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Xenobiotica
the fate of foreign compounds in biological systems
Volume 12, 1982 - Issue 4
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Research Article

Metabolism of tiaramide in vitro: I. Oxidative metabolism of tiaramide by human and rat liver microsomes

K. Iwasaki Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., 1–6, Kashima-2-chome, Yodogawa-ku, Osaka, 532, Japan
,
H. Noguchi Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., 1–6, Kashima-2-chome, Yodogawa-ku, Osaka, 532, Japan
,
T. Kamataki Department of Pharmacology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160, Japan
&
R. Kato Department of Pharmacology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160, Japan
Pages 221-226 | Received 01 Nov 1981, Published online: 22 Sep 2008

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Read on this site (4)

Garth Powis. (1989) The Use of Human Liver for Foreign Compound Metabolism and Toxicity Studies. Drug Metabolism Reviews 20:2-4, pages 379-394.
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K. Iwasaki, T. Shiraga, K. Noda, K. Tada & H. Noguchi. (1983) Terminal N-sulphoconjugation of an alicyclic amine (piperazine), identified as a new metabolite of tiaramide in mouse and rat. Xenobiotica 13:5, pages 273-278.
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H. Noguchi, K. Tada & K. Iwasaki. (1982) Urinary metabolite profile of tiaramide in man and in some animal species. Xenobiotica 12:4, pages 211-220.
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H. Noguchi & K. Iwasaki. (1982) Metabolism of tiaramide in vitro II. Oxidation of piperazineethanol group in tiaramide by 105 000 g supernatants from monkey and rat liver. Xenobiotica 12:8, pages 499-508.
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Articles from other publishers (3)

Shufeng Zhou. 2016. Cytochrome P450 2D6. Cytochrome P450 2D6 139 288 .
R. Scott Obach. 2014. Handbook of Metabolic Pathways of Xenobiotics. Handbook of Metabolic Pathways of Xenobiotics 1 41 .
B. Clement. (1989) STRUCTURAL REQUIREMENTS OF MICROSOMAL N-OXYGENATIONS DERIVED FROM STUDIES ON AMIDINES. Drug Metabolism and Drug Interactions 7:1.
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