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Xenobiotica
the fate of foreign compounds in biological systems
Volume 14, 1984 - Issue 7
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Original Article

Electrophilic metabolites of 3-methylindole as toxic intermediates in pulmonary oedema

M. R. Nocerini Department of Animal Sciences, Washington State University, Pullman, WA, 99164-6510, USA
,
J. R. Carlson Department of Animal Sciences, Washington State University, Pullman, WA, 99164-6510, USA
&
G. S. Yost College of Pharmacy, Washington State University, Pullman, WA, 99164-6510, USA
Pages 561-564 | Received 07 Nov 1983, Accepted 08 Mar 1984, Published online: 30 Sep 2009

Citations (10)

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Read on this site (2)

D. J. Smith, G. L. Skiles, M. L. Appleton, J. R. Carlson & G. S. Yost. (1993) Identification of goat and mouse urinary metabolites of the pneumotoxin, 3-methylindole. Xenobiotica 23:9, pages 1025-1044.
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M. J. Lynch, F. R. Mosher, W. R. Levesque & T. J. Newby. (1987) The in Vitro and in Vivo Metabolism of Morantel in Cattle and Toxicology Species. Drug Metabolism Reviews 18:2-3, pages 253-288.
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Articles from other publishers (8)

George E. Burrows & Ronald J. Tyrl. 2012. Toxic Plants of North America. Toxic Plants of North America 888 997 .
Amit S. Kalgutkar, Deepak Dalvie, R. Scott Obach & Dennis A. Smith. 2012. Reactive Drug Metabolites. Reactive Drug Metabolites 93 129 .
Hao Sun & Garold S. Yost. (2008) Metabolic Activation of a Novel 3-Substituted Indole-Containing TNF-α Inhibitor: Dehydrogenation and Inactivation of CYP3A4. Chemical Research in Toxicology 21:2, pages 374-385.
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Hao Sun, William J. Ehlhardt, Palaniappan Kulanthaivel, Diane L. Lanza, Christopher A. Reilly & Garold S. Yost. (2007) Dehydrogenation of Indoline by Cytochrome P450 Enzymes: A Novel “Aromatase” Process. Journal of Pharmacology and Experimental Therapeutics 322:2, pages 843-851.
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Jack Uetrecht & William Trager. 2007. Drug Metabolism. Drug Metabolism 145 166 .
Garold S. Yost, Mark R. Nocerini, James R. Carlson & Daniel J. Liberato. 1986. Biological Reactive Intermediates III. Biological Reactive Intermediates III 373 380 .
Mark R. Nocerini, James R. Carlson & Garold S. Yost. (1985) Adducts of 3-methylindole and glutathione: Species differences in organ-selective bioactivation. Toxicology Letters 28:2-3, pages 79-87.
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Gregory M. Becker, Mark R. Nocerini, James R. Carlson & Roger G. Breeze. (1985) Alkylation of bronchiolar epithelial cells by 3-methylindole metabolites in the horse. Toxicology Letters 24:1, pages 25-32.
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