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Xenobiotica
the fate of foreign compounds in biological systems
Volume 12, 1982 - Issue 7
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Research Article

Xenobiotic cholesteryl ester formation

R. Fears Beecham Pharmaceuticals Research Division, Great Burgh, Epsom, Surrey, KT18 5XQ, UK
,
K. H. Baggaley Beecham Pharmaceuticals Research Division, Great Burgh, Epsom, Surrey, KT18 5XQ, UK
,
P. Walker Beecham Pharmaceuticals Research Division, Great Burgh, Epsom, Surrey, KT18 5XQ, UK
&
R. M. Hindley Beecham Pharmaceuticals Research Division, Great Burgh, Epsom, Surrey, KT18 5XQ, UK
Pages 427-433 | Received 17 Feb 1982, Published online: 22 Sep 2008

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Hideo Kaneko, Yasuko Takamatsu, Yasuyoshi Okuno, Junko Abiko, Akira Yoshitake & Junshi Miyamoto. (1988) Substrate specificity for formation of cholesterol ester conjugates from fenvalerate analogues and for granuloma formation. Xenobiotica 18:1, pages 11-19.
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Franz-Josef Leinweber. (1987) Possible Physiological Roles of Carboxylic Ester Hydrolases. Drug Metabolism Reviews 18:4, pages 379-439.
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Ellen M. Faed. (1984) Properties of Acyl Glucuronides: Implications for Studies of the Pharmacokinetics and Metabolism of Acidic Drugs. Drug Metabolism Reviews 15:5-6, pages 1213-1249.
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P. O. Gunnarsson, S. Å. Johansson & L. Svensson. (1984) Cholesterol ester formation by transesterification of chlorambucil: A novel pathway in drug metabolism. Xenobiotica 14:7, pages 569-574.
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Articles from other publishers (17)

Lars Weidolf & Ian Wilson. (2023) Minimizing the DILI potential of carboxylic acid-containing drugs: a perspective. Medicinal Chemistry Research.
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Ulrike Glaenzel, Yi Jin, Robert Nufer, Wenkui Li, Kirsten Schroer, Sylvie Adam-Stitah, Sjoerd Peter van Marle, Eric Legangneux, Hubert Borell, Alexander D. James, Axel Meissner, Gian Camenisch & Anne Gardin. (2018) Metabolism and Disposition of Siponimod, a Novel Selective S1P 1 /S1P 5 Agonist, in Healthy Volunteers and In Vitro Identification of Human Cytochrome P450 Enzymes Involved in Its Oxidative Metabolism . Drug Metabolism and Disposition 46:7, pages 1001-1013.
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Richard B. Silverman & Mark W. Holladay. 2014. The Organic Chemistry of Drug Design and Drug Action. The Organic Chemistry of Drug Design and Drug Action 357 422 .
Andrew J Hutt & John Caldwell. (1983) The metabolic chiral inversion of 2-arylpropionic acids—a novel route with pharmacological consequences. Journal of Pharmacy and Pharmacology 35:11, pages 693-704.
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Bernard Testa & Stefanie D. Krämer. (2008) The Biochemistry of Drug Metabolism – An Introduction. Chemistry & Biodiversity 5:11, pages 2171-2336.
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Richard B. Silverman. 2004. The Organic Chemistry of Drug Design and Drug Action. The Organic Chemistry of Drug Design and Drug Action 405 495 .
B. Walther, P. Vis & A. Taylor. 1996. Lipophilicity in Drug Action and Toxicology. Lipophilicity in Drug Action and Toxicology 253 261 .
Peter F. Dodds. (1995) Xenobiotic lipids: The inclusion of xenobiotic compounds in pathways of lipid biosynthesis. Progress in Lipid Research 34:3, pages 219-247.
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Peter F. Dodds. (1991) Incorporation of xenobiotic carboxylic acids into lipids. Life Sciences 49:9, pages 629-649.
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Hari K. Bhat & G.A.S. Ansari. (1989) Chromatographic separation of cholesteryl acetate and its chloro analogues. Journal of Chromatography A 462, pages 467-470.
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G.D. Jones, C.D. Evans, V. Facchini & O.R.W. Lewellen. (1989) Determination of 2-n-octadecylindole-5-carboxylic acid in human plasma by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 497, pages 121-130.
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Hari K. Bhat & G. A. S. Ansari. (1989) Covalent interaction of chloroacetic and acetic acids with cholesterol. Journal of Biochemical Toxicology 4:3, pages 189-193.
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Rolf K. Berge, Erik Stensland, Asle Aarsland, Ghezai Tsegai, Harald Osmundsen, Niels Aarsæther & Dag Rune Gjellesvik. (1987) Induction of cytosolic clofibroyl-CoA hydrolase activity in liver of rats treated with clofibrate. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 918:1, pages 60-66.
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Junshi Miyamoto, Hideo Kaneko & Yasuko Takamatsu. (2006) Stereoselective formation of a cholesterol ester conjugate from fenvalerate by mouse microsomal carboxyesterase(s). Journal of Biochemical Toxicology 1:2, pages 79-93.
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Yasuyoshi Okuno, Takaki Seki, Seiichi Ito, Hideo Kaneko, Tomoyuki Watanabe, Tomoyuki Yamada & Junshi Miyamoto. (1986) Differential metabolism of fenvalerate and granuloma formation. Toxicology and Applied Pharmacology 83:1, pages 157-169.
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Hideo Kaneko, Masatoshi Matsuo & Junshi Miyamoto. (1986) Differential metabolism of fenvalerate and granuloma formation. Toxicology and Applied Pharmacology 83:1, pages 148-156.
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B. K. Bhat, M. Seth, A. P. Bhaduri, M. H. Bickel, Jürgen Drews, Fred Samson, J. Alejandro Donoso, D. L. Swallow, William J. Wechter, Barbara E. Loughman, G. B. West & Archie F. WilsonMarcel H. Bickel. 1984. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques 273 303 .

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