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Xenobiotica
the fate of foreign compounds in biological systems
Volume 14, 1984 - Issue 10
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Original Article

The site of reduction of sulphinpyrazone in the rabbit

H. A. Strong Clinical Pharmacology Group, University of Southampton, Bassett Crescent East, Southampton, SO9 3TU, UK
,
A. G. Renwick Clinical Pharmacology Group, University of Southampton, Bassett Crescent East, Southampton, SO9 3TU, UK
&
C. F. George Clinical Pharmacology Group, University of Southampton, Bassett Crescent East, Southampton, SO9 3TU, UK
Pages 815-826 | Received 27 Feb 1984, Published online: 30 Sep 2009

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Dong-Hyun Kim. (2023) Interaction of drugs with gut microbiota modulators. Drug Metabolism Reviews 55:3, pages 181-194.
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S.C. Mitchell & R.M. Nickson. (1993) Metabolism of Sulfur-Containing Xenobiotics. Sulfur reports 13:2, pages 161-189.
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H. A. Strong, A. G. Renwick, C. F. George, Y. F. Liu & M. J. Hill. (1987) The reduction of sulphinpyrazone and sulindac by intestinal bacteria. Xenobiotica 17:6, pages 685-696.
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Articles from other publishers (18)

Yukuang Guo, Hyunwoo Lee & Hyunyoung Jeong. 2020. The Microbiome in Health and Disease. The Microbiome in Health and Disease 61 93 .
Juan Antonio Gimenez-Bastida, Lucia Martinez Carreras, Angela Moya-Pérez & José Moisés Laparra Llopis. (2018) Pharmacological Efficacy/Toxicity of Drugs: A Comprehensive Update About the Dynamic Interplay of Microbes. Journal of Pharmaceutical Sciences 107:3, pages 778-784.
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. (2012) Scientific Opinion on Flavouring Group Evaluation 08, Revision 5 (FGE.08Rev5): Aliphatic and alicyclic mono‐, di‐, tri‐, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30. EFSA Journal 10:7.
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. (2012) Scientific Opinion on Flavouring Group Evaluation 08, Revision 4 (FGE.08Rev4): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30. EFSA Journal 10:2, pages 2455.
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. (2011) Scientific Opinion on Flavouring Group Evaluation 8, Revision 3 (FGE.08Rev3): Aliphatic and alicyclic mono‐, di‐, tri‐, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30. EFSA Journal 9:5.
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. (2010) Flavouring Group Evaluation 08 Rev2 (FGE.08 Rev2): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30. EFSA Journal 8:11, pages 1408.
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. (2010) Flavouring Group Evaluation 8, Revision 1 (FGE.08Rev1): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30. EFSA Journal 8:7, pages 1021.
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. (2009) Application (Reference EFSA‐GMO‐NL‐2008‐51) for the placing on the market of glyphosate tolerant genetically modified cotton GHB614, for food and feed uses, import and processing under Regulation (EC) No 1829/2003 from Bayer CropScience. EFSA Journal 7:3.
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S.C. Lee & A.G. Renwick. (1995) Sulphoxide reduction by rat intestinal flora and by Escherichia coli in vitro. Biochemical Pharmacology 49:11, pages 1567-1576.
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S.C. Lee & A.G. Renwick. (1995) Sulphoxide reduction by rat and rabbit tissues in vitro. Biochemical Pharmacology 49:11, pages 1557-1565.
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Haiyung Cheng & William J. Jusko. (2006) Pharmacokinetics of reversible metabolic systems. Biopharmaceutics & Drug Disposition 14:9, pages 721-766.
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M.Abu Shamat. (1993) The role of the gastrointestinal microflora in the metabolism of drugs. International Journal of Pharmaceutics 97:1-3, pages 1-13.
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Be-Sheng Kuo, James C. Poole, Kin-Kai Hwang & Haiyung Cheng. (1993) Pharmacokinetics and Metabolic Interconversion of Intravenous 4-Amino-5-chloro-2-[(methylsulfinyl)ethoxy]-N-[2-(diethylamino)ethyl]benzamide and Its Sulfide and Sulfone Metabolites in Rats. Journal of Pharmaceutical Sciences 82:7, pages 694-698.
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Haiyung Cheng & William J. Jusko. 1991. Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis. Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis 13 20 .
Kenneth F. Ilett, Lisa B.G. Tee, Philip T. Reeves & Rodney F. Minchin. (1990) Mebolism of drugs and other xenobiotics in the gut lumen and wall. Pharmacology & Therapeutics 46:1, pages 67-93.
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Be‐Sheng Kuo & Wolfgang A. Ritschel. (2006) Correlation between inhibitory effect on platelet aggregation and disposition of sulfinpyrazone and its metabolites in rabbits. Part II: Multiple dose study. Biopharmaceutics & Drug Disposition 8:1, pages 11-21.
Crossref
A.G. RENWICK, H.A. STRONG & C.F. GEORGE. 1986. Bioreduction in the Activation of Drugs. Bioreduction in the Activation of Drugs 64 .
A.G. Renwick, H.A. Strong & C.F. George. (1986) The role of the gut flora in the reduction of sulphoxide containing drugs. Biochemical Pharmacology 35:1, pages 64.
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