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Xenobiotica

the fate of foreign compounds in biological systems

Volume 17, 1987 - Issue 4

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Original Article

The induction of ω and β-oxidation of fatty acids and effect on α_2u globulin content in the liver and kidney of rats administered 2, 2, 4-trimethylpentane

E. A. Lock Imperial Chemical Industries PLC, Central Toxicology Laboratory, Alderley Park, Nr Macclesfield, Cheshire, SK, 10 4TJ, UK

M. D. Stonard Imperial Chemical Industries PLC, Central Toxicology Laboratory, Alderley Park, Nr Macclesfield, Cheshire, SK, 10 4TJ, UK

C. R. Elcombe Imperial Chemical Industries PLC, Central Toxicology Laboratory, Alderley Park, Nr Macclesfield, Cheshire, SK, 10 4TJ, UK

Pages 513-522 | Received 03 Feb 1986, Published online: 30 Sep 2009

Cite this article
https://doi.org/10.3109/00498258709043958

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Ijaz S. Jamall & Calvin C. Willhite. (2008) Is benzene exposure from gasoline carcinogenic?. J. Environ. Monit. 10:2, pages 176-187.
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Monica A. Valentovic, Napoleon Alejandro, A. Betts Carpenter, Patrick I. Brown & Kenneth Ramos. (2006) Streptozotocin (STZ) diabetes enhances benzo(α)pyrene induced renal injury in Sprague Dawley rats. Toxicology Letters 164:3, pages 214-220.
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Masao HAMAMURAAkihiko HIROSE, Eiichi KAMATA, Koshiro KATOKUEmiko KUWASAKITakafumi OSHIKATAYutaka NAKAHARAMakoto EMA & Ryuichi HASEGAWA. (2006) SEMI-QUANTITATIVE IMMUNOHISTOCHEMICAL ANALYSIS OF MALE RAT-SPECIFIC α2u-GLOBULIN ACCUMULATION FOR CHEMICAL TOXICITY EVALUATION. The Journal of Toxicological Sciences 31:1, pages 35-47.
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Ana Maria Cuervo, Heinz Hildebrand, Ernst M. Bomhard & J. Fred Dice. (1999) Direct lysosomal uptake of α2-microglobulin contributes to chemically induced nephropathy. Kidney International 55:2, pages 529-545.
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Hyung Jong Jin. (1998) Isolation of human CYP4F2 genomic DNA and its 5′ end regulatory region structure. Archives of Pharmacal Research 21:1, pages 35-40.
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J. Ashby, A. Brady, C.R. Elcombe, B.M. Elliott, J. Ishmael, J. Odum, J.D. Tugwood, S. Kettle & I.F.H. Purchase. (2017) Mechanistically-based Human Hazard Assessment of Peroxisome Proliferator-induced Hepatocarcinogenesis. Human & Experimental Toxicology 13:2_suppl, pages S1-S117.
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P. Bentley, I. Calder, C. Elcombe, P. Grasso, D. Stringer & H.-J. Wiegand. (1993) Hepatic peroxisome proliferation in rodents and its significance for humans. Food and Chemical Toxicology 31:11, pages 857-907.
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G C HardI S RodgersK P BaetckeW L RichardsR E McGaughyL R Valcovic. (1993) Hazard evaluation of chemicals that cause accumulation of alpha 2u-globulin, hyaline droplet nephropathy, and tubule neoplasia in the kidneys of male rats.. Environmental Health Perspectives 99, pages 313-349.
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John P. Vanden Heuvel, John W. DavisIIII, Rebecca Sommers & Richard E. Peterson. (2006) Renal excretion of perfluorooctanoic acid in male rats: Inhibitory effect of testosterone. Journal of Biochemical Toxicology 7:1, pages 31-36.
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Myron A. Mehlman. (2016) Dangerous and Cancer-Causing Properties of Products and Chemicals in the Oil Refining and Petrochemical Industry: Part I Carcinogenicity of Motor Fuels: Gasoline. Toxicology and Industrial Health 7:5-6, pages 143-152.
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Harald Osmundsen, Jon Bremer & Jan I. Pedersen. (1991) Metabolic aspects of peroxisomal β-oxidation. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 1085:2, pages 141-158.
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K. Beier & H.D. Fahimi. (1991) Environmental pollution by common chemicals and peroxisome proliferation Efficient detection by cytochemistry and automatic image analysis. Progress in Histochemistry and Cytochemistry 23:1-4, pages 150-163.
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D. F. Houlihan, D. R. Livingstone & R. F. LeeDavid R. Livingstone. 1991. Advances in Comparative and Environmental Physiology. Advances in Comparative and Environmental Physiology 45 185 .

Myron A. Mehlman. (2005) Dangerous properties of petroleum‐refining products: Carcinogenicity of motor fuels (Gasoline). Teratogenesis, Carcinogenesis, and Mutagenesis 10:5, pages 399-408.
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Norbert P. Page & Myron Mehlman. (2016) Health Effects of Gasoline Refueling Vapors and Measured Exposures At Service Stations. Toxicology and Industrial Health 5:5, pages 869-890.
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E. A. Lock. 1987. Nephrotoxicity in the experimental and clinical situation. Nephrotoxicity in the experimental and clinical situation 429 461 .

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The induction of ω and β-oxidation of fatty acids and effect on α_2u globulin content in the liver and kidney of rats administered 2, 2, 4-trimethylpentane

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The induction of ω and β-oxidation of fatty acids and effect on α2u globulin content in the liver and kidney of rats administered 2, 2, 4-trimethylpentane

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The induction of ω and β-oxidation of fatty acids and effect on α_2u globulin content in the liver and kidney of rats administered 2, 2, 4-trimethylpentane