Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 16, 1986 - Issue 2
59
Views
54
CrossRef citations to date
0
Altmetric
Original Article

The microbial metabolism of condensed (+)-catechins by rat-caecal microflora

&
Pages 99-107 | Received 19 Oct 1984, Published online: 30 Sep 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Michael N. Clifford, Laurence J. King, Asimina Kerimi, Maria Gema Pereira-Caro & Gary Williamson. (2022) Metabolism of phenolics in coffee and plant-based foods by canonical pathways: an assessment of the role of fatty acid β-oxidation to generate biologically-active and -inactive intermediates. Critical Reviews in Food Science and Nutrition 0:0, pages 1-58.
Read now
M. N. Clifford, E. L. Copeland, J. P. Bloxsidge & L. A. Mitchell. (2000) Hippuric acid as a major excretion product associated with black tea consumption. Xenobiotica 30:3, pages 317-326.
Read now

Articles from other publishers (52)

Imre Hegedüs, Kitti Andreidesz, József L. Szentpéteri, Zoltán Kaleta, László Szabó, Krisztián Szigeti, Balázs Gulyás, Parasuraman Padmanabhan, Ferenc Budan & Domokos Máthé. (2022) The Utilization of Physiologically Active Molecular Components of Grape Seeds and Grape Marc. International Journal of Molecular Sciences 23:19, pages 11165.
Crossref
Filomena Nazzaro, Florinda Fratianni, Vincenzo De Feo, Alberto Battistelli, Adriano Gomes Da Cruz & Raffaele Coppola. 2020. Probiotic and Prebiotics in Foods: Challenges, Innovations and Advances. Probiotic and Prebiotics in Foods: Challenges, Innovations and Advances 35 89 .
Pedro Mena, Letizia Bresciani, Nicoletta Brindani, Iziar A. Ludwig, Gema Pereira-Caro, Donato Angelino, Rafael Llorach, Luca Calani, Furio Brighenti, Michael N. Clifford, Chris I. R. Gill, Alan Crozier, Claudio Curti & Daniele Del Rio. (2019) Phenyl-γ-valerolactones and phenylvaleric acids, the main colonic metabolites of flavan-3-ols: synthesis, analysis, bioavailability, and bioactivity. Natural Product Reports 36:5, pages 714-752.
Crossref
Susana Chamorro, Carlos Romero, Agustín Brenes, Fernando Sánchez-Patán, Begoña Bartolomé, Agustín Viveros & Ignacio Arija. (2019) Impact of a sustained consumption of grape extract on digestion, gut microbial metabolism and intestinal barrier in broiler chickens. Food & Function 10:3, pages 1444-1454.
Crossref
Carine Le Bourvellec, Priscilla Bagano Vilas Boas, Pascale Lepercq, Sophie Comtet-Marre, Pauline Auffret, Philippe Ruiz, Romain Bott, Catherine Renard, Claire Dufour, Jean-Marc Chatel & Pascale Mosoni. (2019) Procyanidin—Cell Wall Interactions within Apple Matrices Decrease the Metabolization of Procyanidins by the Human Gut Microbiota and the Anti-Inflammatory Effect of the Resulting Microbial Metabolome In Vitro. Nutrients 11:3, pages 664.
Crossref
Siddhi Bagwe-Parab, Ginpreet Kaur, Harpal Singh Buttar & Hardeep Singh Tuli. 2019. Current Aspects of Flavonoids: Their Role in Cancer Treatment. Current Aspects of Flavonoids: Their Role in Cancer Treatment 125 137 .
Sen Lin, Qing Li, Bao Yang, Xuewu Duan, Mingwei Zhang, John Shi & Yueming Jiang. (2016) Transformation of Litchi Pericarp-Derived Condensed Tannin with Aspergillus awamori. International Journal of Molecular Sciences 17:7, pages 1067.
Crossref
Myron Gross. 2016. Grapes and Health. Grapes and Health 27 52 .
Filomena Nazzaro, Florinda Fratianni, Antonio d'Acierno & Raffaele Coppola. 2015. Advances in Food Biotechnology. Advances in Food Biotechnology 335 350 .
