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Xenobiotica
the fate of foreign compounds in biological systems
Volume 14, 1984 - Issue 12
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Original Article

Selenium suppresses the metabolism of benzo[a]pyrene by rat-liver extracts, and exerts a dual effect on its mutagenicity

W. S. Lin Department of Biology, The University, Calgary, Alberta, T2N 1N4, Canada
,
C. Scrimshaw Department of Biology, The University, Calgary, Alberta, T2N 1N4, Canada
&
M. Kapoor Department of Biology, The University, Calgary, Alberta, T2N 1N4, Canada
Pages 893-902 | Received 19 Sep 1983, Published online: 30 Sep 2009

Citations (8)

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Guy Bompart, Philippe Puig, Bernard Pipy, Maryse Béraud & Marie‐Claude Souqual. (1989) In vitro influence of molybdenum on benzo[a]pyrene metabolism in hepatic and pulmonary rat microsomes. Journal of Toxicology and Environmental Health 26:4, pages 459-468.
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M. Kapoor & W. S. Lin. (1984) Studies on the induction of aryl hydrocarbon(benzo[a]pyrene) hydroxylase in Neurospora crassa, and its suppression by sodium selenite. Xenobiotica 14:12, pages 903-915.
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Articles from other publishers (6)

Manjeshwar Shrinath Baliga, Bantwal Raghavendra Vittaldas Baliga, Shaun Mathew Kandathil, Harshith P. Bhat & Praveen Kumar Vayalil. (2011) A review of the chemistry and pharmacology of the date fruits (Phoenix dactylifera L.). Food Research International 44:7, pages 1812-1822.
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Wael M. El-Sayed, Warda A. Hussin & Michael R. Franklin. (2007) The antimutagenicity of 2-substituted selenazolidine-4-(R)-carboxylic acids. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 627:2, pages 136-145.
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Guy Huel, Dave Campagna, Françoise Girard, Thierry Moreau & Philippe Blot. (2000) Does Selenium Reduce the Risk of Threatened Preterm Delivery Associated with Placental Cytochrome P450-1A1 Activity?. Environmental Research 84:3, pages 228-233.
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Byron Olson, James McDonaldJr.Jr., Tim Noblitt, Yiming Li & Ley Marisa. (1995) Modifying role of trace elements on the mutagenicity of benzo[a]pyrene. Mutation Research/Environmental Mutagenesis and Related Subjects 335:1, pages 21-26.
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Matti Laitinen, Risto Juvonen & Eino Hietanen. (1988) The effect of selenium on the hepatic drug metabolism and inducibility in rat. International Journal of Biochemistry 20:7, pages 675-681.
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P. Prasanna, M.M. Jacobs & S.K. Yang. (1987) Selenium inhibition of benzo[a]pyrene, 3-methylcholanthrene, and 3-methylcholanthrylene mutagenicity in Salmonella typhimurium strains TA98 and TA100. Mutation Research Letters 190:2, pages 101-105.
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