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Xenobiotica
the fate of foreign compounds in biological systems
Volume 15, 1985 - Issue 7
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Research Article

Isoprene metabolism by liver microsomal mono-oxygenases

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Pages 591-597 | Received 15 Jun 1984, Published online: 22 Sep 2008

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E. TAREKE, B. T. GOLDING, R. D. SMALL & M. TORNQVIST. (1998) Haemoglobin adducts from isoprene and isoprene monoepoxides. Xenobiotica 28:7, pages 663-672.
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R. D. SMALL, B. T. GOLDING & W. P. WATSON. (1997) Species differences in the stereochemistry of the metabolism of isoprene in vitro. Xenobiotica 27:11, pages 1155-1164.
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Articles from other publishers (34)

Chloe Biren, Luyu Zhang, Deepak Bhandari, Benjamin C. Blount & Víctor R. De Jesús. (2020) Isoprene Exposure in the United States Based on Urinary IPM3: NHANES 2015–2016. Environmental Science & Technology 54:4, pages 2370-2378.
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Hae-Miru Lee, Cho-Won Kim, Kyung-A Hwang, Dal-Woong Choi & Kyung-Chul Choi. (2016) Three components of cigarette smoke altered the growth and apoptosis of metastatic colon cancer cells via inducing the synthesis of reactive oxygen species and endoplasmic reticulum stress. Environmental Toxicology and Pharmacology 45, pages 80-89.
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Yan Li, Avishay Pelah, Jing An, Ying-Xin Yu & Xin-Yu Zhang. (2014) Concentration- and time-dependent genotoxicity profiles of isoprene monoepoxides and diepoxide, and the cross-linking potential of isoprene diepoxide in cells. Toxicology Reports 1, pages 36-45.
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Paweł Mochalski, Andreas Sponring, Julian King, Karl Unterkofler, Jakob Troppmair & Anton Amann. (2013) Release and uptake of volatile organic compounds by human hepatocellular carcinoma cells (HepG2) in vitro. Cancer Cell International 13:1, pages 72.
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. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 52 .
Petra Begemann, Gunnar Boysen, Nadia I. Georgieva, Ramiah Sangaiah, Karl M. Koshlap, Hasan Koc, Daping ZhangBernard T. GoldingAvram Gold & James A. Swenberg. (2011) Identification and Characterization of 2′-Deoxyadenosine Adducts Formed by Isoprene Monoepoxides in Vitro . Chemical Research in Toxicology 24:7, pages 1048-1061.
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. (2011) Scientific Opinion on Flavouring Group Evaluation 25, Revision 2 (FGE.25Rev2): Aliphatic and aromatic hydrocarbons from chemical group 31. EFSA Journal 9:6, pages 2177.
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Julian King, Helin Koc, Karl Unterkofler, PaweŁ Mochalski, Alexander Kupferthaler, Gerald Teschl, Susanne Teschl, Hartmann Hinterhuber & Anton Amann. (2010) Physiological modeling of isoprene dynamics in exhaled breath. Journal of Theoretical Biology 267:4, pages 626-637.
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. (2010) Scientific Opinion on Flavouring Group Evaluation 25Rev1: Aliphatic and aromatic hydrocarbons from chemical group 31. EFSA Journal 8:5, pages 1334.
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. (2008) Flavouring Group Evaluation 25, (FGE.25) - Aliphatic and aromatic hydrocarbons from chemical group 31 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food. EFSA Journal 6:12, pages 918.
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Harrell E. Hurst. 2007. Reviews of Environmental Contamination and Toxicology. Reviews of Environmental Contamination and Toxicology 131 179 .
Charlotta Fred, Jan Grawé & Margareta Törnqvist. (2005) Hemoglobin adducts and micronuclei in rodents after treatment with isoprene monoxide or butadiene monoxide. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 585:1-2, pages 21-32.
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Jan J.P Bogaards, Andreas P Freidig & Peter J van Bladeren. (2001) Prediction of isoprene diepoxide levels in vivo in mouse, rat and man using enzyme kinetic data in vitro and physiologically-based pharmacokinetic modelling. Chemico-Biological Interactions 138:3, pages 247-265.
