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Xenobiotica
the fate of foreign compounds in biological systems
Volume 18, 1988 - Issue 2
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Original Article

Identification and quantitation in human liver of cytochromes P-450 analogous to rabbit cytochromes P-450 forms 4 and 6

Michael E. McManus Department of Clinical Pharmacology, School of Medicine, Flinders University of South Australia, Bedford Park, 5042, Australia
,
Ieva Stupans Department of Clinical Pharmacology, School of Medicine, Flinders University of South Australia, Bedford Park, 5042, Australia
,
Berardo Ioannoni Department of Clinical Pharmacology, School of Medicine, Flinders University of South Australia, Bedford Park, 5042, Australia
,
Wendy Burgess Department of Clinical Pharmacology, School of Medicine, Flinders University of South Australia, Bedford Park, 5042, Australia
,
Richard A. Robson Department of Clinical Pharmacology, School of Medicine, Flinders University of South Australia, Bedford Park, 5042, Australia
&
Donald J. Birkett Department of Clinical Pharmacology, School of Medicine, Flinders University of South Australia, Bedford Park, 5042, Australia
Pages 207-216 | Received 20 Mar 1987, Published online: 30 Sep 2009

Citations (12)

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K. Lavrijsen, J. Van Houdt, D. Van Dyck, J. Hendrickx, M. Bockx, R. Hurkmans, W. Meuldermans, L. Le Jeune, W. Lauwers & J. Heykants. (1992) Comparative metabolism of flunarizine in rats, dogs and man: an in vitro study with subcellular liver fractions and isolated hepatocytes. Xenobiotica 22:7, pages 815-836.
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C. Ioannides & D. V. Parke. (1990) The Cytochrome P450 I Gene Family of Microsomal Hemoproteins and Their Role in the Metabolic Activation of Chemicals. Drug Metabolism Reviews 22:1, pages 1-85.
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Articles from other publishers (10)

Henrik E. Poulsen & Steffen Loft. 1994. Use of Mechanistic Information in Risk Assessment. Use of Mechanistic Information in Risk Assessment 211 222 .
Frank J. Gonzalez. (1993) Molecular biology of human xenobiotic-metabolizing cytochromes P450: role of vaccinia virus cDNA expression in evaluating catalytic function. Toxicology 82:1-3, pages 77-88.
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F. J. Gonzalez. 1993. Cytochrome P450. Cytochrome P450 239 257 .
F J GonzalezH V Gelboin. (1992) Human cytochromes P450: evolution and cDNA-directed expression.. Environmental Health Perspectives 98, pages 81-85.
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Frank J. Gonzalez. (1992) Human cytochromes P450: problems and prospects. Trends in Pharmacological Sciences 13, pages 346-352.
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Geoffrey D. Wheelock, Yasuhiko Konno & Jeffrey G. Scott. (2006) Expression of cytochrome P‐450 lpr Is developmentally regulated and limited to house fly . Journal of Biochemical Toxicology 6:4, pages 239-246.
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Geoffrey D. Wheelock & Jeffrey G. Scott. (1990) Immunological detection of cytochrome P450 from insecticide resistant and susceptible house flies (Musca domestica). Pesticide Biochemistry and Physiology 38:2, pages 130-139.
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Michael E. McManus. (2007) THE ROLE OF CYTOCHROMES P‐450 AND N ‐ACETYL TRANSFERASE IN THE CARCINOGENICITY OF AROMATIC AMINES AND AMIDES . Clinical and Experimental Pharmacology and Physiology 16:6, pages 491-495.
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M.J. Whiting, R.A. Wishart, M.R. Gowing, M.E. McManus & A.M. Mackinnon. (1989) Bile acid synthesis and secretion by rabbit hepatocytes in primary monolayer culture: comparison with rat hepatocytes. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 1001:2, pages 176-184.
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Yasushi Yamazoe, Medhat Abu‐Zeid, Kiyomi Yamauchi & Ryuichi Kato. (2005) Metabolic Activation of Pyrolysate Arylamines by Human Liver Microsomes; Possible Involvement of a P‐448‐H Type Cytochrome P‐450. Japanese Journal of Cancer Research 79:11, pages 1159-1167.
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