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Xenobiotica
the fate of foreign compounds in biological systems
Volume 15, 1985 - Issue 7
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Research Article

Bucolome N-glucuronide: Purification and identification of a major metabolite of bucolome in rat bile

K. Mohri Department of Biopharmacy, Meiji College of Pharmacy, 1-35-23, Nozawa Setagaya-ku, Tokyo, 154, Japan
,
T. Uesugi Department of Biopharmacy, Meiji College of Pharmacy, 1-35-23, Nozawa Setagaya-ku, Tokyo, 154, Japan
&
K. Kamisaka The 3rd Department of Internal Medicine, Tokyo Medical and Dental University, 1-5-45, Yushima Bunkyo-ku, Tokyo, 113, Japan
Pages 615-621 | Received 25 Jul 1984, Published online: 22 Sep 2008

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W. R. Rush, O. F. Alexander, D. J. Hall, R. J. Dow, L. Tokes, L. Kurz & D. J. M. Graham. (1990) The metabolism of nafimidone hydrochloride in the dog, primates and man. Xenobiotica 20:1, pages 123-132.
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Articles from other publishers (12)

Chester L BowenJonathan Volpatti, Jessica Cades, Hermes Licea-Perez & Christopher A Evans. (2012) Evaluation of glucuronide metabolite stability in dried blood spots. Bioanalysis 4:23, pages 2823-2832.
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Minoru Uchiyama, Haruo Iwabuchi, Fujiko Tsuruta, Koji Abe, Makoto Takahashi, Hiroko Koda, Minoru Oguchi, Osamu Okazaki & Takashi Izumi. (2011) Pharmacokinetics, Metabolism, and Disposition of Rivoglitazone, a Novel Peroxisome Proliferator-Activated Receptor γ Agonist, in Rats and Monkeys. Drug Metabolism and Disposition 39:4, pages 653-666.
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Humihisa Kanoh, Makiko Tada, Yoshihiro Uesawa & Kiminori Mohri. (2011) Bucolome N-Glucuronide Formation: Species Differences and Identification of Human UDP-Glucuronosyltransferase Isoforms. Pharmacology & Pharmacy 02:04, pages 361-369.
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Humihisa Kanoh, Makiko Tada, Shinichi Ikushiro & Kiminori Mohri. (2011) Characterization of Bucolome N-Glucuronide Formation: Tissue Specificity and Identification of Rat UDP-Glucuronosyltransferase Isoform (s). Pharmacology & Pharmacy 02:03, pages 151-158.
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Minoru Uchiyama, Thomas Fischer, Juergen Mueller, Minoru Oguchi, Naotoshi Yamamura, Hiroko Koda, Haruo Iwabuchi & Takashi Izumi. (2010) Identification of Novel Metabolic Pathways of Pioglitazone in Hepatocytes: N -Glucuronidation of Thiazolidinedione Ring and Sequential Ring-Opening Pathway . Drug Metabolism and Disposition 38:6, pages 946-956.
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Cecilia H. Marzabadi, Richard W. Franck & Raymond F. Schinazi. (2002) The Synthesis and Biological Evaluation of Novel Bridging Nucleoside Analogues. Bioorganic & Medicinal Chemistry 10:2, pages 273-281.
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Kiminori Mohri, Yoshihiro Uesawa & Takashi Uesugi. (2001) Metabolism of bucolome in rats. Journal of Chromatography B: Biomedical Sciences and Applications 759:1, pages 153-159.
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Abdul E. Mutlib, Ronald J. Gerson, Paul C. Meunier, Patrick J. Haley, Hao Chen, Lawrence S. Gan, Marc H. Davies, Brian Gemzik, David D. Christ, David F. Krahn, Jay A. Markwalder, Steven P. Seitz, Richard T. Robertson & Gerald T. Miwa. (2000) The Species-Dependent Metabolism of Efavirenz Produces a Nephrotoxic Glutathione Conjugate in Rats. Toxicology and Applied Pharmacology 169:1, pages 102-113.
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Ming‐Shang Kuo, David A. Yurek, Steve A. Mizsak, Mark D. Prairie, Sally J. Mattern & Thomas F. Dekoning. (1999) Isolation and identification of a major metabolite of PNU‐107859, an MMP inhibitor from the biliary fluid of rats. Journal of Pharmaceutical Sciences 88:7, pages 705-708.
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Suzanne M. Neighbors, William H. Soine & Sheela G. Paibir. (1995) Synthesis of N-β-d-glucopyranosyluronate derivatives of barbital, phenobarbital, metharbital, and mephobarbital. Carbohydrate Research 269:2, pages 259-272.
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Dirk K. F. Meijer & Kornelia Ziegler. 1993. Biological Barriers to Protein Delivery. Biological Barriers to Protein Delivery 339 408 .
Dirk K. F. Meijer. 2011. Comprehensive Physiology. Comprehensive Physiology 717 758 .

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