Zhen-zhen Ge, Xiao-qian Dong, Wei Zhu, Ying Zhang & Chun-mei Li. (2015) Metabolites and Changes in Antioxidant Activity of A-Type and B-Type Proanthocyanidin Dimers after Incubation with Rat Intestinal Microbiota. Journal of Agricultural and Food Chemistry 63:41, pages 8991-8998.
Crossref
Juan Xiao, Shuyi Li, Yong Sui, Qian Wu, Xiaopeng Li, Bijun Xie, Mingwei Zhang & Zhida Sun. (2014) Lactobacillus casei-01 Facilitates the Ameliorative Effects of Proanthocyanidins Extracted from Lotus Seedpod on Learning and Memory Impairment in Scopolamine-Induced Amnesia Mice. PLoS ONE 9:11, pages e112773.
Crossref
Toshihiko Shoji. 2014. Polyphenols in Human Health and Disease. Polyphenols in Human Health and Disease 339 351 .
Dongjie Wang, Barbara A Williams, Mario G Ferruzzi & Bruce R D'Arcy. (2012) Different concentrations of grape seed extract affect in vitro starch fermentation by porcine small and large intestinal inocula . Journal of the Science of Food and Agriculture 93:2, pages 276-283.
Crossref
. 2013. Principles and Practice of Phytotherapy. Principles and Practice of Phytotherapy 17 82 .
Fernando Sánchez-Patán, Raquel Tabasco, María Monagas, Teresa Requena, Carmen Peláez, M. Victoria Moreno-Arribas & Begoña Bartolomé. (2012) Capability of Lactobacillus plantarum IFPL935 To Catabolize Flavan-3-ol Compounds and Complex Phenolic Extracts. Journal of Agricultural and Food Chemistry 60:29, pages 7142-7151.
Crossref
C. Muñoz-González, M.V. Moreno-Arribas, J.J. Rodríguez-Bencomo, C. Cueva, P.J. Martín Álvarez, B. Bartolomé & M.A. Pozo-Bayón. (2012) Feasibility and application of liquid–liquid extraction combined with gas chromatography–mass spectrometry for the analysis of phenolic acids from grape polyphenols degraded by human faecal microbiota. Food Chemistry 133:2, pages 526-535.
Crossref
Sebastian Rzeppa, Katharina Bittner, Susanne Döll, Sven Dänicke & Hans‐Ulrich Humpf. (2012) Urinary excretion and metabolism of procyanidins in pigs. Molecular Nutrition & Food Research 56:4, pages 653-665.
Crossref
Fernando Sánchez-Patán, Carolina Cueva, Maria Monagas, Gemma E. Walton, Glenn R. Gibson, Pedro J. Martín-Álvarez, M. Victoria Moreno-Arribas & Begoña Bartolomé. (2012) Gut microbial catabolism of grape seed flavan-3-ols by human faecal microbiota. Targetted analysis of precursor compounds, intermediate metabolites and end-products. Food Chemistry 131:1, pages 337-347.
Crossref
Gary Williamson & Michael N. Clifford. (2010) Colonic metabolites of berry polyphenols: the missing link to biological activity?. British Journal of Nutrition 104:S3, pages S48-S66.
Crossref
Stavroula Stoupi, Gary Williamson, J. Warren Drynan, Denis Barron & Michael N. Clifford. (2010) Procyanidin B2 catabolism by human fecal microflora: Partial characterization of ‘dimeric’ intermediates. Archives of Biochemistry and Biophysics 501:1, pages 73-78.
Crossref
Stavroula Stoupi, Gary Williamson, J. Warren Drynan, Denis Barron & Michael N. Clifford. (2010) A comparison of the in vitro biotransformation of (–)‐epicatechin and procyanidin B2 by human faecal microbiota . Molecular Nutrition & Food Research 54:6, pages 747-759.
Crossref
Sonia De Pascual-Teresa, Diego A. Moreno & Cristina García-Viguera. (2010) Flavanols and Anthocyanins in Cardiovascular Health: A Review of Current Evidence. International Journal of Molecular Sciences 11:4, pages 1679-1703.
Crossref
Maria Monagas, Mireia Urpi-Sarda, Fernando Sánchez-Patán, Rafael Llorach, Ignacio Garrido, Carmen Gómez-Cordovés, Cristina Andres-Lacueva & Begoña Bartolomé. (2010) Insights into the metabolism and microbial biotransformation of dietary flavan-3-ols and the bioactivity of their metabolites. Food & Function 1:3, pages 233.
