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Xenobiotica
the fate of foreign compounds in biological systems
Volume 15, 1985 - Issue 10
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Original Article

Hepatic uptake and metabolism of pentacaine: A study with microsomes, hepatocytes and perfused livers of rats

M. Štefek Institute of Experimental Pharmacology, Centre of Physiological Sciences, Slovak Academy of Sciences, Dúbravská cesta, 842 16, Bratislava, Czechoslovakia
&
Š. Bezek Institute of Experimental Pharmacology, Centre of Physiological Sciences, Slovak Academy of Sciences, Dúbravská cesta, 842 16, Bratislava, Czechoslovakia
Pages 805-812 | Received 06 Oct 1984, Published online: 30 Sep 2009

Citations (8)

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Read on this site (2)

Federica Vacondio, Claudia Silva, Marco Mor & Bernard Testa. (2010) Qualitative structure-metabolism relationships in the hydrolysis of carbamates. Drug Metabolism Reviews 42:4, pages 551-589.
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SK. Bezek, M. Kukan, W. F. Pool & T. F. Woolf. (1996) The effect of cytochromes P4501A induction and inhibition on the disposition of the cognition activator tacrine in rat hepatic preparations. Xenobiotica 26:9, pages 935-946.
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Articles from other publishers (6)

Z Kállay, M Ďurišová, T Trnovec & V Svoboda. (1990) Effect of gamma-irradiation on disposition of the local anaesthetic, carbisocaine in rabbits. Journal of Pharmacy and Pharmacology 42:12, pages 871-873.
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Vladimir Vegh, Jozef Cizmarik & Klaus Hahnenkamp. (2006) Is there a place for local anesthetics structurally different from classical amid or ester local anesthetics?. Current Opinion in Anaesthesiology 19:5, pages 509-515.
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Š. Bezek, V. Ščasnár, M. Kukan & T. Trnovec. (2006) Kinetics of biliary elimination of pentacaine in rats. Biopharmaceutics & Drug Disposition 11:5, pages 403-409.
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M. Kukan, Š. Bezek, V. Ščasnár, M. Ďurišová & T. Trnovec. (2006) Effects of inducers and inhibitors of mixed‐function oxidases on the biliary excretion of pentacaine metabolites. Biopharmaceutics & Drug Disposition 11:5, pages 395-401.
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Anna C. Macintyre & David J. Cutler. (1988) The potential role of lysosomes in tissue distribution of weak bases. Biopharmaceutics & Drug Disposition 9:6, pages 513-526.
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M. Štefek, L. Beneš & V. Kováčik. (1986) Identification ofin vitro rat metabolites of pentacaine, a carbanilate local anaesthetic, by gas chromatography/mass spectrometry. Biological Mass Spectrometry 13:4, pages 193-198.
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