Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 13, 1983 - Issue 7
44
Views
55
CrossRef citations to date
0
Altmetric
Original Article

Identification of 1-hydroxypyrene as a major metabolite of pyrene in pig urine

, , , &
Pages 415-420 | Received 29 Jan 1983, Published online: 30 Sep 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

F. C. P. Law, J. X. Meng, Y. T. He & Y. C. Chui. (1994) Urinary and biliary metabolites of pyrene in rainbow trout (Oncorhynchus mykiss). Xenobiotica 24:3, pages 221-229.
Read now
ScottD. Keimig & DonaldP. Morgan. (1986) Urinary 1-Naphthol as a Biological Indicator of Naphthalene Exposure. Applied Industrial Hygiene 1:2, pages 61-65.
Read now

Articles from other publishers (51)

Tina Wigger, Albrecht Seidel & Uwe Karst. (2017) Electrochemistry coupled to (LC-)MS for the simulation of oxidative biotransformation reactions of PAHs. Chemosphere 176, pages 202-211.
Crossref
Li Wang, Yuan Zhao, Xianying Liu, Tao Huang, Yanan Wang, Hong Gao & Jianmin Ma. (2015) Cancer risk of petrochemical workers exposed to airborne PAHs in industrial Lanzhou City, China. Environmental Science and Pollution Research 22:24, pages 19793-19803.
Crossref
Manuela Ciarrocca, Maria Valeria Rosati, Francesco Tomei, Assuntina Capozzella, Giorgia Andreozzi, Gianfranco Tomei, Alessandro Bacaloni, Teodorico Casale, Jean Claude Andrè, Mario Fioravanti, Maria Fernanda Cuartas & Tiziana Caciari. (2013) Is urinary 1-hydroxypyrene a valid biomarker for exposure to air pollution in outdoor workers? A meta-analysis. Journal of Exposure Science & Environmental Epidemiology 24:1, pages 17-26.
Crossref
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 216 .
Joanna Jurewicz, Michał Radwan, Wojciech Sobala, Sławomir Brzeźnicki, Danuta Ligocka, Paweł Radwan, Michał Bochenek & Wojciech Hanke. (2013) Association between a biomarker of exposure to polycyclic aromatic hydrocarbons and semen quality. International Journal of Occupational Medicine and Environmental Health 26:5.
Crossref
Xue Li, Xiaowei Fang, Zhiqiang Yu, Guoying Sheng, Minghong Wu, Jiamo Fu & Huanwen Chen. (2013) Direct analysis of urinary 1-hydroxypyrene using extractive electrospray ionization ion trap tandem mass spectrometry. Analytical Methods 5:11, pages 2816.
Crossref
Frans Jongeneelen & Wil ten Berge. (2011) Simulation of urinary excretion of 1-hydroxypyrene in various scenarios of exposure to polycyclic aromatic hydrocarbons with a generic, cross-chemical predictive PBTK-model. International Archives of Occupational and Environmental Health 85:6, pages 689-702.
Crossref
Oksana Yosypchuk, Jiří Barek & Vlastimil Vyskočil. (2012) Determination of 1-hydroxypyrene in human urine by HPLC with electrochemical detection at a boron-doped diamond film electrode. Analytical and Bioanalytical Chemistry 404:3, pages 693-699.
Crossref
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 210 .
F. Jongeneelen & R.B.M. Anzion. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 151 169 .
F. Jongeneelen & R. B. M. Anzion. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 14 .
J. Lintelmann. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 19 .
J. Lintelmann. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 163 187 .
Hwan-Goo Kang & Sang-Hee Jeong. (2011) 1-OH-Pyrene and 3-OH-Phenanthrene in Urine Show Good Relationship with their Parent Polycyclic Aromatic Hydrocarbons in Muscle in Dairy Cattle. Toxicological Research 27:1, pages 15-18.
Crossref
Tae-Gyu Nam. (2011) Lipid Peroxidation and Its Toxicological Implications. Toxicological Research 27:1, pages 1-6.
Crossref
Yeh-Chung Chien & Chun-Ting Yeh. (2010) Amounts and proportion of administered pyrene dose excreted as urinary 1-hydroxypyrene after dietary exposure to polycyclic aromatic hydrocarbons. Archives of Toxicology 84:10, pages 767-776.
Crossref
K. C. Donnelly & Ziad S. Naufal. 2010. Principles and Practice of Mixtures Toxicology. Principles and Practice of Mixtures Toxicology 485 512 .
In-Kyu Han, Xiaoli Duan, Lin Zhang, Hongbiao Yang, George G Rhoads, Fusheng Wei & Junfeng Zhang. (2007) 1-Hydroxypyrene concentrations in first morning voids and 24-h composite urine: intra- and inter-individual comparisons. Journal of Exposure Science & Environmental Epidemiology 18:5, pages 477-485.
