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Xenobiotica
the fate of foreign compounds in biological systems
Volume 15, 1985 - Issue 6
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Original Article

The metabolism of 14C-cyclohexylamine in mice and two strains of rat

A. Roberts Clinical Pharmacology Group, Faculty of Medicine, University of Southampton, Medical&Biological Sciences Building, Bassett Crescent East, Southampton, SO9 3TU, UK
&
A. G. Renwick Clinical Pharmacology Group, Faculty of Medicine, University of Southampton, Medical&Biological Sciences Building, Bassett Crescent East, Southampton, SO9 3TU, UK
Pages 477-483 | Received 17 Sep 1984, Published online: 30 Sep 2009

Citations (16)

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Read on this site (2)

Farid E. Ahmed & David B. Thomas. (1992) Assessment of the Carcinogenicity of the Nonnutritive Sweetener Cyclamate. Critical Reviews in Toxicology 22:2, pages 81-118.
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A. G. Renwick. (1986) The metabolism of intense sweeteners. Xenobiotica 16:10-11, pages 1057-1071.
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Articles from other publishers (14)

Michelle L. Kearns, Fionn MacAindriu & Clare M. Reynolds. (2022) The Impact of Non-caloric Sweeteners on Male Fertility: A Systematic Review and Narrative Synthesis in Rodent Models. Frontiers in Nutrition 9.
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José Germano Ferraz de Arruda, Alex Tadeu Martins & Reinaldo Azoubel. (2003) Ciclamato de sódio e rim fetal. Revista Brasileira de Saúde Materno Infantil 3:2, pages 147-150.
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Ronald A. Hill, Sonali Rudra, Bo Peng, David S. Roane, Jeffrey K. Bounds, Yang Zhang, Ahmad Adloo & Tiansheng Lu. (2003) Hydroxyl-Substituted sulfonylureas as potent inhibitors of specific [3H]Glyburide binding to rat brain synaptosomes. Bioorganic & Medicinal Chemistry 11:9, pages 2099-2113.
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K Walton, R Walker, J.J.M van de Sandt, J.V Castell, A.G.A.A Knapp, G Kozianowski, M Roberfroid & B Schilter. (1999) The application of in vitro data in the derivation of the Acceptable Daily Intake of food additives. Food and Chemical Toxicology 37:12, pages 1175-1197.
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G.D. Heaton & A.G. Renwick. (1991) The effects of high dietary concentrations of sodium saccharin on in vivo metabolism of xenobiotics in rats. Food and Chemical Toxicology 29:5, pages 305-312.
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Dianne M. Creasy, Graham R. Ford & Tim J.B. Gray. (1990) The morphogenesis of cyclohexylamine-induced testicular atrophy in the rat: In vivo and in vitro studies. Experimental and Molecular Pathology 52:2, pages 155-169.
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MARILYN C. HENDERSON. 1990. Nitrogen and Phosphorus Solvents. Nitrogen and Phosphorus Solvents 24 37 .
Ilse-Dore Adler & John Ashby. (1989) The present lack of evidence for unique rodent germ-cell mutagens. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 212:1, pages 55-66.
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A. Roberts & A.G. Renwick. (1989) The pharmacokinetics and tissue concentrations of cyclohexylamine in rats and mice. Toxicology and Applied Pharmacology 98:2, pages 230-242.
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A. Roberts, A.G. Renwick, G. Ford, D.M. Creasy & I. Gaunt. (1989) The metabolism and testicular toxicity of cyclohexylamine in rats and mice during chronic dietary administration. Toxicology and Applied Pharmacology 98:2, pages 216-229.
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MARVIN S. LEGATOR & BARBARA L. HARPER. (1988) Mutagenicity Screening/in Vitro Testing?the End of an Era; Animal and Human Studies?the Direction for the Future. Annals of the New York Academy of Sciences 534:1 Living in a C, pages 833-844.
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A. Roberts, A.G. Renwick, D.M. Creasy, G.P. Ford & I.F. Gaunt. (2016) The DA Rat as an Aid to Toxicological Evaluation. Human Toxicology 7:2, pages 228-228.
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A.G. RENWICK. 1988. Role of the Gut Flora in Toxicity and Cancer. Role of the Gut Flora in Toxicity and Cancer 175 206 .
A.G. Renwick. (1985) The fate of intense sweeteners in the body. Food Chemistry 16:3-4, pages 281-301.
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