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Xenobiotica
the fate of foreign compounds in biological systems
Volume 17, 1987 - Issue 10
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Original Article

Effects of biliary excretion on the disposition of felodipine and metabolites in the rat

T. A. Sutfin Department of Pharmacokinetics and Drug Metabolism, Hässle Cardiovascular Research Laboratories, S-431 83, Mölndal, Sweden
,
M. Gabrielsson Department of Pharmacokinetics and Drug Metabolism, Hässle Cardiovascular Research Laboratories, S-431 83, Mölndal, Sweden
&
C. G. Regårdh Department of Pharmacokinetics and Drug Metabolism, Hässle Cardiovascular Research Laboratories, S-431 83, Mölndal, Sweden
Pages 1203-1214 | Received 01 Nov 1986, Published online: 30 Sep 2009

Citations (6)

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Read on this site (1)

U. G. Eriksson, K. J. Hoffmann, R. Simonsson & C. G. Regårdh. (1991) Pharmacokinetics of the enantiomers of felodipine in the dog after oral and intravenous administration of a pseudoracemic mixture. Xenobiotica 21:1, pages 75-84.
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Articles from other publishers (5)

Ken Grime & Stuart W. Paine. (2013) Species Differences in Biliary Clearance and Possible Relevance of Hepatic Uptake and Efflux Transporters Involvement. Drug Metabolism and Disposition 41:2, pages 372-378.
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Yuan H Zhao, Michael H Abraham, Joelle Le, Anne Hersey, Chris N Luscombe, Gordon Beck, Brad Sherborne & Ian Cooper. (2003) Evaluation of rat intestinal absorption data and correlation with human intestinal absorption. European Journal of Medicinal Chemistry 38:3, pages 233-243.
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S. X. Wang, T. A. Sutfin & C. G. RegÅrdh. (1992) The effect of felodipine on bile flow in pentobarbital anaesthetized rats and conscious rats receiving bile salt supplementation. European Journal of Drug Metabolism and Pharmacokinetics 17:4, pages 263-268.
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Kimberly C. Yedinak & Larry M. Lopez. (2016) Felodipine: A New Dihydropyridine Calcium-Channel Antagonist. DICP 25:11, pages 1193-1206.
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T. A. Sutfin, T. Lind, M. Gabrielsson & C. G. Reg»rdh. (1990) Biliary secretion of felodipine metabolites in man after intravenous [14C]felodipine. European Journal of Clinical Pharmacology 38:5, pages 421-424.
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