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Xenobiotica
the fate of foreign compounds in biological systems
Volume 16, 1986 - Issue 10-11
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Original Article

The metabolism of aromatic amines

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Pages 933-955 | Published online: 30 Sep 2009

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Stephen C. Mitchell. (2020) N-acetyltransferase: the practical consequences of polymorphic activity in man. Xenobiotica 50:1, pages 77-91.
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Sajjad Damiri, Hamid Reza Pouretedal & Amin Heidari. (2016) Fabrication of a nanostructured TiO2/carbon nanotube composite electrode for voltammetric and impedimetric determination of NTO explosive in the water and soil samples. International Journal of Environmental Analytical Chemistry 96:11, pages 1059-1073.
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J. Devillers & E. Mombelli. (2010) Evaluation of the OECD QSAR Application Toolbox and Toxtree for estimating the mutagenicity of chemicals. Part 1. Aromatic amines. SAR and QSAR in Environmental Research 21:7-8, pages 753-769.
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B. Hedtke, Z. Gao, L.-J. Chen, W. M. Weber & K. J. Dix. (2008) Metabolism and disposition of [14C]5-amino--cresol in female F344 rats and B6C3F1 mice. Xenobiotica 38:2, pages 171-184.
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Tobias Weiss, Thomas Brüning & Hermann M. Bolt. (2007) Dephenylation of the Rubber Chemical N-Phenyl-2-Naphthylamine to Carcinogenic 2-Naphthylamine: A Classical Problem Revisited. Critical Reviews in Toxicology 37:7, pages 553-566.
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H. Major, J. Castro-Perez, J. K. Nicholson & I. D. Wilson. (2003) Detection of mono- and di-hexoses as metabolites of 4-bromoaniline using HPLC-TOF-MS/MS. Xenobiotica 33:8, pages 855-869.
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Gabriele Sabbioni & Christopher R. Jones. (2002) Biomonitoring of arylamines and nitroarenes. Biomarkers 7:5, pages 347-421.
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King‐Thom Chung. (2000) Mutagenicity and carcinogenicity of aromatic amines metabolically produced from Azo Dyes. Journal of Environmental Science and Health, Part C 18:1, pages 51-74.
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Dennis V. Parke. (1997) A History of Drug Metabolism in the United Kingdom. Drug Metabolism Reviews 29:3, pages 801-851.
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X.-Q. Wang, W. Seinen & W. De Wolf. (1994) Biotransformation of monochloroanilines in guppy, Poecilia reticulata. Xenobiotica 24:1, pages 59-69.
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S. Boeren, B. Tyrakowska, J. Vervoort, E. de Hoffman, K. Teunis, A. Van Veldhuizen & I. M. C. M. Rietjens. (1992) Rat liver microsomal metabolism of 2-halogenated 4-methylanilines. Xenobiotica 22:12, pages 1403-1423.
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Articles from other publishers (35)

Gabriele Sabbioni. (2017) Hemoglobin Adducts and Urinary Metabolites of Arylamines and Nitroarenes. Chemical Research in Toxicology 30:10, pages 1733-1766.
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Martine M. Ros, Manuela Gago-Dominguez, Katja K. H. Aben, H. Bas Bueno-de-Mesquita, Ellen Kampman, Sita H. Vermeulen & Lambertus A. Kiemeney. (2012) Personal hair dye use and the risk of bladder cancer: a case–control study from The Netherlands. Cancer Causes & Control 23:7, pages 1139-1148.
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Robert J. Turesky & Loic Le Marchand. (2011) Metabolism and Biomarkers of Heterocyclic Aromatic Amines in Molecular Epidemiology Studies: Lessons Learned from Aromatic Amines. Chemical Research in Toxicology 24:8, pages 1169-1214.
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David J. Snodin. (2010) Genotoxic Impurities: From Structural Alerts to Qualification. Organic Process Research & Development 14:4, pages 960-976.
