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Xenobiotica
the fate of foreign compounds in biological systems
Volume 15, 1985 - Issue 1
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Research Article

Isolation and identification of hydroxylated maprotiline metabolites

U. Breyer-Pfaff Institut für Toxikologie, Universität Tübingen, D-7400, Tübingen, FR, Germany
,
M. Kroeker Institut für Toxikologie, Universität Tübingen, D-7400, Tübingen, FR, Germany
,
T. Winkler Ciba-Geigy, AG, CH-4002, Basel, Switzerland
&
P. Kriemler Ciba-Geigy, AG, CH-4002, Basel, Switzerland
Pages 57-66 | Received 03 Jan 1984, Published online: 22 Sep 2008

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Shu-Feng Zhou, Jun-Ping Liu & Balram Chowbay. (2009) Polymorphism of human cytochrome P450 enzymes and its clinical impact. Drug Metabolism Reviews 41:2, pages 89-295.
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Josip Radić, Dorotea Perović, Ema Gričar & Mitja Kolar. (2022) Potentiometric Determination of Maprotiline Hydrochloride in Pharmaceutical and Biological Matrices Using a Novel Modified Carbon Paste Electrode. Sensors 22:23, pages 9201.
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Nuno P.F. Gonçalves, Zsuzsanna Varga, Stéphane Bouchonnet, Valeria Dulio, Nikiforos Alygizakis, Federica Dal Bello, Claudio Medana & Paola Calza. (2021) Study of the photoinduced transformations of maprotiline in river water using liquid chromatography high-resolution mass spectrometry. Science of The Total Environment 755, pages 143556.
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Shu-Feng Zhou. (2009) Polymorphism of Human Cytochrome P450 2D6 and Its Clinical Significance. Clinical Pharmacokinetics 48:12, pages 761-804.
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Sharon J. Gardiner & Evan J. Begg. (2006) Pharmacogenetics, Drug-Metabolizing Enzymes, and Clinical Practice. Pharmacological Reviews 58:3, pages 521-590.
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Norbert Thuerauf & Jens Lunkenheimer. (2006) The impact of the CYP2D6-polymorphism on dose recommendations for current antidepressants. European Archives of Psychiatry and Clinical Neuroscience 256:5, pages 287-293.
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Lars Brachtendorf, Alexander Jetter, K. Tobias Beckurts, Arnulf H. Hölscher & Uwe Fuhr. (2002) Cytochrome P-450 Enzymes Contributing to Demethylation of Maprotiline in Man. Pharmacology & Toxicology 90:3, pages 144-149.
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J. Kirchheiner, K. Brøsen, M. L. Dahl, L. F. Gram, S. Kasper, I. Roots, F. Sjöqvist, E. Spina & J. Brockmöller. (2001) CYP2D6 and CYP2C19 genotype‐based dose recommendations for antidepressants:
a first step towards subpopulation‐specific dosages. Acta Psychiatrica Scandinavica 104:3, pages 173-192.
Crossref
L Firkusny & CH Gleiter. (2012) Maprotiline metabolism appears to co‐segregate with the genetically‐ determined CYP2D6 polymorphic hydroxylation of debrisoquine.. British Journal of Clinical Pharmacology 37:4, pages 383-388.
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G. Laux, A. Delini-Stula, U. Breyer-Pfaff, J. Demling, D. Ebert, W. Pöldinger, S. Kasper, M. Osterheider, O. Dietmaier, H.-J. Möller & J. Fuger. 1993. Neuro-Psychopharmaka. Neuro-Psychopharmaka 105 268 .
J. Elks & C. R. Ganellin. 1990. Dictionary of Drugs. Dictionary of Drugs 748 844 .

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