Crossref
Hwan Goo KangSang Hee JeongMyung Haing ChoJoon Hyoung Cho. (2007) Changes of biomarkers with oral exposure to benzo(a)pyrene, phenanthrene and pyrene in rats. Journal of Veterinary Science 8:4, pages 361.
Crossref
Akira Toriba & Kazuichi Hayakawa. (2007) Biomarkers of Exposure to Polycyclic Aromatic Hydrocarbons and Related Compounds. Journal of Health Science 53:6, pages 631-638.
Crossref
Ping-Chi Hsu, I-Yueh Chen, Chih-Hong Pan, Kuen-Yuh Wu, Min-Hsiung Pan, Jenq-Renn Chen, Cheng-Jung Chen, Guo-Ping Chang-Chien, Chang-Hung Hsu, Chiu-Shong Liu & Ming-Tsang Wu. (2005) Sperm DNA damage correlates with polycyclic aromatic hydrocarbons biomarker in coke-oven workers. International Archives of Occupational and Environmental Health 79:5, pages 349-356.
Crossref
Bjarne Styrishave, Kim Rewitz & Ole Andersen. (2004) Frequency of moulting by shore crabs Carcinus maenas (L.) changes their colour and their success in mating and physiological performance. Journal of Experimental Marine Biology and Ecology 313:2, pages 317-336.
Crossref
Anders M.B Giessing, Lawrence M Mayer & Thomas L Forbes. (2003) Synchronous fluorescence spectrometry of 1-hydroxypyrene: a rapid screening method for identification of PAH exposure in tissue from marine polychaetes. Marine Environmental Research 56:5, pages 599-615.
Crossref
Mette Sørensen, Herman Autrup, Peter Møller, Ole Hertel, Steen Solvang Jensen, Peter Vinzents, Lisbeth E. Knudsen & Steffen Loft. (2003) Linking exposure to environmental pollutants with biological effects. Mutation Research/Reviews in Mutation Research 544:2-3, pages 255-271.
Crossref
Anders Holm, Paal Molander, Elsa Lundanes, Steinar Øvrebø & Tyge Greibrokk. (2003) Fast and sensitive determination of urinary 1-hydroxypyrene by packed capillary column switching liquid chromatography coupled to micro-electrospray time-of-flight mass spectrometry. Journal of Chromatography B 794:1, pages 175-183.
Crossref
Anders M. B. Giessing, Lawrence M. Mayer & Thomas L. Forbes. (2003) 1-hydroxypyrene glucuronide as the major aqueous pyrene metabolite in tissue and gut fluid from the marine deposit-feeding polychaete Nereis diversicolor . Environmental Toxicology and Chemistry 22:5, pages 1107-1114.
Crossref
Jürgen Jacob & Albrecht Seidel. (2002) Biomonitoring of polycyclic aromatic hydrocarbons in human urine. Journal of Chromatography B 778:1-2, pages 31-47.
Crossref
Anders M. B. Giessing & Torben Lund. (2002) Identification of 1-hydroxypyrene glucuronide in tissue of marine polychaeteNereis diversicolor by liquid chromatography/ion trap multiple mass spectrometry. Rapid Communications in Mass Spectrometry 16:16, pages 1521-1525.
Crossref
St Ferrari, F Mandel & J.D Berset. (2002) Quantitative determination of 1-hydroxypyrene in bovine urine samples using high-performance liquid chromatography with fluorescence and mass spectrometric detection. Chemosphere 47:2, pages 173-182.
Crossref
Nathalie Grova, Cyril Feidt, Claire Laurent & Guido Rychen. (2002) Milk, urine and faeces excretion kinetics in lactating goats after an oral administration of aromatic hydrocarbons. International Dairy Journal 12:12, pages 1025-1031.
Crossref
P Strickland. (1999) Urinary 1-hydroxypyrene and other PAH metabolites as biomarkers of exposure to environmental PAH in air particulate matter. Toxicology Letters 108:2-3, pages 191-199.
Crossref
J P Arnould, A Pfohl-Leszkowicz, V Bach, J P Libert & J Belegaud. (2016) Biological monitoring exposure of workers from plant producing carbon electrodes: quantification of benzo[a]pyrene DNA adducts in leukocytes, by a 32P-postlabelling method and an immunoassay. Human & Experimental Toxicology 18:5, pages 314-321.
Crossref
Clyde Johnson & Arthur Greenberg. (1999) Extraction and high-performance liquid chromatographic separation of selected pyrene and benzo[a]pyrene sulfates and glucuronides: preliminary application to the analysis of smokers’ urine. Journal of Chromatography B: Biomedical Sciences and Applications 728:2, pages 209-216.
Crossref
Sami Haddad, Robert Tardif, James Withey & Kannan Krishnan. (1997) Rate of pyrene metabolism in rat liver post-mitochondrial fractions. Toxicology Letters 93:2-3, pages 177-184.
