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Xenobiotica
the fate of foreign compounds in biological systems
Volume 14, 1984 - Issue 10
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Original Article

The interactions of hydrazine derivatives with rat-hepatic cytochrome P-450

S. J. Moloney Department of Biochemistry, The University of Texas Health Science Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX, 75235, USA
,
B. J. Snider Department of Biochemistry, The University of Texas Health Science Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX, 75235, USA
&
R. A. Prough Department of Biochemistry, The University of Texas Health Science Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX, 75235, USA
Pages 803-814 | Received 26 Jan 1984, Published online: 30 Sep 2009

Citations (23)

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Michael Murray. (1987) Mechanisms of the Inhibition of Cytochrome P 450-Mediated Drug Oxidation by Therapeutic Agents. Drug Metabolism Reviews 18:1, pages 55-81.
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Articles from other publishers (22)

M. Saeed Mirzaei, Maxim V. Ivanov, Avat Arman Taherpour & Saber Mirzaei. (2021) Mechanism-Based Inactivation of Cytochrome P450 Enzymes: Computational Insights. Chemical Research in Toxicology 34:4, pages 959-987.
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Maria Almira Correia & Paul. F. Hollenberg. 2015. Cytochrome P450. Cytochrome P450 177 259 .
Hajime Hirao, Pratanphorn Chuanprasit, Ying Yi Cheong & Xiaoqing Wang. (2013) How Is a Metabolic Intermediate Formed in the Mechanism‐Based Inactivation of Cytochrome P450 by Using 1,1‐Dimethylhydrazine: Hydrogen Abstraction or Nitrogen Oxidation?. Chemistry – A European Journal 19:23, pages 7361-7369.
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Peter Hlavica. (2006) Functional interaction of nitrogenous organic bases with cytochrome P450: A critical assessment and update of substrate features and predicted key active-site elements steering the access, binding, and orientation of amines. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1764:4, pages 645-670.
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Maria Almira Correia & Paul R. Ortiz de Montellano. 2005. Cytochrome P450. Cytochrome P450 247 322 .
Joo‐Youn Cho, Kyung‐Sang Yu, In‐Jin Jang, Byung‐Hwan Yang, Sang‐Goo Shin & Dong‐Seok Yim. (2002) Omeprazole hydroxylation is inhibited by a single dose of moclobemide in homozygotic EM genotype for CYP2C19. British Journal of Clinical Pharmacology 53:4, pages 393-397.
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Julia A Hasler, Ronald Estabrook, Michael Murray, Irina Pikuleva, Michael Waterman, Jorge Capdevila, Vijakumar Holla, Christian Helvig, John R Falck, Geoffrey Farrell, Laurence S Kaminsky, Simon D Spivack, Eric Boitier & Philippe Beaune. (1999) Human cytochromes P450. Molecular Aspects of Medicine 20:1-2, pages 1-137.
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Michael Murray. (2007) DRUG‐MEDIATED INACTIVATION OF CYTOCHROME P450. Clinical and Experimental Pharmacology and Physiology 24:7, pages 465-470.
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E. Albano, A. Comoglio, P. Clot, A. Iannone, A. Tomasi & M. Ingelman-Sundberg. (1995) Activation of alkylhydrazines to free radical intermediates by ethanol-inducible cytochrome P-4502E1 (CYP2E1). Biochimica et Biophysica Acta (BBA) - General Subjects 1243:3, pages 414-420.
Crossref
Paul R. Ortiz de Montellano & Maria Almira Correia. 1995. Cytochrome P450. Cytochrome P450 305 364 .
Preben Aagaard Nielsen, Ada Lagersted, Steffen Danielsen, Allan Astrup Jensen, Jim Hart & John C. Larsen. (1992) Mutagenic activity of nine N,N-disubstituted hydrazines in the Salmonella/mammalian microsome assay. Mutation Research/Genetic Toxicology 278:4, pages 215-226.
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Shosuke Kawanishi & Koji Yamamoto. (2002) Mechanism of site-specific DNA damage induced by methylhydrazines in the presence of copper(II) or manganese(III). Biochemistry 30:12, pages 3069-3075.
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P.M. Gannett, C. Garrett, T. Lawson & B. Toth. (1991) Chemical oxidation and metabolism of N-methyl-N-formylhydrazine. Evidence for diazenium and radical intermediates. Food and Chemical Toxicology 29:1, pages 49-56.
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Sylvia PARTHÉ & Wolfgang HAGMANN. (2005) Inhibition of leukotriene ω‐oxidation by isonicotinic acid hydrazide (isoniazid). European Journal of Biochemistry 187:1, pages 119-124.
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Johann M. van Zyl, Karen Basson, Reinhard A. Uebel & Ben J. van der Walt. (1989) Isoniazid-mediated irreversible inhibition of the myeloperoxidase antimicrobial system of the human neutrophil and the effect of thyronines. Biochemical Pharmacology 38:14, pages 2363-2373.
Crossref
Emanuele Albano, Aldo Tomasi, Lucia Goria-Gatti & Anna Iannone. (1989) Free radical activation of monomethyl and dimethyl hydrazines in isolated hepatocytes and liver microsomes. Free Radical Biology and Medicine 6:1, pages 3-8.
Crossref
E. Albano, A. Tomasi, A. Iannone, L. Goria-Gatti, V. Vannini & M. U. Dianzani. 1988. Eicosanoids, Lipid Peroxidation and Cancer. Eicosanoids, Lipid Peroxidation and Cancer 273 280 .
Emanuele Albano & Aldo Tomasi. (1987) Spin trapping of free radical intermediates produced during the metabolism of isoniazid and iproniazid in isolated hepatocytes. Biochemical Pharmacology 36:18, pages 2913-2920.
Crossref
Aldo Tomasi, Emanuele Albano, Barbara Botti & Vanio Vannini. (2016) Detection of Free Radical Intermediates in the Oxidative Metabolism of Carcinogenic Hydrazine Derivatives. Toxicologic Pathology 15:2, pages 178-183.
Crossref
Donald J. Tweedie, John M. Erikson & Russell A. Prough. (1987) Metabolism of hydrazine anti-cancer agents. Pharmacology & Therapeutics 34:1, pages 111-127.
Crossref
John M. Erikson & Russell A. Prough. (2006) Oxidative metabolism of some hydrazine derivatives by rat liver and lung tissue fractions. Journal of Biochemical Toxicology 1:1, pages 41-52.
Crossref
Paul R. Ortiz de Montellano & Norbert O. Reich. 1986. Cytochrome P-450. Cytochrome P-450 273 314 .

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