Citations (35)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (16)
M. Walles, A. Pähler, E. M. Isin & L. Weidolf. (2022) Meeting report of the second European biotransformation workshop. Xenobiotica 52:4, pages 426-431.
Read now
Read now
T. TERAMURA*T. WATANABE, S. HIGUCHI & K. HASHIMOTO. (1997) Metabolism and pharmacokinetics of barnidipine hydrochloride, a calcium channel blocker, in man following oral administration of its sustained release formulation. Xenobiotica 27:2, pages 203-216.
Read now
Read now
T. TERAMURA*Y. FUKUNAGA, E. J. VAN HOOGDALEM, T. WATANABE & S. HIGUCHI. (1997) Examination of metabolic pathways and identification of human liver cytochrome P450 isozymes responsible for the metabolism of barnidipine, a calcium channel blocker. Xenobiotica 27:9, pages 885-900.
Read now
Read now
H. Nakabeppu, M. Asada, T. Oda, Y. Shinozaki & T. Yajima. (1996) Plasma and urinary metabolites of efonidipine hydrochloride in man. Xenobiotica 26:2, pages 229-239.
Read now
Read now
T. Teramura, T. Tokunaga, H. Matsumoto, T. Watanabe & S. Higuchi. (1996) Metabolism of barnidipine hydrochloride, a potent calcium antagonist, in rat and dog. Xenobiotica 26:2, pages 177-187.
Read now
Read now
N. Ogawa, K. Mizuno, K. Fukushima, T. Suwa & T. Satoh. (1993) Metabolic fate of a new dihydropyridine calcium antagonist, CD-349, in rat and dog. Xenobiotica 23:7, pages 747-759.
Read now
Read now
P. Grossi, M. Pellegatti, G. Vigelli, J. Ayrton, B. A. Duncan & J. Maltas. (1992) Lacidipine metabolism in rat and dog: identification and synthesis of main metabolites. Xenobiotica 22:8, pages 899-916.
Read now
Read now
U. G. Eriksson, K. J. Hoffmann, R. Simonsson & C. G. Regårdh. (1991) Pharmacokinetics of the enantiomers of felodipine in the dog after oral and intravenous administration of a pseudoracemic mixture. Xenobiotica 21:1, pages 75-84.
Read now
Read now
F. Takayama, Y. Iwasawa, K. Saito, K. Shiratori & M. Ohtawa. (1989) Metabolism of a new dihydropyridine calcium antagonist in rats and dogs. Xenobiotica 19:12, pages 1407-1420.
Read now
Read now
S. Terashita, Y. Tokuma, M. Sekiguchi & H. Noguchi. (1989) Sex differences in the metabolism and excretion of nilvadipine, a new dihydropyridine calcium antagonist, in rats. Xenobiotica 19:11, pages 1221-1229.
Read now
Read now
A. P. Beresford, P. V. Macrae & D. A. Stopher. (1988) Metabolism of amlodipine in the rat and the dog: A species difference. Xenobiotica 18:2, pages 169-182.
Read now
Read now
T. A. Sutfin, M. Gabrielsson & C. G. Regårdh. (1987) Effects of biliary excretion on the disposition of felodipine and metabolites in the rat. Xenobiotica 17:10, pages 1203-1214.
Read now
Read now
S. Terashita, Y. Tokuma, T. Fujiwara, Y. Shiokawa, K. Okumura & H. Noguchi. (1987) Metabolism of nilvadipine, a new dihydropyridine calcium antagonist, in rats and dogs. Xenobiotica 17:12, pages 1415-1425.
Read now
Read now
W. R. Rush, O. Alexander, D. J. Hall, L. Cairncross, R. J. Dow & D. J. G. Graham. (1986) The metabolism of nicardipine hydrochloride in healthy male volunteers. Xenobiotica 16:4, pages 341-349.
Read now
Read now
I. Midgley, L. F. Chasseaud, I. W. Taylor, L. M. Walmsley, A. G. Fowkes, A. Darragh, R. F. Lambe & R. Bonn. (1985) Metabolism and pharmacokinetics of the dihydropyridine calcium antagonist, ryosidine, in man. Xenobiotica 15:11, pages 965-977.
Read now
Read now
C. Bäärnhielm, I. Skånberg & K. O. Borg. (1984) Cytochrome P-450-dependent oxidation of felodipine—a 1,4-dihydropyridine—to the corresponding pyridine. Xenobiotica 14:9, pages 719-726.
Read now
Read now
Articles from other publishers (19)
Ragnar Thomsen, Henrik B. Rasmussen & Kristian Linnet. (2014) In Vitro Drug Metabolism by Human Carboxylesterase 1: Focus on Angiotensin-Converting Enzyme Inhibitors. Drug Metabolism and Disposition 42:1, pages 126-133.
Crossref
Crossref
Ruina Gao. 2014. Handbook of Metabolic Pathways of Xenobiotics. Handbook of Metabolic Pathways of Xenobiotics
1
5
.
