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Xenobiotica
the fate of foreign compounds in biological systems
Volume 13, 1983 - Issue 5
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Original Article

Terminal N-sulphoconjugation of an alicyclic amine (piperazine), identified as a new metabolite of tiaramide in mouse and rat

K. Iwasaki Research Laboratories, Fujisawa Pharmaceutical Co., Ltd, 1–6, Kashima-2-chome, Yodogawa-ku, Osaka, 532, Japan
,
T. Shiraga Research Laboratories, Fujisawa Pharmaceutical Co., Ltd, 1–6, Kashima-2-chome, Yodogawa-ku, Osaka, 532, Japan
,
K. Noda Research Laboratories, Fujisawa Pharmaceutical Co., Ltd, 1–6, Kashima-2-chome, Yodogawa-ku, Osaka, 532, Japan
,
K. Tada Research Laboratories, Fujisawa Pharmaceutical Co., Ltd, 1–6, Kashima-2-chome, Yodogawa-ku, Osaka, 532, Japan
&
H. Noguchi Research Laboratories, Fujisawa Pharmaceutical Co., Ltd, 1–6, Kashima-2-chome, Yodogawa-ku, Osaka, 532, Japan
Pages 273-278 | Received 25 Oct 1982, Published online: 30 Sep 2009

Citations (6)

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Read on this site (4)

T. Shiraga, K. Iwasaki, K. Takeshita, H. Matsuda, T. Niwa, Z. Tozuka, T. Hata & F. P. Guengerich. (1995) Species- and gender-related differences in amine, alcohol and phenol sulphoconjugations. Xenobiotica 25:10, pages 1063-1071.
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K. Iwasaki, T. Shiraga, K. Tada, K. Noda & H. Noguchi. (1986) Age- and sex-related changes in amine sulphoconjugations in Sprague-Dawley strain rats. Comparison with phenol and alcohol sulphoconjugations. Xenobiotica 16:8, pages 717-723.
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K. Iwasaki, T. Shiraga, K. Noda, K. Tada & H. Noguchi. (1986) N-Sulphoconjugation of alicyclic, alkyl- and aryl-amines in vivo and in vitro. Xenobiotica 16:7, pages 651-659.
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K. Iwasaki, T. Shiraga, K. Noda, K. Tada & H. Noguchi. (1983) Metabolism of tiaramide in vitro III. Sulphoconjugation of alicyclic amine and alcoholic hydroxyl group by hepatic 105 000 g supernatants. Xenobiotica 13:9, pages 565-574.
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Articles from other publishers (2)

Kazuhide Iwasaki, Yoji Tokuma, Kosei Noda & Hideyo Noguchi. (1994) Age- and sex-related changes of sulfotransferase activities in the rat. Chemico-Biological Interactions 92:1-3, pages 209-217.
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Gerard J. Mulder. (1986) Sex differences in drug conjugation and their consequences for drug toxicity. Sulfation, glucuronidation and gluthatione conjugation. Chemico-Biological Interactions 57:1, pages 1-15.
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