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Xenobiotica
the fate of foreign compounds in biological systems
Volume 18, 1988 - Issue 2
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Original Article

The use of single sample clearance estimates to probe hepatic drug metabolism in rats. II

K. A. Bachmann Department of Pharmacology, College of Pharmacy, The University of Toledo, 2801W. Bancroft Street, Toledo, Ohio, 43606, USA
,
D. Jahn Department of Pharmacology, College of Pharmacy, The University of Toledo, 2801W. Bancroft Street, Toledo, Ohio, 43606, USA
,
C. Yang Department of Pharmacology, College of Pharmacy, The University of Toledo, 2801W. Bancroft Street, Toledo, Ohio, 43606, USA
&
J. Schwartz Department of Pharmacology, College of Pharmacy, The University of Toledo, 2801W. Bancroft Street, Toledo, Ohio, 43606, USA
Pages 161-167 | Received 03 Mar 1987, Published online: 30 Sep 2009

Citations (6)

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Read on this site (2)

K. A. Bachmann, M. S. Madhira & G. O. Rankin. (1992) The effects of cobalt chloride, SKF-525A, and N-(3,5-dichlorophenyl)succinimide on in vivo hepatic mixed function oxidase activity as determined by single-sample plasma clearances. Xenobiotica 22:1, pages 27-31.
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K. A. Bachmann. (1989) The use of single-sample clearance estimates to probe hepatic drug metabolism in rats. IV. A model for possible application to phenotyping xenobiotic influences on human drug metabolism. Xenobiotica 19:12, pages 1449-1459.
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Articles from other publishers (4)

Robert P Shrewsbury & Donald D Hong. (1990) The effect of Fluosol-DA and Hespan haemodilution on S -warfarin elimination in the rat . Journal of Pharmacy and Pharmacology 42:9, pages 665-666.
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Robert P Shrewsbury, Sharon R Oliver, Lee M Lewis, Wanda T Anderson & Lisa G White. (1989) The effect of varying extents of Fluosol-DA or normal saline haemodilution on the dose dependent kinetics of phenytoin in the rat. Journal of Pharmacy and Pharmacology 41:8, pages 582-584.
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Yoon Gyoon Kim, Min Kyung Cho, Jong Won Kwon, Sang Geon Kim, Suk Jae Chung, Chang-Koo Shim & Myung Gull Lee. (2001) Effects of cysteine on the pharmacokinetics of intravenous phenytoin in rats with protein–calorie malnutrition. International Journal of Pharmaceutics 229:1-2, pages 45-55.
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R. P. Shrewsbury & L. G. White. (1990) The effect of moderate hemodilution with Fluosol-DA or normal saline on acetaminophen disposition in the rat. Experientia 46:2, pages 213-217.
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