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Xenobiotica
the fate of foreign compounds in biological systems
Volume 16, 1986 - Issue 12
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Original Article

Correlation between the metabolism of hexobarbital and aminopyrine in vivo in rats

M. Van Der Graaff Center for Bio-Pharmaceutical Sciences, Division of Pharmacology, University of Leiden, Sylvius Laboratories, P.O. Box 9503, 2300, RA Leiden, The Netherlands
,
N. P. E. Vermeulen Department of Pharmaco-Chemistry (Molecular Toxicology), Free University, De Boelelaan 1083, 1081, HV Amsterdam, The Netherlands
,
P. Heij Center for Bio-Pharmaceutical Sciences, Division of Pharmacology, University of Leiden, Sylvius Laboratories, P.O. Box 9503, 2300, RA Leiden, The Netherlands
,
H. De Bree Center for Bio-Pharmaceutical Sciences, Division of Pharmacology, University of Leiden, Sylvius Laboratories, P.O. Box 9503, 2300, RA Leiden, The Netherlands
&
D. D. Breimer Center for Bio-Pharmaceutical Sciences, Division of Pharmacology, University of Leiden, Sylvius Laboratories, P.O. Box 9503, 2300, RA Leiden, The Netherlands
Pages 1091-1096 | Received 12 Aug 1985, Accepted 18 May 1986, Published online: 30 Sep 2009

Citations (4)

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M. Van Der Graaff, N. P. E. Vermeulen & D. D. Breimer. (1988) Disposition of hexobarbital: 15 years of an intriguing model substrate. Drug Metabolism Reviews 19:2, pages 109-164.
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K. A. Bachmann, C. Yang, D. Jahn & J. Schwartz. (1988) The use of single sample clearance estimates to probe hepatic drug metabolism in rats. I. Xenobiotica 18:2, pages 151-159.
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Articles from other publishers (2)

H. Kraul, M. Pasanen, H. Sigusch, F. Stenbäck, S-S. Park, HV Gelboin & O. Pelkonen. (2016) Immunohistochemical properties of dipyrone-induced cytochromes P450 in rats. Human & Experimental Toxicology 15:1, pages 45-50.
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Silvia Menicagli, Annalisa Lippi, Marco Criscuoli & Pier Giovanni Gervasi. (1993) Effect of rociverine on P450-dependent monooxygenases and its N-deethylation metabolism in rat liver microsomes. Biochemical Pharmacology 45:5, pages 1097-1105.
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