Aki T. Heikkinen, Stephen Fowler, Lynn Gray, Jia Li, Ying Peng, Preeti Yadava, Aruna Railkar & Neil Parrott. (2013) In Vitro to in Vivo Extrapolation and Physiologically Based Modeling of Cytochrome P450 Mediated Metabolism in Beagle Dog Gut Wall and Liver. Molecular Pharmaceutics 10:4, pages 1388-1399.
Crossref
Crossref
J.L.C.M Dorne, K Walton & A.G Renwick. (2003) Human variability in CYP3A4 metabolism and CYP3A4-related uncertainty factors for risk assessment. Food and Chemical Toxicology 41:2, pages 201-224.
Crossref
Crossref
Toshiharu Sakai, Toshio Teramura, Hideaki Okamiya & Osamu Inagaki. (2007) A Review on Barnidipine: A Novel Calcium Antagonist. Cardiovascular Drug Reviews 15:4, pages 273-290.
Crossref
Crossref
Yumi Ohtake, Takashi Sakamoto, Ryota Nishioka, Kazuo Uno & Shigeru Tabata. (2012) Metabolic Fate of Felodipine in Man. Drug Investigation 4:6, pages 528-534.
Crossref
Crossref
Margareth Gabrielsson, Kurt-Jürgen Hoffmann & Carl Gunnar Regårdh. (1992) Determination of four carboxylic acid metabolites of felodipine in plasma by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 573:2, pages 265-274.
Crossref
Crossref
Ryota Nishioka, Isao Umeda, Naobumi Öi, Shigeru Tabata & Kazuo Uno. (1991) Determination of felodipine and its metabolites in plasma using capillary gas chromatography with electron-capture detection and their identification by gas chromatography—mass spectrometry. Journal of Chromatography B: Biomedical Sciences and Applications 565:1-2, pages 237-246.
Crossref
Crossref
T. A. Sutfin, T. Lind, M. Gabrielsson & C. G. Reg»rdh. (1990) Biliary secretion of felodipine metabolites in man after intravenous [14C]felodipine. European Journal of Clinical Pharmacology 38:5, pages 421-424.
Crossref
Crossref
F P Guengerich, L A Peterson & R H Böcker. (1988) Cytochrome P-450-catalyzed hydroxylation and carboxylic acid ester cleavage of Hantzsch pyridine esters.. Journal of Biological Chemistry 263:17, pages 8176-8183.
Crossref
Crossref
Ronald D. Smith, Peter S. Wolf, John R. Regan & Stanley R. JollyRonald D. Smith, Peter S. Wolf, John R. Regan & Stanley R. Jolly. 1988. The Emergence of Drugs which Block Calcium Entry. The Emergence of Drugs which Block Calcium Entry
115
152
.
A. G. Odynets, V. Ya. Parinov, A. A. Kimenis & G. Ya. Dubur. (1987) Study of the biotransformation of 1,4-dihydropyridines in experiments in vitro. Pharmaceutical Chemistry Journal 21:8, pages 551-554.
Crossref
Crossref
A. G. Odynets, B. Z. Simkhovich, A. A. Kimenis & G. Ya. Dubur. (1986) Pharmacological effects and mechanism of action for preparations of the 1,4-dihydropyridine series on the cardiovascular system (review). Pharmaceutical Chemistry Journal 20:12, pages 822-829.
Crossref
Crossref
C. Bäärnhielm, H. Dahlbäck & I. Skånberg. (2009)
In Vivo
Pharmacokinetics of Felodipine Predicted from
in Vitro
Studies in Rat, Dog and Man
. Acta Pharmacologica et Toxicologica 59:2, pages 113-122.
Crossref
Crossref
Catharina Bäärnhielm & Göran Hansson. (1986) Oxidation of 1,4-dihydropyridines by prostaglandin synthase and the peroxidic function of cytochrome P-450. Biochemical Pharmacology 35:9, pages 1419-1425.
Crossref
Crossref
Catharina Bäärnhielm*Christer Westerlund. (1986) Quantitative relationships between structure and microsomal oxidation rate of 1,4-dihydropyridines. Chemico-Biological Interactions 58, pages 277-288.
Crossref
Crossref
Sven-Olof Jansson. (1986) Characterization of drug purity by liquid chromatography. Journal of Pharmaceutical and Biomedical Analysis 4:5, pages 615-624.
Crossref
Crossref
Kurt-J. Hoffmann & Lars Weidolf. (1985) Identification of felodipine metabolites in rat urine. Biological Mass Spectrometry 12:8, pages 414-423.
Crossref
Crossref
Lars Weidolf. (1985) Bimodal column switching liquid chromatographic assay of six metabolites of [14C] felodipine in rat urine. Journal of Chromatography B: Biomedical Sciences and Applications 343, pages 85-97.
Crossref
Crossref