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Xenobiotica
the fate of foreign compounds in biological systems
Volume 14, 1984 - Issue 7
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Original Article

Role of UDPGA flux in acetaminophen clearance and hepatotoxicity

Veronica F. Price Department of Pharmacology, Medical University of South Carolina, Charleston, South Carolina, 29425, USA
&
D. J. Jollow Department of Pharmacology, Medical University of South Carolina, Charleston, South Carolina, 29425, USA
Pages 553-559 | Received 28 Nov 1983, Accepted 08 Mar 1984, Published online: 30 Sep 2009

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T. Wang, K. Shankar, M. J. Ronis & H. M. Mehendale. (2007) Mechanisms and Outcomes of Drug- and Toxicant-Induced Liver Toxicity in Diabetes. Critical Reviews in Toxicology 37:5, pages 413-459.
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Mack C. Mitchell, Reta Hamilton, Laura Wacker & Robert A. Branch. (1989) Zonal Distribution of Paracetamol Glucuronidation in the Isolated Perfused Rat Liver. Xenobiotica 19:4, pages 389-400.
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Articles from other publishers (18)

Q. Sun, T. W. Harper, E. A. Dierks, L. Zhang, S. Chang, A. D. Rodrigues & P. Marathe. (2011) 1-Aminobenzotriazole, a Known Cytochrome P450 Inhibitor, Is a Substrate and Inhibitor of N -Acetyltransferase . Drug Metabolism and Disposition 39:9, pages 1674-1679.
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Lars Loumann Knudsen. (2002) Ocular fluorophotometry in human subjects and in swine - with particular reference to long-term pharmacokinetics. Acta Ophthalmologica Scandinavica 80:s235, pages 1-24.
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James E. Heubi, Marguerite B. Barbacci & Hyman J. Zimmerman. (1998) Therapeutic misadventures with acetaminophen: Hepatoxicity after multiple doses in children. The Journal of Pediatrics 132:1, pages 22-27.
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K. S. Pang & M. Chiba. 1994. Pharmacokinetics of Drugs. Pharmacokinetics of Drugs 101 187 .
K. S. Pang & M. Chiba. 1994. Conjugation—Deconjugation Reactions in Drug Metabolism and Toxicity. Conjugation—Deconjugation Reactions in Drug Metabolism and Toxicity 257 309 .
Sonia M.F. de Morais, Susanna Y.M. Chow & Peter G. Wells. (1992) Biotransformation and toxicity of acetaminophen in congenic RHA rats with or without a hereditary deficiency in bilirubin UDP-glucuronosyltransferase. Toxicology and Applied Pharmacology 117:1, pages 81-87.
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Lars L. Knudsen, Thomas Olsen & Folmer Nielsen‐Kudsk. (2009) Long‐term kinetic vitreous fluorophotometry in normal and diabetic subjects. Acta Ophthalmologica 70:5, pages 570-577.
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M.H. Davies & R.C. Schnell. (1991) Oltipraz-induced amelioration of acetaminophen hepatotoxicity in hamsters. Toxicology and Applied Pharmacology 109:1, pages 29-40.
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John B. WatkinsIIIIII, Drew R. Engles & Lyle V. Beck. (1990) Effect of volatile anesthetics on the hepatic UDP-glucuronic acid pathway in mice. Biochemical Pharmacology 40:4, pages 731-735.
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Veronica F. Price & David J. Jollow. (1989) Effects of sulfur-amino acid-deficient diets on acetaminophen metabolism and hepatotoxicity in rats. Toxicology and Applied Pharmacology 101:2, pages 356-369.
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James H. Lewis & Hyman J. Zimmerman. (1989) Drug-induced Liver Disease. Medical Clinics of North America 73:4, pages 775-792.
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Veronica F. Price & David J. Jollow. (1989) Effect of glucose and gluconeogenic substrates on fasting-induced suppression of acetaminophen glucuronidation in the rat. Biochemical Pharmacology 38:2, pages 289-297.
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Veronica F. Price & David J. Jollow. (1988) Mechanism of decreased acetaminophen glucuronidation in the fasted rat. Biochemical Pharmacology 37:6, pages 1067-1075.
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Marla M. Reicks & John N. Hathcock. (1987) Effects of Methionine Deficiency and Ethanol Ingestion on Acetaminophen Metabolism in Mice. The Journal of Nutrition 117:3, pages 572-579.
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Veronica F. Price, Marion G. Miller & David J. Jollow. (1987) Mechanisms of fasting-induced potentiation of acetaminophen hepatotoxicity in the rat. Biochemical Pharmacology 36:4, pages 427-433.
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JAMES G. CONWAY, FREDRICK C. KAUFFMAN & RONALD G. THURMAN. 1987. The Isolated Hepatocyte. The Isolated Hepatocyte 21 49 .
Veronica F. Price & David J. Jollow. (1986) Strain differences in susceptibility of normal and diabetic rats to acetaminophen hepatotoxicity. Biochemical Pharmacology 35:4, pages 687-695.
Crossref
Veronica F. Price, Jennifer M. Schulte, Stephen M. Spaethe & David J. Jollow. 1986. Biological Reactive Intermediates III. Biological Reactive Intermediates III 697 706 .

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