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Xenobiotica
the fate of foreign compounds in biological systems
Volume 17, 1987 - Issue 6
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Original Article

The metabolic sulphation of polyethyleneglycols by isolated perfused rat and guinea-pig livers

A. B. Roy Department of Biochemistry, University College, Cardiff, CF1 1XL, UK; Protein Chemistry Group, John Curtin School of Medical Research, Australian National University, GPO Box 334, Canberra, ACT, 2601, Australia
,
C. G. Curtis Department of Biochemistry, University College, Cardiff, CF1 1XL, UK
&
Gillian M. Powell Department of Biochemistry, University College, Cardiff, CF1 1XL, UK
Pages 725-732 | Received 10 May 1986, Published online: 30 Sep 2009

Citations (16)

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Read on this site (3)

A. B. Roy, C. G. Curtis & H. Hughes. (1991) The uptake of oestrone from the lumen of the isolated perfused rat gut. Xenobiotica 21:4, pages 491-498.
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A. B. Roy, C. G. Curtis & Gillian M. Powell. (1988) The Inhibition by Chlorate of the Sulphation of Polyethyleneglycol in the Isolated Perfused Guinea Pig Liver. Xenobiotica 18:9, pages 1049-1055.
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A. B. Roy, C. G. Curtis & Gillian M. Powell. (1987) The metabolism of oestrone and some other steroids in isolated perfused rat and guinea pig livers. Xenobiotica 17:11, pages 1299-1313.
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Articles from other publishers (13)

Lei Yin, Yiling Pang, Lin Shan & Jingkai Gu. (2022) The In Vivo Pharmacokinetics of Block Copolymers Containing Polyethylene Glycol Used in Nanocarrier Drug Delivery Systems. Drug Metabolism and Disposition 50:6, pages 827-836.
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Li Di, Amanda Balesano, Samantha Jordan & Sophia M. Shi. (2021) The Role of Alcohol Dehydrogenase in Drug Metabolism: Beyond Ethanol Oxidation. The AAPS Journal 23:1.
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Cathy Lester, Allison Reis, Michael Laufersweiler, Shengde Wu & Karen Blackburn. (2018) Structure activity relationship (SAR) toxicological assessments: The role of expert judgment. Regulatory Toxicology and Pharmacology 92, pages 390-406.
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Harivardhan Reddy Lakkireddy & Didier Bazile. (2016) Building the design, translation and development principles of polymeric nanomedicines using the case of clinically advanced poly(lactide(glycolide))–poly(ethylene glycol) nanotechnology as a model: An industrial viewpoint. Advanced Drug Delivery Reviews 107, pages 289-332.
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Fusako Kawai. 2012. Microbial Degradation of Xenobiotics. Microbial Degradation of Xenobiotics 411 438 .
. (2007) Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to an application on the use of polyethylene glycol (PEG) as a film coating agent for use in food supplement products. EFSA Journal 5:1, pages 414.
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Rob Webster, Eric Didier, Philip Harris, Ned Siegel, Jeanne Stadler, Lorraine Tilbury & Dennis Smith. (2007) PEGylated Proteins: Evaluation of Their Safety in the Absence of Definitive Metabolism Studies. Drug Metabolism and Disposition 35:1, pages 9-16.
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Fusako Kawai. 2005. Biopolymers Online. Biopolymers Online.
S.J. Hermansky, D.A. Neptun, K.A. Loughran & H.W. Leung. (1995) Effects of polyethylene glycol 400 (PEG 400) following 13 weeks of gavage treatment in fischer-344 rats. Food and Chemical Toxicology 33:2, pages 139-149.
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Styrbjörn Friman, Börje Egestad, Jan Sjövall & Joar Svanvik. (1993) Hepatic excretion and metabolism of polyethylene glycols and mannitol in the cat. Journal of Hepatology 17:1, pages 48-55.
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S. Friman, P. Leandersson, C. Tagesson & J. Svanvik. (1990) Biliary excretion of different sized polyethylene glycols in the cat. Journal of Hepatology 11:2, pages 215-220.
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G.M. Powell, H.M. Hughes & C.G. Curtis. (1989) ISOLATED PERFUSED LIVER TECHNOLOGY FOR STUDYING METABOLIC AND TOXICOLOGICAL PROBLEMS. Drug Metabolism and Drug Interactions 7:1.
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G.M. Powell, G.F. White, C.G. Curtis & FA. Rose. (1988) SULPHOCONJUGATION AND SULPHOHYDROLYSIS. Drug Metabolism and Drug Interactions 6:3-4.
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