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Xenobiotica
the fate of foreign compounds in biological systems
Volume 15, 1985 - Issue 11
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Original Article

Isolation and characterization of the four antipyrine glucuronides and determination of their urinary excretion pattern in man by a reversed-phase h.p.l.c. assay

H. Bässmann Institut für Pharmakologie und Toxikologie, Technische Universität Braunschweig, FR, Germany
,
J. Böttcher Institut für Pharmakologie und Toxikologie, Technische Universität Braunschweig, FR, Germany
,
R. Schüppel Institut für Pharmakologie und Toxikologie, Technische Universität Braunschweig, FR, Germany
&
V. Wray Gesellschaft für Biotechnologische Forschung, Braunschweig-Stöckheim, FR, Germany
Pages 941-952 | Received 15 Nov 1984, Published online: 30 Sep 2009

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Kazutoshi Watanabe, Masao Taniguchi & Masaki Shinoda. (2003) Synthesis of the metabolites of a free radical scavenger edaravone (MCI-186, Radicut™). Redox Report 8:3, pages 157-161.
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C. Palette, F. Dubor, V. Rovei & C. Advenier. (1993) Determination of antipyrine sulphoconjugates in isolated cultured rat hepatocytes. Xenobiotica 23:2, pages 181-191.
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Articles from other publishers (9)

Hiroyuki Nakajima, Takeshi Nakanishi, Kiyohiko Nakai, Shigeki Matsumoto, Keiichi Ida, Takuo Ogihara & Nobuo Ohzawa. (2002) Studies on the Metabolic Fate of M17055 a Novel Diuretic (4): Species Difference in Metabolic Pathway and Identification of Human CYP Isoform Responsible for the Metabolism of M17055. Drug Metabolism and Pharmacokinetics 17:1, pages 60-74.
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B. Lu, M. Koimur & D. Westerlund. (1997) Separation of phenolic compounds and corresponding glucuronides by coupled-column micellar reversed-phase liquid chromatography. Chromatographia 46:1-2, pages 72-78.
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I. Velic, M. Metzler, H.G. Hege & J. Weymann. (1995) Separation and identification of phase I and phase II [14C]antipyrine metabolites in rat and dog urine. Journal of Chromatography B: Biomedical Sciences and Applications 666:1, pages 139-147.
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C. Palette, P. Cordonnier, F. Tillequin, M. Koch, C. Advenier & M. Pays. (1994) Isolation and purification of three glucuronides of antipyrine. Proposal for an original analytical method for quantitation of sulpho- and glucuroconjugated metabolites. Biomedical Chromatography 8:2, pages 77-84.
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C. Palette, P. Cordonnier, E. Naline, C. Advenier & M. Pays. (1991) High-performance liquid chromatographic method for the determination of the three main oxidative and 3-carboxylic antipyrine metabolites in human urine. Journal of Chromatography B: Biomedical Sciences and Applications 563:1, pages 103-113.
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T. F. Woolf & T. Chang. (1989) Preparation of diastereomeric β-d-glucuronides of the bronchodilator procaterol using immobilized rabbit liver microsomal enzymes. European Journal of Drug Metabolism and Pharmacokinetics 14:2, pages 111-116.
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Daniel S. Sitar. (1989) Human drug metabolism in vivo. Pharmacology & Therapeutics 43:3, pages 363-375.
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K. Krohn & C. Stenns. (2006) Chemical Synthesis of Phase‐I‐ and Phase‐II‐Metabolites of Antipyrine. Archiv der Pharmazie 322:6, pages 351-354.
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H.-M. Schiebel, O. Gries, R. Schüppel & P. Schulze. (1987) Identification of conjugated metabolites of pyrazolone drugs in human urine by pyrolysis-mass spectrometry. Journal of Analytical and Applied Pyrolysis 10:4, pages 267-281.
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