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Birgitta Kütting, Thomas Göen, Ursula Schwegler, Hermann Fromme, Wolfgang Uter, Jürgen Angerer & Hans Drexler. (2009) Monoarylamines in the general population – A cross-sectional population-based study including 1004 Bavarian subjects. International Journal of Hygiene and Environmental Health 212:3, pages 298-309.
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Michael P. Cronin, Anthony I. Day & Lynne Wallace. (2007) Electrochemical remediation produces a new high-nitrogen compound from NTO wastewaters. Journal of Hazardous Materials 149:2, pages 527-531.
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Toby J. Athersuch, Jeremy K. Nicholson & Ian D. Wilson. (2007) Isotopic enrichment enhancement in metabonomic analysis of UPLC–MS data sets. Journal of Labelled Compounds and Radiopharmaceuticals 50:5-6, pages 303-307.
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M. D. Boudreau, H. W. Taylor, D. G. Baker & Jay C. Means. (2006) Dietary Exposure to 2-Aminoanthracene Induces Morphological and Immunocytochemical Changes in Pancreatic Tissues of Fisher-344 Rats. Toxicological Sciences 93:1, pages 50-61.
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Danuta Malejka-Giganti & Natalia Tretyakova. 2005. Carcinogenic and Anticarcinogenic Food Components. Carcinogenic and Anticarcinogenic Food Components.
Bernd Clement, Detlef Behrens, Juliane Amschler, Katrin Matschke, Stephanie Wolf & Antje Havemeyer. (2005) Reduction of sulfamethoxazole and dapsone hydroxylamines by a microsomal enzyme system purified from pig liver and pig and human liver microsomes. Life Sciences 77:2, pages 205-219.
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J. Gan, P. L. Skipper, M. Gago-Dominguez, K. Arakawa, R. K. Ross, M. C. Yu & S. R. Tannenbaum. (2004) Alkylaniline-Hemoglobin Adducts and Risk of Non-Smoking-Related Bladder Cancer. JNCI Journal of the National Cancer Institute 96:19, pages 1425-1431.
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Mary D. Boudreau, David G. BakerH. Wayne Taylor, Steven A. Barker & Jay C. Means. (2016) Suppression of Arylamine Toxicity in the Fischer-344 Rat Following Ingestion of a Complex Mixture. Toxicologic Pathology 29:3, pages 333-343.
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Tai-An chiang, wu pei-fen, Liao su ying, Li-Fang Wang & ying chin ko. (1999) Mutagenicity and aromatic amine content of fumes from heated cooking oils produced in Taiwan. Food and Chemical Toxicology 37:2-3, pages 125-134.
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Manon Vaal, Jan Tjalling van der Wal, Joop Hermens & Janneke Hoekstra. (1997) Pattern analysis of the variation in the sensitivity of aquatic species to toxicants. Chemosphere 35:6, pages 1291-1309.
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Jan F Van Bocxlaer, Karine M Clauwaert, Willy E Lambert & André P De Leenheer. (1997) Quantitative colorimetric determination of urinary p-aminophenol with an automated analyzer. Clinical Chemistry 43:4, pages 627-634.
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Kathrin Spiegel & Thomas Welsch. (1997) Monitoring degradation processes of explosives by HPLC analysis with UV- and amperometric detection. Fresenius Journal of Analytical Chemistry 357:3, pages 333-337.
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Marion Riffelmann, Gunther Müller, Wolfgang Schmieding, Walter Popp & Klaus Norpoth. (1996) Biomonitoring of urinary aromatic amines and arylamine hemoglobin adducts in exposed workers and nonexposed control persons. International Archives of Occupational and Environmental Health 68:1, pages 36-43.
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Ivonne M.C.M. Rietjens, Nicole H.P. Cnubben, Marjon van Haandel, Bozena Tyrakowska, Ans E.M.F. Soffers & Jacques Vervoort. (1995) Different metabolic pathways of 2,5-difluoronitrobenzene and 2,5-difluoroaminobenzene compared to molecular orbital substrate characteristics. Chemico-Biological Interactions 94:1, pages 49-72.
