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Xenobiotica
the fate of foreign compounds in biological systems
Volume 16, 1986 - Issue 12
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Original Article

Sulphoxide metabolites of thioridazine in man

A. S. Papadopoulos Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, UK
&
J. L. Crammer Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, UK
Pages 1097-1107 | Received 02 Sep 1985, Published online: 30 Sep 2009

Citations (13)

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B. L. Blake, R. L. Rose, R. B. Mailman, P. E. Levi & E. Hodgson. (1995) Metabolism of thioridazine by microsomal monooxygenases: relative roles of P450 and flavin-containing monooxygenase. Xenobiotica 25:4, pages 377-393.
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G. Lin, E. M. Hawes, G. McKay, E. D. Korchinski & K. K. Midha. (1993) Metabolism of piperidine-type phenothiazine antipsychotic agents. IV. Thioridazine in dog, man and rat. Xenobiotica 23:10, pages 1059-1074.
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G. Lin, E. M. Hawes, G. McKay, E. D. Korchinski & K. K. Midha. (1993) The metabolism of piperidine-type phenothiazine antipsychotic agents. III. Mescridazine in dog, human and rat. Xenobiotica 23:1, pages 37-52.
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G. Lin, E. M. Hawes, G. McKay, S. F. Cooper, E. D. Korchinski & K. K. Midha. (1993) The metabolism of piperidine-type phenothiazine antipsychotic agents. II. Sulforidazine in dog and human. Xenobiotica 23:1, pages 27-36.
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G. Lin, E. M. Hawes, G. McKay & K. K. Midha. (1992) The metabolism of piperidine-type phenothiazine antipsychotic agents. I. Sulforidazine in the rat. Xenobiotica 22:3, pages 303-317.
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Articles from other publishers (8)

So Hee Im, Myoung Joo Park, Hyewon Seo, Sung Heum Choi, Sang Kyum Kim & Sung-Hoon Ahn. (2014) Determination of mesoridazine by liquid chromatography–tandem mass spectrometry and its application to pharmacokinetic study in rats. Journal of Chromatography B 958, pages 117-123.
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M. L. Rao, M. Bagli, J. Fritze, G. Laux & P. König. 1998. Neuro-Psychopharmaka Ein Therapie-Handbuch. Neuro-Psychopharmaka Ein Therapie-Handbuch 307 354 .
R. Whelpton. 1997. Analytical Toxicology for Clinical, Forensic and Pharmaceutical Chemists. Analytical Toxicology for Clinical, Forensic and Pharmaceutical Chemists 451 480 .
Ge Lin, Ka-Wing Chu, Lyaquatali A. Damani & Edward M. Hawes. (1996) Identification of lactams as in vitro metabolites of piperidine-type phenothiazine antipsychotic drugs. Journal of Pharmaceutical and Biomedical Analysis 14:6, pages 727-738.
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John W. Hubbard, Barringer D. Marshall, Nuggehally R. Srinivas, Linda L. Bowen, John K. Cooper, Robert P. Liberman & K. K. Midha. (2012) Pharmacokinetics of Fenfluramine and Neuroleptics in the Treatment of Refractory Schizophrenia. Drug Investigation 4:2, pages 99-111.
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G. Lin, K. K. Midha & E. M. Hawes. (2009) Synthesis of the piperidinone metabolites of piperidine type phenothiazine antipsychotic drugs via ruthenium tetroxide oxidation . Journal of Heterocyclic Chemistry 28:2, pages 215-219.
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T. Mohammad, E. M. Hawes, G. McKay & K. K. Midha. (1990) An improved synthesis of dideuterated thioridazine with the label in the piperidine ring. Journal of Labelled Compounds and Radiopharmaceuticals 28:9, pages 1087-1092.
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B.S. Chakraborty, E.M. Hawes, G. McKay, J.W. Hubbard, E.D. Korchinski, K.K. Midha, M.G. Choc & W.T. Robinson. (1988) S-OXIDATION OF THIORIDAZINE TO PSYCHOACTIVE METABOLITES: AN ORAL DOSE-PROPORTIONALITY STUDY IN HEALTHY VOLUNTEERS. Drug Metabolism and Drug Interactions 6:3-4.
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