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Xenobiotica
the fate of foreign compounds in biological systems
Volume 17, 1987 - Issue 4
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Original Article

Species specificity in the metabolism of nabilone. Relationship between toxicity and metabolic routes

H. R. Sullivan Department of Drug Disposition, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, 46285, USA
,
G. K. Hanasono Department of Drug Disposition, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, 46285, USA
,
W. M. Miller Department of Drug Disposition, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, 46285, USA
&
P. G. Wood Department of Drug Disposition, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, 46285, USA
Pages 459-468 | Received 27 Feb 1986, Published online: 30 Sep 2009

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Mario Pellegatti. (2012) Preclinical in vivo ADME studies in drug development: a critical review. Expert Opinion on Drug Metabolism & Toxicology 8:2, pages 161-172.
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Mario Pellegatti & Sabrina Pagliarusco. (2011) Drug and metabolite concentrations in tissues in relationship to tissue adverse findings: a review. Expert Opinion on Drug Metabolism & Toxicology 7:2, pages 137-146.
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I. Midgley, K. Fitzpatrick, S. J. Wright, B. A. John, A. J. Peard, R. M. Major, J. D. Holding, A. McBurney, R. Anacardio, R. Novellini & M. P. Ferrari. (2006) Species differences in the pharmacokinetics and metabolism of reparixin in rat and dog. Xenobiotica 36:5, pages 419-440.
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Franjo Grotenhermen. (2003) Clinical Pharmacokinetics of Cannabinoids. Journal of Cannabis Therapeutics 3:1, pages 3-51.
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Peter Dogterom, Gerhard Zbinden & Gerd K. Reznik. (1992) Cardiotoxicity of Vasodilators and Positive Inotropic/Vasodilating Drugs in Dogs: An Overview. Critical Reviews in Toxicology 22:3-4, pages 203-241.
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D. A. Smith, M. J. Humphrey & C. Charuel. (1990) Design of toxicokinetic studies. Xenobiotica 20:11, pages 1187-1199.
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Articles from other publishers (7)

Katarina Černe. (2020) Toxicological properties of Δ 9 -tetrahydrocannabinol and cannabidiol . Archives of Industrial Hygiene and Toxicology 71:1, pages 1-11.
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Dana Vaughn, Justyna Kulpa & Lina Paulionis. (2020) Preliminary Investigation of the Safety of Escalating Cannabinoid Doses in Healthy Dogs. Frontiers in Veterinary Science 7.
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Marcus S. Delatte. 2019. Advanced Issue Resolution in Safety Pharmacology. Advanced Issue Resolution in Safety Pharmacology 203 223 .
Simon Authier, Marcus S. Delatte, Mary-Jeanne Kallman, Joanne Stevens & Carrie Markgraf. (2016) EEG in non-clinical drug safety assessments: Current and emerging considerations. Journal of Pharmacological and Toxicological Methods 81, pages 274-285.
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William J. Wheeler. (2007) Isotopic chemistry at Eli Lilly and Company – a look back at the past fifty years. Journal of Labelled Compounds and Radiopharmaceuticals 50:9-10, pages 811-817.
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Franjo Grotenhermen. (2003) Pharmacokinetics and Pharmacodynamics of Cannabinoids. Clinical Pharmacokinetics 42:4, pages 327-360.
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J. M. Mayer & B. Testa. 1994. Pharmacokinetics of Drugs. Pharmacokinetics of Drugs 209 231 .

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