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Xenobiotica
the fate of foreign compounds in biological systems
Volume 15, 1985 - Issue 1
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Research Article

The metabolism of gliclazide in man

T. Oida Research Laboratories, Dainippon Pharmaceutical Co. Ltd, Osaka, Japan
,
K. Yoshida Research Laboratories, Dainippon Pharmaceutical Co. Ltd, Osaka, Japan
,
A. Kagemoto Research Laboratories, Dainippon Pharmaceutical Co. Ltd, Osaka, Japan
,
Y. Sekine Research Laboratories, Dainippon Pharmaceutical Co. Ltd, Osaka, Japan
&
T. Higashijima Department of Biophysics and Biochemistry, University of Tokyo, Tokyo, Japan
Pages 87-96 | Received 20 Jun 1984, Published online: 22 Sep 2008

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Elaine Chow, Emily WM Poon, Benny SP Fok, Juliana CN Chan & Brian Tomlinson. (2019) CYP2C19*2 Polymorphism Is Associated with Impaired Oral Clearance of Gliclazide in Healthy Chinese. Pharmacogenomics and Personalized Medicine 12, pages 397-401.
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Kilari Eswar Kumar & Shaik Mastan. (2011) Effect of protease inhibitors (indinavir and ritonavir) on the pharmacokinetics of gliclazide in rabbits. Research and Reports in Endocrine Disorders 1, pages 1-9.
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A. Barracca, O. Ledda, B. Michittu, G. F. Pili, O. Manca, A. Pani & P. Alfieri. (1998) Acute renal failure after massive ingestion of gliclazide in a suicide attempt. Renal Failure 20:3, pages 533-537.
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A. Rieutord, I. Stupans, G. M. Shenfield & A. S. Gross. (1995) Gliclazide hydroxylation by rat liver microsomes. Xenobiotica 25:12, pages 1345-1354.
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Articles from other publishers (23)

