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Xenobiotica
the fate of foreign compounds in biological systems
Volume 14, 1984 - Issue 4
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Original Article

The metabolic fate of [14C]oxaprotiline · HCl in man. I. Disposition and preliminary pharmacokinetics

W. Dieterle Research and Development Department, Pharmaceuticals Division, CIBA-GEIGY Ltd, Basle, Switzerland
,
J. W. Faigle Research and Development Department, Pharmaceuticals Division, CIBA-GEIGY Ltd, Basle, Switzerland
,
P. Imhof Research and Development Department, Pharmaceuticals Division, CIBA-GEIGY Ltd, Basle, Switzerland
,
M. Sulc Research and Development Department, Pharmaceuticals Division, CIBA-GEIGY Ltd, Basle, Switzerland
&
J. Wagner Research and Development Department, Pharmaceuticals Division, CIBA-GEIGY Ltd, Basle, Switzerland
Pages 303-310 | Received 16 Jun 1983, Published online: 30 Sep 2009

Citations (6)

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Read on this site (2)

W. Dieterle, J. W. Faigle, H.-P. Kriemler & T. Winkler. (1986) Biotransformation of oxaprotiline: isolation and identification of metabolites in urine of rat and dog. Xenobiotica 16:8, pages 743-752.
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W. Dieterle, J. W. Faigle, W. Küng & W. Theobald. (1986) The disposition and metabolism of 14C-oxprenolol·HCl in man. Xenobiotica 16:2, pages 181-191.
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Articles from other publishers (4)

G. Kaiser, R. Ackermann, W. Dieterle, I. W. Reimann & P. R. Bieck. (2006) Pharmacokinetics of the antidepressant levoprotiline after intravenous and peroral administration in healthy volunteers. Biopharmaceutics & Drug Disposition 13:2, pages 83-93.
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R. Ackermann, G. Kaiser, F. Schueller & W. Dieterle. (1991) Determination of the antidepressant levoprotiline and itsN-desmethyl metabolite in biological fluids by gas chromatography/mass spectrometry. Biological Mass Spectrometry 20:11, pages 709-716.
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Tammo Winkler, Walter Dieterle, Paul Hung, Grety Rihs & Hans‐Peter Kriemler. (2004) The Structure of Diastereomeric Oxaprotiline Metabolites. An NMR Study. Helvetica Chimica Acta 67:8, pages 2082-2086.
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W. Dieterle, J. W. Faigle, W. Küng & W. Theobald. (2006) The metabolic fate of 14 C‐oxaprotiline · HCl in man. III. Stereospecific disposition . Biopharmaceutics & Drug Disposition 5:4, pages 377-386.
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