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Xenobiotica
the fate of foreign compounds in biological systems
Volume 17, 1987 - Issue 6
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Original Article

Disposition and metabolism of indeloxazine hydrochloride, a cerebral activator, in rats

H. Kamimura Drug Metabolism Department, Central Research Laboratories, Yamanouchi Pharmaceutical Co., Ltd, No. 1–8, Azusawa-1-chome, Itabashi-ku, Tokyo, 174, Japan
,
Y. Enjoji Drug Metabolism Department, Central Research Laboratories, Yamanouchi Pharmaceutical Co., Ltd, No. 1–8, Azusawa-1-chome, Itabashi-ku, Tokyo, 174, Japan
,
H. Sasaki Drug Metabolism Department, Central Research Laboratories, Yamanouchi Pharmaceutical Co., Ltd, No. 1–8, Azusawa-1-chome, Itabashi-ku, Tokyo, 174, Japan
,
R. Kawai Drug Metabolism Department, Central Research Laboratories, Yamanouchi Pharmaceutical Co., Ltd, No. 1–8, Azusawa-1-chome, Itabashi-ku, Tokyo, 174, Japan
,
H. Kaniwa Physico Analysis Centre, Central Research Laboratories, Yamanouchi Pharmaceutical Co., Ltd, No. 1–8, Azusawa-1-chome, Itabashi-ku, Tokyo, 174, Japan
,
K. Niigata Chemistry Department, Central Research Laboratories, Yamanouchi Pharmaceutical Co., Ltd, No. 1–8, Azusawa-1-chome, Itabashi-ku, Tokyo, 174, Japan
&
S. Kageyama Drug Metabolism Department, Central Research Laboratories, Yamanouchi Pharmaceutical Co., Ltd, No. 1–8, Azusawa-1-chome, Itabashi-ku, Tokyo, 174, Japan
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Pages 645-658 | Received 03 Jan 1986, Published online: 30 Sep 2009

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D. McKillop, M. Hutchison, E. A. Partridge, N. Bushby, C. M. F. Cooper, J. A. Clarkson-Jones, W. Herron & H. C. Swaisland. (2004) Metabolic disposition of gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, in rat, dog and man. Xenobiotica 34:10, pages 917-934.
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H. Kamimura, R. Kawai & H. Kudo. (1988) Metabolic fate of indeloxazine hydrochloride: α-glucoside formation in rats. Xenobiotica 18:2, pages 141-149.
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Angeliki P. Kourounakis, Dimitrios Xanthopoulos & Ariadni Tzara. (2020) Morpholine as a privileged structure: A review on the medicinal chemistry and pharmacological activity of morpholine containing bioactive molecules. Medicinal Research Reviews 40:2, pages 709-752.
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Michael Gerisch, Thomas Schwarz, Dieter Lang, Gabriele Rohde, Stefanie Reif, Isabelle Genvresse, Susanne Reschke, Dorina van der Mey & Camille Granvil. (2017) Pharmacokinetics of intravenous pan-class I phosphatidylinositol 3-kinase (PI3K) inhibitor [14C]copanlisib (BAY 80-6946) in a mass balance study in healthy male volunteers. Cancer Chemotherapy and Pharmacology 80:3, pages 535-544.
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Philippe Dostert, Margherita S. Benedetti & Italo Poggesi. (1997) Review of the pharmacokinetics and metabolism of reboxetine, a selective noradrenaline reuptake inhibitor. European Neuropsychopharmacology 7:1, pages S23-S35.
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I. A. Blair. 1994. Pharmacokinetics of Drugs. Pharmacokinetics of Drugs 41 84 .
G. Lin, K. K. Midha & E. M. Hawes. (2009) Synthesis of the piperidinone metabolites of piperidine type phenothiazine antipsychotic drugs via ruthenium tetroxide oxidation . Journal of Heterocyclic Chemistry 28:2, pages 215-219.
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