Xue-Ting Shao, Yue-Tong Zhao, Bing Jiang, Yan-Ying Li, Jian-Guo Lin & De-Gao Wang. (2023) Evaluation of Three Chronic Diseases by Selected Biomarkers in Wastewater. ACS ES&T Water 3:4, pages 943-953.
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Amrinder Singh, Kaicun Zhao, Celia Bell & Ajit J. Shah. (2020) Effect of berberine on in vitro metabolism of sulfonylureas: A herb–drug interactions study . Rapid Communications in Mass Spectrometry.
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Maja Ðanić, Bojan Stanimirov, Nebojša Pavlović, Saša Vukmirović, Jelena Lazić, Hani Al-Salami & Momir Mikov. (2019) Transport and Biotransformation of Gliclazide and the Effect of Deoxycholic Acid in a Probiotic Bacteria Model. Frontiers in Pharmacology 10.
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Swagatika Sahoo, Hulda S. Haraldsdóttir, Ronan M. T. Fleming & Ines Thiele. (2015) Modeling the effects of commonly used drugs on human metabolism. FEBS Journal 282:2, pages 297-317.
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Carolina Cieniak, Rui Liu, Alexandra Fottinger, Sheila A.M. Smiley, Jose A. Guerrero-Analco, Steffany A.L. Bennett, Pierre S. Haddad, Alain Cuerrier, Ammar Saleem, John T. Arnason & Brian C. Foster. (2013) In vitro inhibition of metabolism but not transport of gliclazide and repaglinide by Cree medicinal plant extracts. Journal of Ethnopharmacology 150:3, pages 1087-1095.
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Hussaina Banu, N. Renuka & Geetha Vasanthakumar. (2011) Reduced catalytic activity of human CYP2C9 natural alleles for gliclazide: Molecular dynamics simulation and docking studies. Biochimie 93:6, pages 1028-1036.
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S.K. Mastan & K. Eswar Kumar. (2010) Influence of atazanavir on the pharmacodynamics and pharmacokinetics of gliclazide in animal models. International Journal of Diabetes Mellitus 2:1, pages 56-60.
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Yuan Yao, Wei-Wei Han, Yi-Han Zhou, Ze-Sheng Li, Qiang Li, Xiao-Yan Chen & Da-Fang Zhong. (2009) The metabolism of CYP2C9 and CYP2C19 for gliclazide by homology modeling and docking study. European Journal of Medicinal Chemistry 44:2, pages 854-861.
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H Xu, K M Williams, W S Liauw, M Murray, R O Day & A J McLachlan. (2008) Effects of St John's wort and CYP2C9 genotype on the pharmacokinetics and pharmacodynamics of gliclazide . British Journal of Pharmacology 153:7, pages 1579-1586.
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ML Becker, LE Visser, PH Trienekens, A Hofman, RHN van Schaik & BHCh Stricker. (2007) Cytochrome P450 2C9 *2 and *3 Polymorphisms and the Dose and Effect of Sulfonylurea in Type II Diabetes Mellitus. Clinical Pharmacology & Therapeutics 83:2, pages 288-292.
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David J. Elliot, Suharjono, Benjamin C. Lewis, Elizabeth M. J. Gillam, Donald J. Birkett, Annette S. Gross & John O. Miners. (2007) Identification of the human cytochromes P450 catalysing the rate‐limiting pathways of gliclazide elimination. British Journal of Clinical Pharmacology 64:4, pages 450-457.
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Mahmoud Loubani, Alan Fowler, Nicholas B. Standen & Manuel Galiñanes. (2005) The effect of gliclazide and glibenclamide on preconditioning of the human myocardium. European Journal of Pharmacology 515:1-3, pages 142-149.
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Mario Thevis, Hans Geyer & Wilhelm Schänzer. (2005) Identification of oral antidiabetics and their metabolites in human urine by liquid chromatography/tandem mass spectrometry-a matter for doping control analysis. Rapid Communications in Mass Spectrometry 19:7, pages 928-936.
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Naji Najib, Nasir Idkaidek, M. Beshtawi, Mohammed Bader, Isra' Admour, S. Mahmood Alam, Q. Zaman & Ruwayda Dham. (2002) Bioequivalence evaluation of two brands of gliclazide 80 mg tablets (Glyzide ® & Diamicron ® ) — in healthy human volunteers . Biopharmaceutics & Drug Disposition 23:5, pages 197-202.
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Khalid A.J. Al Khaja PhD, Reginald P. Sequeira PhD, Vijay S. Mathur MD D.Phil FAMS, Awatif H.H. Damanhori MBBCh.Abdul Wahab M. Abdul Wahab FRCS. (2002) Family physicians’ and general practitioners’ approaches to drug management of diabetic hypertension in primary care. Journal of Evaluation in Clinical Practice 8:1, pages 19-30.
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Gaetano Crepaldi & Paola Fioretto. (2000) Gliclazide modified release: Its place in the therapeutic Armamentarium. Metabolism 49:10, pages 21-25.
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Andrew Harrower. (2000) Gliclazide modified release: From once-daily administration to 24-hour blood glucose control. Metabolism 49:10, pages 7-11.
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L. Groop & G. Neugebauer. 1996. Oral Antidiabetics. Oral Antidiabetics 199 259 .
S. L. Ali, H. H. Blume & B. S. Schug. 1996. Oral Antidiabetics. Oral Antidiabetics 73 128 .
D.B. Campbell, R. Lavielle & C. Nathan. (1991) The mode of action and clinical pharmacology of gliclazide: a review. Diabetes Research and Clinical Practice 14, pages S21-S36.
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J. Elks & C. R. Ganellin. 1990. Dictionary of Drugs. Dictionary of Drugs 590 616 .
Von Heiner Glombik & Rudi Weyer. 1986. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques 281 343 .
Xueting Shao, Yue-Tong Zhao, Bing Jiang, Yanying Li, Jianguo Lin & Degao Wang. (2022) Estimating Hypertension, Diabetes, and Gout Prevalence to Evaluate Public Health by Wastewater-Based Epidemiology. SSRN Electronic Journal.
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