Crossref
Laure Poquet, Michael N Clifford & Gary Williamson. 2009. Plant Phenolics and Human Health. Plant Phenolics and Human Health 51 89 .
Mireia Urpi-Sarda, María Monagas, Nasiruddin Khan, Rafael Llorach, Rosa Ma Lamuela-Raventós, Olga Jáuregui, Ramón Estruch, María Izquierdo-Pulido & Cristina Andrés-Lacueva. (2009) Targeted metabolic profiling of phenolics in urine and plasma after regular consumption of cocoa by liquid chromatography–tandem mass spectrometry. Journal of Chromatography A 1216:43, pages 7258-7267.
Crossref
María V. Selma, Juan C. Espín & Francisco A. Tomás-Barberán. (2009) Interaction between Phenolics and Gut Microbiota: Role in Human Health. Journal of Agricultural and Food Chemistry 57:15, pages 6485-6501.
Crossref
Maaike M. Appeldoorn, Jean-Paul Vincken, Anna-Marja Aura, Peter C. H. Hollman & Harry Gruppen. (2009) Procyanidin Dimers Are Metabolized by Human Microbiota with 2-(3,4-Dihydroxyphenyl)acetic Acid and 5-(3,4-Dihydroxyphenyl)-γ-valerolactone as the Major Metabolites. Journal of Agricultural and Food Chemistry 57:3, pages 1084-1092.
Crossref
F.A. Tomás-Barberán, A. Gil-Izquierdo & D.A. Moreno. 2009. Designing Functional Foods. Designing Functional Foods 194 229 .
Anna-Marja Aura. (2008) Microbial metabolism of dietary phenolic compounds in the colon. Phytochemistry Reviews 7:3, pages 407-429.
Crossref
Laure Poquet, Michael N. Clifford & Gary Williamson. (2008) Effect of dihydrocaffeic acid on UV irradiation of human keratinocyte HaCaT cells. Archives of Biochemistry and Biophysics 476:2, pages 196-204.
Crossref
Chung S. Yang, Shengmin Sang, Joshua D. Lambert & Mao-Jung Lee. (2008) Bioavailability issues in studying the health effects of plant polyphenolic compounds. Molecular Nutrition & Food Research.
Crossref
Laure Poquet, Michael N. Clifford & Gary Williamson. (2008) Investigation of the metabolic fate of dihydrocaffeic acid. Biochemical Pharmacology 75:5, pages 1218-1229.
Crossref
Bastian Knaup, Kathrin Kahle, Thomas Erk, Anagnostis Valotis, Wolfgang Scheppach, Peter Schreier & Elke Richling. (2007) Human intestinal hydrolysis of phenol glycosides – a study with quercetin andp-nitrophenol glycosides using ileostomy fluid. Molecular Nutrition & Food Research 51:11, pages 1423-1429.
Crossref
Mbang A. Owolabi, Herbert A. B. Coker & Smith I. Jaja. (2007) Flavonoid metabolites in urine after oral administration of aqueous extract of Persea americana to rats. Journal of Natural Medicines 61:2, pages 200-204.
Crossref
Max Bingham. 2006. Gastrointestinal Microbiology. Gastrointestinal Microbiology 155 168 .
Tanja Grimm, Angelika Schäfer & Petra Högger. (2004) Antioxidant activity and inhibition of matrix metalloproteinases by metabolites of maritime pine bark extract (pycnogenol). Free Radical Biology and Medicine 36:6, pages 811-822.
Crossref
Yumiko Nakamura & Yasuhide Tonogai. (2003) Metabolism of Grape Seed Polyphenol in the Rat. Journal of Agricultural and Food Chemistry 51:24, pages 7215-7225.
Crossref
Marie-Paule Gonthier, Jennifer L Donovan, Odile Texier, Catherine Felgines, Christian Remesy & Augustin Scalbert. (2003) Metabolism of dietary procyanidins in rats. Free Radical Biology and Medicine 35:8, pages 837-844.
