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Xenobiotica
the fate of foreign compounds in biological systems
Volume 15, 1985 - Issue 8-9
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Original Article

Variability in the expression of xenobiotic-metabolizing enzymes during the growth cycle of rat hepatoma cells

Gisela Krupski Abteilung für Toxikologie, Gesellschaft für Strahlen-und Umweltforschung, D-8042, Neuherberg, FR, Germany
,
F. Kiefer Abteilung für Toxikologie, Gesellschaft für Strahlen-und Umweltforschung, D-8042, Neuherberg, FR, Germany
&
F. J. Wiebel Abteilung für Toxikologie, Gesellschaft für Strahlen-und Umweltforschung, D-8042, Neuherberg, FR, Germany
Pages 781-787 | Published online: 30 Sep 2009

Citations (9)

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Read on this site (2)

RM Phillips. (1998) Prospects for bioreductive drug development. Expert Opinion on Investigational Drugs 7:6, pages 905-928.
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H. Doostdar, A. Demoz, M. D. Burke, W. T. Melvin & M. H. Grant. (1990) Variation in drug-metabolizing enzyme activities during the growth of human Hep G2 hepatoma cells. Xenobiotica 20:4, pages 435-441.
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Articles from other publishers (7)

María J. Gómez‐Lechón, Teresa Donato, Ramiro Jover, Cristina Rodriguez, Xavier Ponsoda, Denize Glaise, José V. Castell & Christiane Guguen‐Guillouzo. (2002) Expression and induction of a large set of drug‐metabolizing enzymes by the highly differentiated human hepatoma cell line BC2. European Journal of Biochemistry 268:5, pages 1448-1459.
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L. R. Schwarz & F. J. Wiebel. 1993. Cytochrome P450. Cytochrome P450 399 413 .
Thomas Gebel & Edmund Maser. (1992) Characterization of carbonyl reducing activity in continuous cell lines of human and rodent origin. Biochemical Pharmacology 44:10, pages 2005-2012.
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Thomas Gebel, Edmund Maser & Karl J. Netter. (1991) The occurance of carbonyl reduction in continuous cell lines emphasizes the essentiality of this metabolic pathway. FEBS Letters 282:2, pages 359-362.
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Marina Roques, Denyse Bagrel, Jacques Magdalou & Gerard Siest. (1991) Expression of arylhydrocarbon hydroxylase, epoxide hydrolases, glutathione S-transferase and UDP-glucuronosyltransferases in H5-6 hepatoma cells. General Pharmacology: The Vascular System 22:4, pages 677-684.
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S.F. Roesch & F.J. Wiebel. (1990) Differential effects of 12-O-tetradecanoylphorbol 13-acetate on cytochrome P-450-dependent monooxygenase activities in rat hepatoma cells: Induction of P-450I and suppression of P-450II. Toxicology 61:2, pages 147-159.
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Margherita Ferro, Umberto M. Marinari, Anna M. Bassi & Giorgio Nanni. (2016) Biochemical Properties of Carcinogen-Metabolizing Enzymes in Cultured Hepatoma Cells. Toxicologic Pathology 15:1, pages 97-102.
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