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Xenobiotica
the fate of foreign compounds in biological systems
Volume 14, 1984 - Issue 12
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Original Article

A species difference in the presystemic metabolism of carbazeran in dog and man

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Pages 935-945 | Received 20 Jan 1984, Published online: 30 Sep 2009

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Siva Nageswara Rao Gajula, Tanaaz Navin Nathani, Rashmi Madhukar Patil, Sasikala Talari & Rajesh Sonti. (2022) Aldehyde oxidase mediated drug metabolism: an underpredicted obstacle in drug discovery and development. Drug Metabolism Reviews 54:4, pages 427-448.
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Francesca Toselli, Melanie Golding, Johan Nicolaï, Eric Gillent & Hugues Chanteux. (2022) Drug clearance by aldehyde oxidase: can we avoid clinical failure?. Xenobiotica 52:8, pages 890-903.
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Christine Beedham. (2020) Aldehyde oxidase; new approaches to old problems. Xenobiotica 50:1, pages 34-50.
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Narges Cheshmazar, Siavoush Dastmalchi, Mineko Terao, Enrico Garattini & Maryam Hamzeh-Mivehroud. (2019) Aldehyde oxidase at the crossroad of metabolism and preclinical screening. Drug Metabolism Reviews 51:4, pages 428-452.
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Maki Miyamoto, Shinji Iwasaki, Ikumi Chisaki, Sayaka Nakagawa, Nobuyuki Amano & Hideki Hirabayashi. (2017) Comparison of predictability for human pharmacokinetics parameters among monkeys, rats, and chimeric mice with humanised liver. Xenobiotica 47:12, pages 1052-1063.
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Deepak Dalvie, Cathie Xiang, Ping Kang & Sue Zhou. (2013) Interspecies variation in the metabolism of zoniporide by aldehyde oxidase. Xenobiotica 43:5, pages 399-408.
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James Matthew Hutzler, Ronald Scott Obach, Deepak Dalvie & Michael A Zientek. (2013) Strategies for a comprehensive understanding of metabolism by aldehyde oxidase. Expert Opinion on Drug Metabolism & Toxicology 9:2, pages 153-168.
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Federica Vacondio, Claudia Silva, Marco Mor & Bernard Testa. (2010) Qualitative structure-metabolism relationships in the hydrolysis of carbamates. Drug Metabolism Reviews 42:4, pages 551-589.
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D. O’Connor, P. Jones, M. S. Chambers, R. Maxey, H. J. Szekeres, N. Szeto, P. Scott-Stevens, A. M. Macleod, M. Braun & B. Cato. (2006) Aldehyde oxidase and its contribution to the metabolism of a structurally novel, functionally selective GABAA α5-subtype inverse agonist. Xenobiotica 36:4, pages 315-330.
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D. J. P. Critchley, D. J. Rance & C. Beedham. (1994) Biotransformation of carbazeran in guinea pig: Effect of hydralazine pretreatment. Xenobiotica 24:1, pages 37-47.
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Peter Dogterom, Gerhard Zbinden & Gerd K. Reznik. (1992) Cardiotoxicity of Vasodilators and Positive Inotropic/Vasodilating Drugs in Dogs: An Overview. Critical Reviews in Toxicology 22:3-4, pages 203-241.
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