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György András Csanády & Johannes Georg Filser. (2001) Toxicokinetics of inhaled and endogenous isoprene in mice, rats, and humans. Chemico-Biological Interactions 135-136, pages 679-685.
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William P Watson, Lisa Cottrell, Daping Zhang & Bernard T Golding. (2001) Metabolism and molecular toxicology of isoprene. Chemico-Biological Interactions 135-136, pages 223-238.
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P. J. van Bladeren, J. J. P. Bogaards, N. H. P. Cnubben & E. M. Hissink. 2001. Biological Reactive Intermediates VI. Biological Reactive Intermediates VI 551 558 .
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Jan J.P. Bogaards, Joke C. Venekamp & Peter J. van Bladeren. (1996) The biotransformation of isoprene and the two isoprene monoepoxides by human cytochrome P450 enzymes, compared to mouse and rat liver microsomes. Chemico-Biological Interactions 102:3, pages 169-182.
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J.G. Filser, Gy.A. Csanády, B. Denk, M. Hartmann, A. Kaufmann, W. Kessler, P.E. Kreuzer, C. Pütz, J.H. Shen & P. Stei. (1996) Toxicokinetics of isoprene in rodents and humans. Toxicology 113:1-3, pages 278-287.
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Moreno Paolini, Renata Mesirca, Laura Pozzetti, Andrea Sapone & Giorgio Cantelli-Forti. (1995) Induction of CYP2B1 mediated pentoxyresorufin O-dealkylase activity in different species, sex and tissue by prototype 2B1-inducers. Chemico-Biological Interactions 95:1-2, pages 127-139.
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Miranda Cornet, Walter Sonck, André Callaerts, Georg Csanády, Antoine Vercruysse, Reinhold J. Laib & Vera Rogiers. (1991) In vitro biotransformation of 2-methylpropene (isobutene): Epoxide formation in mice liver. Archives of Toxicology 65:4, pages 263-267.
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P. E. Kreuzer, W. Kessler, H. F. Welter, C. Baur & J. G. Filser. (1991) Enzyme specific kinetics of 1,2-epoxybutene-3 in microsomes and cytosol from livers of mouse, rat, and man. Archives of Toxicology 65:1, pages 59-67.
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. 1991. Toxicological Evaluations. Toxicological Evaluations 13 37 .
M G Bird. (1990) Future directions--toxicology studies of 1,3-butadiene and isoprene.. Environmental Health Perspectives 86, pages 99-102.
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R L MelnickJ H RoycroftB J ChouH A RaganR A Miller. (1990) Inhalation toxicology of isoprene in F344 rats and B6C3F1 mice following two-week exposures.. Environmental Health Perspectives 86, pages 93-98.
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P G GervasiV Longo. (1990) Metabolism and mutagenicity of isoprene.. Environmental Health Perspectives 86, pages 85-87.
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Moreno Paolini, Carlo Bauer, Glan Luigi Blagi & Giorgio Cantelli-Forti. (1989) Do cytochromes P-448 and P-450 have different functions?. Biochemical Pharmacology 38:14, pages 2223-2225.
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C.G. Ginkel, E. Jong, J.W.R. Tilanus & J.A.M. Bont. (1987) Microbial oxidation of isoprene, a biogenic foliage volatile and of 1,3-butadiene, an anthropogenic gas. FEMS Microbiology Letters 45:5, pages 275-279.
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A.R. Dahl, L.S. Birnbaum, J.A. Bond, P.G. Gervasi & R.F. Henderson. (1987) The fate of isoprene inhaled by rats: Comparison to butadiene. Toxicology and Applied Pharmacology 89:2, pages 237-248.
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Ian N.H. White, Melanie L. Green, Eric Bailey & Peter B. Farmer. (1986) Metabolic activation of olefins. Biochemical Pharmacology 35:9, pages 1569-1575.
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V. Longo, L. Citti & P.G. Gervasi. (1985) Hepatic microsomal metabolism of isoprene in various rodents. Toxicology Letters 29:1, pages 33-37.
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