Crossref
Laurent Y Rios, Marie-Paule Gonthier, Christian Rémésy, Isabelle Mila, Catherine Lapierre, Sheryl A Lazarus, Gary Williamson & Augustin Scalbert. (2003) Chocolate intake increases urinary excretion of polyphenol-derived phenolic acids in healthy human subjects,,. The American Journal of Clinical Nutrition 77:4, pages 912-918.
Crossref
Marie-Paule Gonthier, Jennifer L. Donovan, Claudine Manach, Christine Morand, Christian Rémésy, Augustin Scalbert, Véronique Cheynier, Isabelle Mila & Catherine Lapierre. (2003) Microbial Aromatic Acid Metabolites Formed in the Gut Account for a Major Fraction of the Polyphenols Excreted in Urine of Rats Fed Red Wine Polyphenols. The Journal of Nutrition 133:2, pages 461-467.
Crossref
Kelly E Heim, Anthony R Tagliaferro & Dennis J Bobilya. (2002) Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships. The Journal of Nutritional Biochemistry 13:10, pages 572-584.
Crossref
Jennifer L. Donovan, Adam Lee, Claudine Manach, Laurent Rios, Christine Morand, Augustin Scalbert & Christian Rémésy. (2007) Procyanidins are not bioavailable in rats fed a single meal containing a grapeseed extract or the procyanidin dimer B 3 . British Journal of Nutrition 87:4, pages 299-306.
Crossref
Stephanie Deprez, Isabelle Mila, Jean-François Huneau, Daniel Tome & Augustin Scalbert. (2001) Transport of Proanthocyanidin Dimer, Trimer, and Polymer Across Monolayers of Human Intestinal Epithelial Caco-2 Cells. Antioxidants & Redox Signaling 3:6, pages 957-967.
Crossref
Rocío Abia & Stephen C Fry. (2001) Degradation and metabolism of 14 C‐labelled proanthocyanidins from carob ( Ceratonia siliqua ) pods in the gastrointestinal tract of the rat . Journal of the Science of Food and Agriculture 81:12, pages 1156-1165.
Crossref
Stéphanie Déprez, Isabelle Mila, Catherine Lapierre, Christophe Brezillon, Sylvie Rabot, Catherine Philippe & Augustin Scalbert. (2000) Polymeric Proanthocyanidins Are Catabolized by Human Colonic Microflora into Low-Molecular-Weight Phenolic Acids. The Journal of Nutrition 130:11, pages 2733-2738.
Crossref
Celestino Santos-Buelga & Augustin Scalbert. (2000) Proanthocyanidins and tannin-like compounds - nature, occurrence, dietary intake and effects on nutrition and health. Journal of the Science of Food and Agriculture 80:7, pages 1094-1117.
Crossref
Francisco A Tom�s-Barber�n & Michael N Clifford. (2000) Dietary hydroxybenzoic acid derivatives - nature, occurrence and dietary burden. Journal of the Science of Food and Agriculture 80:7, pages 1024-1032.
Crossref
Augustin Scalbert, Stéphanie Déprez, Isabelle Mila, Anne‐Marie Albrecht, Jean‐François Huneau & Sylvie Rabot. (2008) Proanthocyanidins and human health: Systemic effects and local effects in the gut. BioFactors 13:1-4, pages 115-120.
Crossref
Jörg Heilmann & Irmgard Merfort. (2006) Aktueller Kenntnisstand zum Metabolismus von Flavonoiden II. Resorption und Metabolismus von Flavonen, Flavanonen, Flavanen, Proanthocyanidinen und Isoflavonoiden. Pharmazie in unserer Zeit 27:4, pages 173-183.
Crossref
R. A. Perez-Maldonado & B. W. Norton. (2007) The effects of condensed tannins from Desmodium intortum and Calliandra calothyrsus on protein and carbohydrate digestion in sheep and goats . British Journal of Nutrition 76:4, pages 515-533.
Crossref
R. A. Perez-Maldonado & B. W. Norton. (2007) Digestion of 14 C-labelled condensed tannins from Desmodium intortum in sheep and goats . British Journal of Nutrition 76:4, pages 501-513.
Crossref
P.G. Pietta, C. Gardana, P.L. Mauri, R. Maffei-Facino & M. Carini. (1995) Identification of flavonoid metabolites after oral administration to rats of a Ginkgo biloba extract. Journal of Chromatography B: Biomedical Sciences and Applications 673:1, pages 75-80.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.