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Xenobiotica
the fate of foreign compounds in biological systems
Volume 16, 1986 - Issue 2
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Original Article

Disposition and biotransformation of 14C-etodolac in man

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Pages 153-166 | Received 01 Feb 1985, Published online: 30 Sep 2009

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Mehmet Emrah Yaman, Omer Faruk Kocak, Alptug Atila, Yucel Kadioglu, Busra Diyarbakir & Zekai Halici. (2018) Rapid and sensitive UPLC-MS/MS method for the determination of etodolac in small-volume rat plasma: Application to rat real samples. Journal of Liquid Chromatography & Related Technologies 41:9, pages 474-480.
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K. Tougou, H. Gotou, Y. Ohno & A. Nakamura. (2004) Stereoselective glucuronidation and hydroxylation of etodolac by UGT1A9 and CYP2C9 in man. Xenobiotica 34:5, pages 449-461.
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Dilek Dogrukol-Ak, Özlem Banu Kutluk, Muzaffer Tunçel & Hassan Y. Aboul-Enein. (2001) CAPILLARY ELECTROPHORETIC METHOD FOR THE DETERMINATION OF ETODOLAC IN PHARMACEUTICAL TABLET FORMULATION. Journal of Liquid Chromatography & Related Technologies 24:6, pages 773-780.
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Articles from other publishers (27)

