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Xenobiotica
the fate of foreign compounds in biological systems
Volume 16, 1986 - Issue 10-11
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Original Article

Role of intestinal flora in metabolism of agrochemicals conjugated with glutathione

J. E. Bakke Metabolism and Radiation Research Laboratory, Agricultural Research Service, US Department of Agriculture, Fargo, ND, 58105, USA
&
J.å Gustafsson Department of Medical Nutrition, Karolinska Institute, Huddinge University Hospital F69, S-141 86, Huddinge, Sweden
Pages 1047-1056 | Published online: 30 Sep 2009

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D. M. Dulik, J. K. Huwe, J. E. Bakke, M. S. Connors & C. Fenselau. (1992) Conjugation of polychlorinated agrochemical sulphoxides and sulphones by glutathione. Xenobiotica 22:3, pages 325-334.
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J. K. Huwe, V. J. Feil, J. E. Bakke & D. J. Mulford. (1991) Studies on the displacement of methylthio groups by glutathione. Xenobiotica 21:2, pages 179-191.
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C. B. Struble. (1991) In situ intestinal absorption of 2-chloro-N-isopropylacetanilide (propachlor) and non-biliary excretion of metabolites into the intestinal tract of rats, pigs and chickens. Xenobiotica 21:1, pages 85-95.
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P. W. Aschbacher & C. B. Struble. (1987) Evidence for involvement of non-biliary excretion into the intestines in the formation of methylsulphonyl-containing metabolites of 2-chloro-N-isopropylacetanilide (propachlor) by swine and rats. Xenobiotica 17:9, pages 1047-1055.
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Articles from other publishers (17)

Faizan Rashid, Veronika Dubinkina, Saeed Ahmad, Sergei Maslov & Joseph Maria Kumar Irudayaraj. (2023) Gut Microbiome-Host Metabolome Homeostasis upon Exposure to PFOS and GenX in Male Mice. Toxics 11:3, pages 281.
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Tine Rask Licht & Martin Iain Bahl. (2019) Impact of the gut microbiota on chemical risk assessment. Current Opinion in Toxicology 15, pages 109-113.
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Keng Po Lai, Alice Hoi-Man Ng, Hin Ting Wan, Aman Yi-Man Wong, Cherry Chi-Tim Leung, Rong Li & Chris Kong-Chu Wong. (2018) Dietary Exposure to the Environmental Chemical, PFOS on the Diversity of Gut Microbiota, Associated With the Development of Metabolic Syndrome. Frontiers in Microbiology 9.
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Xue Liang & Garret A. FitzGerald. (2017) Timing the Microbes: The Circadian Rhythm of the Gut Microbiome. Journal of Biological Rhythms 32:6, pages 505-515.
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Ian D. Wilson & Jeremy K. Nicholson. (2017) Gut microbiome interactions with drug metabolism, efficacy, and toxicity. Translational Research 179, pages 204-222.
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Ian D. Wilson & Jeremy K. Nicholson. 2015. Metabonomics and Gut Microbiota in Nutrition and Disease. Metabonomics and Gut Microbiota in Nutrition and Disease 323 341 .
Chunyan Zhao, Runbin Sun, Bei Cao, Shenghua Gu, Jieyu Zhao, Linsheng Liu, Xinwen Wang, Weibin Zha, Xiaoyi Yu, Wenjing Xiao, Yong Mao, Chun Ge, Jiaqi Ju, Lixiang Aa, Fei Fei, Yi Ding, Jiye Aa & Guangji Wang. (2013) An in vitro metabolic system of gut flora and the metabolism of ginsenoside Rg3 and cholic acid. European Journal of Drug Metabolism and Pharmacokinetics 39:2, pages 129-137.
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Jean-Pierre Cravedi & Daniel Zalko. 2011. Hormone-Disruptive Chemical Contaminants in Food. Hormone-Disruptive Chemical Contaminants in Food 93 114 .
Jeremy K. Nicholson, Elaine Holmes & Ian D. Wilson. (2005) Gut microorganisms, mammalian metabolism and personalized health care. Nature Reviews Microbiology 3:5, pages 431-438.
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Anne Hillenweck, Denis E. Corpet, James C. Killeen,, Myron Bliss, & Jean-Pierre Cravedi. (1999) Urinary and Biliary Metabolic Patterns of Chlorothalonil in Germ-Free and Conventional Rats. Journal of Agricultural and Food Chemistry 47:7, pages 2898-2903.
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Anne Hillenweck, Jean-Pierre Cravedi, Laurent Debrauwer, James C. KilleenJr.Jr., Myron BlissJr.Jr. & Denis E. Corpet. (1997) Chlorothalonil Biotransformation by Gastrointestinal Microflora:In VitroComparative Approach in Rat, Dog, and Human. Pesticide Biochemistry and Physiology 58:1, pages 34-48.
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Jerjang Chang, R.W. Chadwick, Joycelyn C. Allison, Yumiko O. Hayes, Detra L. Talley & Cari E. Autry. (2008) Microbial succession and intestinal enzyme activities in the developing rat. Journal of Applied Bacteriology 77:6, pages 709-718.
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M. Mikov. (1994) The metabolism of drugs by the gut flora. European Journal of Drug Metabolism and Pharmacokinetics 19:3, pages 201-207.
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MARTIN J. FETTMAN, ROSS N. BUTLER, ANTHONY J. McMICHAEL & IAN C. ROBERTS‐THOMSON. (2008) Metabolic phenotypes and colorectal neoplasia. Journal of Gastroenterology and Hepatology 6:1, pages 81-89.
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Peter F. Smith & Glenn F. Rush. 1990. Toxic Interactions. Toxic Interactions 87 114 .
M. Mikov, J. Caldwell, C.T. Dolphin & R.L. Smith. (1988) The role of intestinal microflora in the formation of the methylthio adduct metabolites of paracetamol. Biochemical Pharmacology 37:8, pages 1445-1449.
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. (1987) Communications. British Journal of Pharmacology 91:S1, pages 293P-510P.
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