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Xenobiotica
the fate of foreign compounds in biological systems
Volume 15, 1985 - Issue 8-9
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Original Article

Effects of benorylate and impacina on the metabolism of cultured hepatocytes

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Pages 743-749 | Published online: 30 Sep 2009

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M. J. GÓmez-LechÓn, A. Montoya, P. LÓpez, T. Donato, A. Larrauri & J. V. Castell. (1988) The potential use of cultured hepatocytes in predicting the hepatotoxicity of xenobiotics. Xenobiotica 18:6, pages 725-735.
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Articles from other publishers (17)

Roque Bort, M.José Gómez-Lechón, José V Castell & Ramiro Jover. (2004) Role of hepatocyte nuclear factor 3γ in the expression of human CYP2C genes. Archives of Biochemistry and Biophysics 426:1, pages 63-72.
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Ramiro Jover, Roque Bort, M.José Gómez-Lechón & José V Castell. (1998) Re-expression of C/EBPα induces CYP2B6, CYP2C9 and CYP2D6 genes in HepG2 cells. FEBS Letters 431:2, pages 227-230.
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JOSÉ V. CASTELL, MARÍA JOSÉ GÓMEZ-LECHÓN, XAVIER PONSODA & ROQUE BORT. 1997. In Vitro Methods in Pharmaceutical Research. In Vitro Methods in Pharmaceutical Research 375 410 .
ALISON E.M. VICKERS. 1997. In Vitro Methods in Pharmaceutical Research. In Vitro Methods in Pharmaceutical Research 103 127 .
X. Ponsoda, R. Bort, R. Jover, M.J. Gómez-lechón & J.V. Castell. (1995) Molecular mechanism of diclofenac hepatotoxicity: Association of cell injury with oxidative metabolism and decrease in ATP levels. Toxicology in Vitro 9:4, pages 439-444.
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Hironori KATOH, Mayumi TSUJI, Masako OKAZAKI & Katsuji OGUCHI. (1993) Coagulative and Fibrinolytic Activities in Primary Cultured Rat Hepatocytes Treated with Carbon Tetrachloride. The Showa University Journal of Medical Sciences 5:1, pages 51-62.
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M.T. Donato, F. Goethals, M.J. Gómez-Lechón, D. Deboyser, I. De Coster, M. Roberfroid & J.V. Castell. (1992) Toxicity of the antitumoral drug datelliptium in hepatic cells: Use of models in vitro for the prediction of toxicity in vivo. Toxicology in Vitro 6:4, pages 295-302.
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Sattar K. Abdul-Hussain & Harihara M. Mehendale. (1991) Studies on the age-dependent effects of galactosamine in primary rat hepatocyte cultures. Toxicology and Applied Pharmacology 107:3, pages 504-513.
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M.T. Donato, M.J. Gómez-Lechón & J.V. Castell. (1991) Rat hepatocytes cultured on a monkey kidney cell line: Expression of biotransformation and hepatic metabolic activities. Toxicology in Vitro 5:5-6, pages 435-438.
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X. Ponsoda, R. Jover, M.J. Gómez-Lechón, R. Fabra, R. Trullenque & J.V. Castell. (1991) The effects of buprenorphine on the metabolism of human hepatocytes. Toxicology in Vitro 5:3, pages 219-224.
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M. José Gómez-Lechón, Pilar López, Teresa Donato, Angel Montoya, Amparo Larrauri, Patricia Giménez, Ramón Trullenque, Ricardo Fabra & José V. Castell. (1990) Culture of human hepatocytes from small surgical liver biopsies. Biochemical characterization and comparison with in vivo. In Vitro Cellular & Developmental Biology 26:1, pages 67-74.
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Angel Montoya, Maria J. Gómez-Lechón & Jose V. Castell. (1989) Influence of branched-chain amino acid composition of culture media on the synthesis of plasma proteins by serum-free cultured rat hepatocytes. In Vitro Cellular & Developmental Biology 25:4.
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J. Masanet, M.J. Gómez-Lechón & J.V. Castell. (1988) Hepatic toxicity of paraquat in primary cultures of rat hepatocytes. Toxicology in Vitro 2:4, pages 275-282.
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John Dich, Constance Vind & Niels Grunnet. (1988) Long-term culture of hepatocytes: Effect of hormones on enzyme activities and metabolic capacity. Hepatology 8:1, pages 39-45.
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Angel Montoya & JoséV. Castell. (1987) Long-term storage of peroxidase-labelled immunoglobulins for use in enzyme immunoassay. Journal of Immunological Methods 99:1, pages 13-20.
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J.V. Castell, M.J. Gomez-L, V. Mirabet, M.A. Miranda & I.M. Morera. (1987) Photolytic Degradation of Benorylate: Effects of the Photoproducts on Cultured Hepatocytes. Journal of Pharmaceutical Sciences 76:5, pages 374-378.
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José V. Castell, M. A. José Gómez-Lechón, Miguel A. Miranda & Isabel M. Morera. (1987) Toxic effects of the photoproducts of chlorpromazine on cultured hepatocytes. Hepatology 7:2, pages 349-354.
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