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Xenobiotica
the fate of foreign compounds in biological systems
Volume 13, 1983 - Issue 12
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Research Article

Metabolism of captopril-L-cysteine, a captopril metabolite, in rats and dogs

K. J. Kripalani Department of Drug Metabolism, The Squibb Institute for Medical Research, Princeton, NJ, 08540, USA
,
A. V. Dean Department of Drug Metabolism, The Squibb Institute for Medical Research, Princeton, NJ, 08540, USA
&
B. H. Migdalof Department of Drug Metabolism, The Squibb Institute for Medical Research, Princeton, NJ, 08540, USA
Pages 701-705 | Received 07 Apr 1983, Published online: 22 Sep 2008

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M. Nakaoka, W. Suzuki & H. Hakusui. (1990) Identification of a dithiol intermediate metabolite of malotilate in rats. Xenobiotica 20:1, pages 91-98.
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Articles from other publishers (9)

Jill C. M. Wait, Nimish Vaccharajani, James Mitroka, Mohammed Jemal, Sanaullah Khan, Samuel J. Bonacorsi, J. Kent Rinehart & Ramaswamy A. Iyer. (2006) METABOLISM OF [ 14 C]GEMOPATRILAT AFTER ORAL ADMINISTRATION TO RATS, DOGS, AND HUMANS . Drug Metabolism and Disposition 34:6, pages 961-970.
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Ramaswamy A. Iyer, Bimal Malhotra, Sanaullah Khan, James Mitroka, Samuel BonacorsiJr.Jr., Stephen C. Waller, J. Kent Rinehart & Kishin Kripalani. (2003) Comparative Biotransformation of Radiolabeled [ 14 C]Omapatrilat and Stable-labeled [ 13 C 2 ]Omapatrilat after Oral Administration to Rats, Dogs, and Humans . Drug Metabolism and Disposition 31:1, pages 67-75.
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Bimal K. Malhotra, Ramaswamy A. Iyer, Kathy M. Soucek, Douglas Behr, Wei‐chi Liao, James G. Mitroka, Sanjeev Kaul, Marvin B. Cohen & Catherine A. Knupp. (2013) Oral Bioavailability and Disposition of [ 14 C]Omapatrilat in Healthy Subjects . The Journal of Clinical Pharmacology 41:8, pages 833-841.
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X.H. Zhou & A. Li Wan Po. (1994) Stability and in vitro absorption of captopril, enalapril and lisinopril across the rat intestine. Biochemical Pharmacology 47:7, pages 1121-1126.
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Be-Sheng Kuo, James C. Poole, Kin-Kai Hwang & Haiyung Cheng. (1994) Determination of Bioavailability and Systemically Available Fractions of Drugs Undergoing Reversible Metabolism: Application to 4-Amino-5-chloro-2-[2- (methylsulfinyl)ethoxy]-/V-[2-(diethylamino)ethyl]benzamide and Its Sulfide and Sulfone Metabolites in Rats. Journal of Pharmaceutical Sciences 83:3, pages 386-390.
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Haiyung Cheng & William J. Jusko. (2006) Pharmacokinetics of reversible metabolic systems. Biopharmaceutics & Drug Disposition 14:9, pages 721-766.
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Haiyung Cheng & Linyee Shum. (2006) A method for calculating the mean absorption time of drugs undergoing reversible and first‐pass metabolism. Biopharmaceutics & Drug Disposition 14:1, pages 71-79.
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Haiyung Cheng & William J. Jusko. 1991. Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis. Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis 13 20 .
Olaf H. Drummer & Bevyn Jarrott. (2006) The disposition and metabolism of captopril. Medicinal Research Reviews 6:1, pages 75-97.
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