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Xenobiotica
the fate of foreign compounds in biological systems
Volume 15, 1985 - Issue 4
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Research Article

Metabolic studies of a podophyllotoxin derivative (VP16) in the isolated perfused liver

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Pages 343-350 | Received 09 Jul 1984, Published online: 22 Sep 2008

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Gerald A. Le Blanc & David J. Waxman. (1989) Interaction of Anticancer Drugs with Hepatic Monooxygenase Enzymes. Drug Metabolism Reviews 20:2-4, pages 395-439.
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Zhiming Wen, Melanie N. Tallman, Shazia Y. Ali & Philip C. Smith. (2007) UDP-Glucuronosyltransferase 1A1 Is the Principal Enzyme Responsible for Etoposide Glucuronidation in Human Liver and Intestinal Microsomes: Structural Characterization of Phenolic and Alcoholic Glucuronides of Etoposide and Estimation of Enzyme Kinetics. Drug Metabolism and Disposition 35:3, pages 371-380.
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Giuseppe Toffoli, Giuseppe Corona, Barbara Basso & Mauro Boiocchi. (2004) Pharmacokinetic Optimisation of Treatment with Oral Etoposide. Clinical Pharmacokinetics 43:7, pages 441-466.
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Yuichiro Watanabe, Miki Nakajima, Noriko Ohashi, Toshiyuki Kume & Tsuyoshi Yokoi. (2003) Glucuronidation of Etoposide in Human Liver Microsomes Is Specifically Catalyzed by UDP-Glucuronosyltransferase 1A1. Drug Metabolism and Disposition 31:5, pages 589-595.
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Clinton F. Stewart. (1994) Use of etoposide in patients with organ dysfunction: pharmacokinetic and pharmacodynamic considerations. Cancer Chemotherapy and Pharmacology 34:S1, pages S76-S83.
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U. Schuler & G. Ehninger. 1994. Acute Leukemias IV. Acute Leukemias IV 145 153 .
Maria Grazia Donelli, Massimo Zucchetti, Donatella Gentili & Maurizio D’Incalci. 1993. Drugs and the Liver: High Risk Patients and Transplantation. Drugs and the Liver: High Risk Patients and Transplantation 105 111 .
Irene B. Larripa, Marta A. Carballo, Marta M. Mudry & Mabel L. Labal de Vinuesa. (2012) Etoposide and Teniposide: In Vivo and In Vitro Genotoxic Studies. Drug Investigation 4:5, pages 365-375.
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J. J. M. Holthuis. (1988) Etoposide and teniposide. Pharmaceutisch Weekblad Scientific Edition 10:3, pages 101-116.
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Joost J.M Holthuis, Pieter E Postmus, Willem J Van Oort, Bram Hulshoff, Harriët Verleun, Dirk Th Sleijfer & Nanno H Mulder. (1986) Pharmacokinetics of high dose etoposide (VP 16–213). European Journal of Cancer and Clinical Oncology 22:10, pages 1149-1155.
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Massimo Broggini, Cosmo Rossi, Emilio Benfenati, Maurizio D'Incalci, Roberto Fanelli & Pierluigi Gariboldi. (1985) Horseradish peroxidase/hydrogen peroxide-catalyzed oxidation of VP16-213. Identification of a new metabolite. Chemico-Biological Interactions 55, pages 215-224.
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