Carolina de Miranda Silva, Adriana Rocha, Eduardo Tozatto, Lucienir Maria da Silva, Eduardo Antônio Donadi, Teresa Dalla Costa, Vera Lucia Lanchote, Stephan Schmidt & Jürgen B. Bulitta. (2017) Development of an Enantioselective and Biomarker-Informed Translational Population Pharmacokinetic/Pharmacodynamic Model for Etodolac. The AAPS Journal 19:6, pages 1814-1825.
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Yin Zhou, Paula Hertel & Jennifer Cu. (2017) Case 5: Large Amounts of Urine Bilirubin on Urine Dipstick in a 14-year-old Girl. Pediatrics In Review 38:9, pages 440-440.
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P. Mehta, M. Lukacs & S. M. Abraham. (2011) Normal in the blood, abnormal in the urine. QJM 105:10, pages 1001-1002.
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Fumihiro Nakamori, Yoichi Naritomi, Ken-ichi Hosoya, Hiroyuki Moriguchi, Kazuhiro Tetsuka, Takako Furukawa, Keitaro Kadono, Katsuhiro Yamano, Shigeyuki Terashita & Toshio Teramura. (2012) Quantitative Prediction of Human Intestinal Glucuronidation Effects on Intestinal Availability of UDP-Glucuronosyltransferase Substrates Using In Vitro Data. Drug Metabolism and Disposition 40:9, pages 1771-1777.
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. (2008) Bioequivalence of Etodin Capsule to Kuhnillodin Capsule (Etodolac 200 mg). Journal of Korean Pharmaceutical Sciences 38:6, pages 421-427.
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Hyun-Soo Lee, Il-Mo Kang, Heon-Woo Lee, Ji-Hyung Seo, Ju-Hee Ryu, Sang-Jun Choi, Myung-Jae Lee, Seo-Young Jeong, Young-Wuk Cho & Kyung-Tae Lee. (2008) Development and validation of a high performance liquid chromatography–tandem mass spectrometry for the determination of etodolac in human plasma. Journal of Chromatography B 863:1, pages 158-162.
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Audrey Griffin. (2006) Diagnostic challenges from your case files. Journal of the American Academy of Physician Assistants 19:11, pages 70.
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Ketan P. Shah, Kavita Gumbhir-Shah & Harry G. Brittain. 2002. 105 147 .
Dirk B Strickmann & Gottfried Blaschke. (2001) Isolation of an unknown metabolite of the non-steroidal anti-inflammatory drug etodolac and its identification as 5-hydroxy etodolac. Journal of Pharmaceutical and Biomedical Analysis 25:5-6, pages 977-984.
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Joseph P. Boni, Joan M. Korthbradley, Lyette S. Richards, Soong T. Chiang, David R. Hicks & Leslie Z. Benet. (2000) Chiral Bioequivalence. Clinical Pharmacokinetics 39:6, pages 459-469.
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Joseph P. Boni, Joan M. Korth-Bradley, Patrick Martin, Donna K. Simcoe, Lyette S. Richards, Robert Rennebohm & Philip D. Walson. (1999) Pharmacokinetics of etodolac in patients with stable juvenile rheumatoid arthritis. Clinical Therapeutics 21:10, pages 1715-1724.
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Joseph Boni, Joan Korth‐Bradley, Karen McGoldrick, Alan Appel & Stephen Cooper. (2013) Pharmacokinetic and Pharmacodynamic Action of Etodolac in Patients after Oral Surgery. The Journal of Clinical Pharmacology 39:7, pages 729-737.
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John de Kanel, William E. Vickery & Francis X. Diamond. (1998) Simultaneous analysis of 14 non-steroidal anti-inflammatory drugs in human serum by electrospray ionization-tandem mass spectrometry without chromatography. Journal of the American Society for Mass Spectrometry 9:3, pages 255-257.
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R. Wennig. 1996. Human Toxicology. Human Toxicology 25 236 .
Claudio Giachetti, Alessandro Assandri, Giovanni Zanolo & Emilio Brembilla. (2005) Gas chromatography–mass spectrometry determination of etodolac in human plasma following single epicutaneous administration. Biomedical Chromatography 8:4, pages 180-183.
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M. Kreher. (1994) 6. Frühjahrstagung der Deutschen Pharmazeutischen Gesellschaft („Doktorandentagung”). Pharmazie in Unserer Zeit 23:4, pages 230-252.
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U. Becker-Scharfenkamp & G. Blaschke. (1993) Evaluation of the stereoselective metabolism of the chiral analgesic drug etodolac by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 621:2, pages 199-207.
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Dion R. Brocks, Fakhreddin Jamali, Anthony S. Russell & Kenneth J. Skeith. (2013) The Stereoselective Pharmacokinetics of Etodolac in Young and Elderly Subjects, and After Cholecystectomy. The Journal of Clinical Pharmacology 32:11, pages 982-989.
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. (2006) Kurzreferate der Vorträge. Pharmazie in unserer Zeit 21:3, pages 111-134.
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Dion R. Brocks & Fakhreddin Jamali. (1991) Enantioselective Pharmacokinetics of Etodolac in the Rat: Tissue Distribution, Tissue Binding, and In Vitro Metabolism. Journal of Pharmaceutical Sciences 80:11, pages 1058-1061.
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N. Zvaifler. (1989) A review of the antiarthritic efficacy and safety of etodolac. Clinical Rheumatology 8:S1, pages 43-53.
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D. C. Brater & K. C. Lasseter. (1989) Profile of etodolac: Pharmacokinetic evaluation in special populations. Clinical Rheumatology 8:S1, pages 25-35.
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D. Dvornik & D. K. H. Lee. (1989) Theoretical mechanism for the gastrointestinal safety of etodolac: Selective sparing of cytoprotective prostaglandins. Clinical Rheumatology 8:S1, pages 16-24.
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F. Jamali, R. Mehvar, C. Lemko & O. Eradiri. (1988) Application of a Stereospecific High-Performance Liquid Chromatography Assay to a Pharmacokinetic Study of Etodolac Enantiomers in Humans. Journal of Pharmaceutical Sciences 77:11, pages 963-966.
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Leslie G. Humber. (2006) Etodolac: The chemistry, pharmacology, metabolic disposition, and clinical profile of a novel anti‐inflammatory pyranocarboxylic acid. Medicinal Research Reviews 7:1, pages 1-28.
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Robert J. Linhardt, C. Cavazza, I. Chibata, T. Tosa, T. Mori, M. Fujimura, B. D. Ensley, M. Fujiwara, A. Fujiwara, C. Miyamoto, I. Goldberg, B. Stieglitz, T. Goodhue, G. C. Kydd, H. Foster, C. A. McCombs, I. J. Higgins, F. F. Hill, J. Schindler, R. Schmid, W. Preuss, A. Struve, J. H. Hsieh, S. J. Barer, P. C. Maxwell, Y. Imada, T. Osozawa, Y. Morimoto, M. Kinoshita, J. C. Knight, M. G. Wovcha, L. A. Kominek, H. J. Wolf, V. Krasnobajew, M. R. Kula, W. Hummel, H. Schutte, W. Leuchtenberger, P. Kurtzman, R. J. Bothast, J. E. VanCauwenberge, G. Manecke, U. Klussman, W. J. Marsheck, J. Jiu, P. T. Wang, J. E. McCullough, T. G. Mitchell, A. G. Barnes, J. S. Jackson, P. C. Bevan, T. Oki, A. Yoshimoto, Y. Matsuzawa, T. Inui, T. Takeuchi, H. Umezawa, K. Kouno, Sawada, Haruji, H. Taguchi, R. J. Seely, C. J. Sih, T. Sonoyama, B. Kageyama, T. Honjo, G. Teichmuller, J. Rabe, H. Henkel, A. Terahara, M. Tanaka, A. Teraham, J. R. Turner, V. M. Krupinski, D. S. Fukuda, R. H. Baltz, N. Udvardy, P. Cserey, I. Bartho, G. Hantos, M. Trinn, Z. Vida, J. Szejtli, E. Stadler, A. Szoke, I. Habon, E. Bal, M. E. Czurda, A. Weber, M. Kennecke, R. Müller, C. B. Biggs, J. G. Zeikus & R. J. Lamed. (1986) Patents and literature. Applied Biochemistry and Biotechnology 13:3, pages 249-262.
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