Crossref
S. M. RamasamyRobert J. HurtubiseAinsley Weston. (2016) Detection of 1-Hydroxypyrene as a Urine Biomarker of Human PAH Exposure Determined by Fluorescence and Solid-Matrix Luminescence Spectroscopy. Applied Spectroscopy 51:9, pages 1377-1383.
Crossref
P Strickland, D Kang & P Sithisarankul. (1996) Polycyclic aromatic hydrocarbon metabolites in urine as biomarkers of exposure and effect.. Environmental Health Perspectives 104:suppl 5, pages 927-932.
Crossref
D Kang, N Rothman, S H Cho, H S Lim, H J Kwon, S M Kim, B Schwartz & P T Strickland. (1995) Association of exposure to polycyclic aromatic hydrocarbons (estimated from job category) with concentration of 1-hydroxypyrene glucuronide in urine from workers at a steel plant.. Occupational and Environmental Medicine 52:9, pages 593-599.
Crossref
Bettina Lange, Stefan Kremer, Olov Sterner & Heidrun Anke. (1994) Pyrene Metabolism in Crinipellis stipitaria : Identification of trans -4,5-Dihydro-4,5-Dihydroxypyrene and 1-Pyrenylsulfate in Strain JK364 . Applied and Environmental Microbiology 60:10, pages 3602-3607.
Crossref
Edith L. C. Lin, Susan M. Cormier & Richard N. Racine. (2009) Synchronous fluorometric measurement of metabolites of polycyclic aromatic hydrocarbons in the bile of brown bullhead. Environmental Toxicology and Chemistry 13:5, pages 707-715.
Crossref
P J Boogaard & N J van Sittert. (1994) Exposure to polycyclic aromatic hydrocarbons in petrochemical industries by measurement of urinary 1-hydroxypyrene.. Occupational and Environmental Medicine 51:4, pages 250-258.
Crossref
G. Grimmer, G. Dettbarn & J. Jacob. (1993) Biomonitoring of polycyclic aromatic hydrocarbons in highly exposed coke plant workers by measurement of urinary phenanthrene and pyrene metabolites (phenols and dihydrodiols). International Archives of Occupational and Environmental Health 65:3, pages 189-199.
Crossref
Manuela Granella & Erminio Clonfero. (1992) Sensitivity of different bacterial assays in detecting mutagens in urine of humans exposed to polycyclic aromatic hydrocarbons. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 268:1, pages 131-137.
Crossref
T J Buckley & P J Lioy. (1992) An examination of the time course from human dietary exposure to polycyclic aromatic hydrocarbons to urinary elimination of 1-hydroxypyrene.. Occupational and Environmental Medicine 49:2, pages 113-124.
Crossref
F.J. Jongeneelen & R.P. Bos. (1990) Excretion of pyrene and hydroxypyrene in urine. Cancer Letters 51:2, pages 175-177.
Crossref
J. Jacob, H. Brune, G. Gettbarn, D. Grimmer, U. Heinrich, E. Mohtashamipur, K. Norpoth, F. Pott & R. Wenzel-Hartung. (1989) Urinary and faecal excretion of pyrene and hydroxypyrene by rats after oral, intraperitoneal, intratracheal or intrapulmonary application. Cancer Letters 46:1, pages 15-20.
Crossref
M A HeitkampJ P FreemanD W MillerC E Cerniglia. (1988) Pyrene degradation by a Mycobacterium sp.: identification of ring oxidation and ring fission products. Applied and Environmental Microbiology 54:10, pages 2556-2565.
Crossref
Jeffrey E. Keiser, Laura J. Prokuski & Voon S. Ong. (1988) An enzymatic method for the hydrolysis of urinary 1-naphthyl glucuronide. Bulletin of Environmental Contamination and Toxicology 41:2, pages 159-163.
Crossref
A. Gold, K. Jayaraj, R. Sangaiah & L.M. Ball. (1988) Porphinatoiron-mediated oxidation of polycyclic aromatic hydrocarbons. Chemico-Biological Interactions 68:1-2, pages 39-55.
Crossref
F.J. Jongeneelen, R.B.M. Anzion & P.Th. Henderson. (1987) Determination of hydroxylated metabolites of polycyclic aromatic hydrocarbons in urine. Journal of Chromatography B: Biomedical Sciences and Applications 413, pages 227-232.
Crossref
Carl E. Cerniglia, Daniel W. Kelly, James P. Freeman & Dwight W. Miller. (1986) Microbial metabolism of pyrene. Chemico-Biological Interactions 57:2, pages 203-216.
Crossref
F. J. Jongeneelen, R. B. M. Anzion, Ch.-M. Leijdekkers, R. P. Bos & P. Th. Henderson. (1985) 1-Hydroxypyrene in human urine after exposure to coal tar and a coal tar derived product. International Archives of Occupational and Environmental Health 57:1, pages 47-55.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.