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Michael D. Corbett & Bernadette R. Corbett. 1995. Biodegradation of Nitroaromatic Compounds. Biodegradation of Nitroaromatic Compounds 151 182 .
Watze de Wolf, Bert Mast, Eddy S.E. Yedema, Willem Seinen & Joop L.M. Hermens. (1994) Kinetics of 4-chloroaniline in guppy, Poecilia reticulata. Aquatic Toxicology 28:1-2, pages 65-78.
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C. Nowak, K. Gleier, M. Christ, K. Gorzelniak & H.-B. Richter-Reichhelm. (1993) Effects of nitroso compounds and aromatic amines on fetal tracheal explants. Experimental and Toxicologic Pathology 45:2-3, pages 81-86.
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D. Wild. 1993. Advances in Mutagenesis Research. Advances in Mutagenesis Research 16 30 .
N.H.P. Cnubben, J. Vervoort, C. Veeger & I.M.C.M. Rietjens. (1992) Study on the regioselectivity and mechanism of the aromatic hydroxylation of monofluoroanilines. Chemico-Biological Interactions 85:2-3, pages 151-172.
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M. Kajbaf, O. Sepai, J.H. Lamb & S. Naylor. (1992) Identification of metabolites of 4,4'-diaminodiphenylmethane (methylene dianiline) using liquid chromatographic and mass spectrometric techniques. Journal of Chromatography B: Biomedical Sciences and Applications 583:1, pages 63-76.
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David C. McMillan, Timothy P. Bradshaw, Jack A. Hinson & David J. Jollow. (1991) Role of metabolites in propanil-induced hemolytic anemia. Toxicology and Applied Pharmacology 110:1, pages 70-78.
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M. Kajbaf, J.H. Lamb, S. Naylor, K. Pattichis & J.W. Gorrod. (1991) Identification of metabolites derived from the H2-receptor antagonist mifentidine using tandem mass spectrometry. Analytica Chimica Acta 247:2, pages 151-159.
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D. F. Houlihan, D. R. Livingstone & R. F. LeeDavid R. Livingstone. 1991. Advances in Comparative and Environmental Physiology. Advances in Comparative and Environmental Physiology 45 185 .
F F KadlubarP P FuH JungA U ShaikhF A Beland. (1990) The metabolic N-oxidation of carcinogenic arylamines in relation to nitrogen charge density and oxidation potential.. Environmental Health Perspectives 87, pages 233-236.
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Franca Viola, Giorgio Grosa, Maurizio Ceruti, Otto Caputo & Luigi Cattel. (1989) In vitro metabolism of azasqualene derivatives and their effects on aminopyrine N-demethylase activity in rat liver microsomes. Biochemical Pharmacology 38:15, pages 2497-2503.
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Michael Famulok & Gernot Boche. (1989) Formation ofN-(Deoxyguanosin-8-yl)aniline in the in vitro Reaction ofN-Acetoxyaniline with Deoxyguanosine and DNA. Angewandte Chemie International Edition in English 28:4, pages 468-469.
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Michael Famulok & Gernot Boche. (2006) N ‐(Desoxyguanosin‐8‐yl)anilin aus der in‐vitro‐Umsetzung von N ‐Acetoxyanilin mit Desoxyguanosin und DNA . Angewandte Chemie 101:4, pages 470-471.
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David W. Hein. (1988) Acetylator genotype and arylamine-induced carcinogenesis. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 948:1, pages 37-66.
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S.D. Jatoe, M. Kajbaf & J.W. Gorrod. (1988) High-performance liquid chromatography with on-line radioactivity monitoring for metabolic studies of 2- and 4-[14C]aminobiphenyls. Journal of Chromatography A 442, pages 394-400.
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