Dephenylation of the Rubber Chemical N-Phenyl-2-Naphthylamine to Carcinogenic 2-Naphthylamine: A Classical Problem Revisited. Critical Reviews in Toxicology 37:7, pages 553-566.
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M. J. Galmier, J. F. Pognat, C. Lartigue-Mattei, J. L. Chabard, M. Bastide, N. Busch & J. A. Berger. (1991) Biotransformation study of para-substituted phenylpiperazines in Beagle dogs by gas chromatography-mass spectrometry. Xenobiotica 21:10, pages 1371-1384.
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Rex E. Hornish, S. Ron, Jean M. Nappier & E. Gosline. (1987) Comparative Metabolism of Lincomycin in the Swine Chicken, and Cat. Drug Metabolism Reviews 18:2-3, pages 177-214.
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Souheil Laham & Marc Potvin. (1983) Biological Conversion of N-Phenyl-2-Naphthylamine to 2-Naphthylamine in the Sprague-Dawley Rat. Drug and Chemical Toxicology 6:3, pages 295-309.
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Articles from other publishers (9)

Hanwen Chang, Yongbao Xu, Lingshan Lv, Huiling Liu, Qifeng Wang & Xuri Huang. (2019) Computational study on C1- versus C3-regioselectivity in Pd(II)-catalyzed olefination/dearomatization of 2-naphthyl ureas. Molecular Catalysis 477, pages 110540.
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Tobias Weiss, Hermann M. Bolt, Gerhard Schlüter, Stephan Koslitz, Dirk Taeger, Peter Welge & Thomas Brüning. (2013) Metabolic dephenylation of the rubber antioxidant N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine in rats. Archives of Toxicology 87:7, pages 1265-1272.
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Rolf Altenburger, Werner Brack, William R. Greco, Matthias Grote, Klaus Jung, Agnes Ovari, Janet Riedl, Katrin Schwab & Eberhard Küster. (2006) On the Mode of Action of N -Phenyl-2-naphthylamine in Plants . Environmental Science & Technology 40:19, pages 6163-6169.
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A. Enreille, J. F. Pognat, M. J. Galmter, C. Larttgue-Mattei, J. L. Chabard, N. Busch & J. A. Berger. (1991) N-Dephenylated and N-phenyl urinary metabolites of mociprazine (CERM 3517) in beagle dogs after oral administration. A mass spectrometric determination. European Journal of Drug Metabolism and Pharmacokinetics 16:2, pages 161-172.
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Thomas A. Baillie & Albert W. Rettenmeier. (1986) Drug Biotransformation: Mechanistic Studies With Stable Isotopes. The Journal of Clinical Pharmacology 26:6, pages 448-451.
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A. L. Burlingame, Joanne O. Whitney & David H. Russell. (2002) Mass spectrometry. Analytical Chemistry 56:5, pages 417-467.
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Giovanni Carlucci, Luisa Airoldi, Roberto Fanelli & Biagio Laguzzi. (1984) Quantitative analysis of aromatic amines in human urine by gas chromatography—mass spectrometry—selected-ion monitoring. Journal of Chromatography B: Biomedical Sciences and Applications 311, pages 141-147.
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Thomas A. Baillie, Albert W. Rettenmeier, Lisa A. Peterson & Neal CastagnoliJr.Jr.. 1984. 273 282 .
Souheil Laham & Marc Potvin. (1984) Comparative N-dephenylation of N-phenyl-2-naphthylamine in Sprague-Dawley rats and New Zealand White rabbits. Chemosphere 13:5-6, pages 657-667.
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