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Xenobiotica
the fate of foreign compounds in biological systems
Volume 18, 1988 - Issue 5
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Original Article

Participation of cytochrome P-450 isozymes in N-demethylation, N-hydroxylation and aromatic hydroxylation of methamphetamine

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Pages 475-484 | Received 11 Feb 1987, Accepted 02 Dec 1987, Published online: 30 Sep 2009

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Mohammad Reza Eskandari, Mokhtar Rahmati, Ali Reza Khajeamiri, Farzad Kobarfard, Maryam Noubarani & Himan Heidari. (2014) A new approach on methamphetamine-induced hepatotoxicity: involvement of mitochondrial dysfunction. Xenobiotica 44:1, pages 70-76.
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M. Dostalek, J. Jurica, J. Pistovcakova, M. Hanesova, J. Tomandl, I. Linhart & A. Sulcova. (2007) Effect of methamphetamine on cytochrome P450 activity. Xenobiotica 37:12, pages 1355-1366.
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F. Peter Guengerich. (1990) Enzymatic Oxidation of Xenobiotic Chemical. Critical Reviews in Biochemistry and Molecular Biology 25:2, pages 97-153.
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E. Macúchová, M. Ševčíková, I. Hrebíčková, K. Nohejlová & R. Šlamberová. (2016) How various drugs affect anxiety‐related behavior in male and female rats prenatally exposed to methamphetamine. International Journal of Developmental Neuroscience 51:1, pages 1-11.
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Kate McDonnell‐Dowling & John P. Kelly. (2015) Does route of methamphetamine exposure during pregnancy have an impact on neonatal development and behaviour in rat offspring?. International Journal of Developmental Neuroscience 49:1, pages 14-22.
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Kei Zaitsu, Akihiro Miki, Munehiro Katagi & Hitoshi Tsuchihashi. (2008) Long-term stability of various drugs and metabolites in urine, and preventive measures against their decomposition with special attention to filtration sterilization. Forensic Science International 174:2-3, pages 189-196.
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Yuji Ishii, Megumi Iwanaga, Yoshio Nishimura, Shuso Takeda, Shin-ichi Ikushiro, Kiyoshi Nagata, Yasushi Yamazoe, Peter I. Mackenzie & Hideyuki Yamada. (2007) Protein-Protein Interactions between Rat Hepatic Cytochromes P450 (P450s) and UDP-Glucuronosyltransferases (UGTs): Evidence for the Functionally Active UGT in P450-UGT Complex. Drug Metabolism and Pharmacokinetics 22:5, pages 367-376.
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W.F. Trager. 2007. Comprehensive Medicinal Chemistry II. Comprehensive Medicinal Chemistry II 87 132 .
Matthew A. Cerny & Robert P. Hanzlik. (2005) Cyclopropylamine inactivation of cytochromes P450: Role of metabolic intermediate complexes. Archives of Biochemistry and Biophysics 436:2, pages 265-275.
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Shuso Takeda, Yuji Ishii, Megumi Iwanaga, Peter I. Mackenzie, Kiyoshi Nagata, Yasushi Yamazoe, Kazuta Oguri & Hideyuki Yamada. (2005) Modulation of UDP-Glucuronosyltransferase Function by Cytochrome P450: Evidence for the Alteration of UGT2B7-Catalyzed Glucuronidation of Morphine by CYP3A4. Molecular Pharmacology 67:3, pages 665-672.
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Ken-ichiro Taura, Hideyuki Yamada, Eri Naito, Noritaka Ariyoshi, Masa-aki Mori & Kazuta Oguri. (2002) Activation of microsomal epoxide hydrolase by interaction with cytochromes P450: kinetic analysis of the association and substrate-specific activation of epoxide hydrolase function. Archives of Biochemistry and Biophysics 402:2, pages 275-280.
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Xiaolin Deng, Bruce Ladenheim, Li-I Tsao & Jean Lud Cadet. (1999) Null Mutation of c-fos Causes Exacerbation of Methamphetamine-Induced Neurotoxicity. The Journal of Neuroscience 19:22, pages 10107-10115.
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ARTHUR K. CHO, SHIZUO NARIMATSU & YOSHITO KUMAGAI. (1999) Metabolism of drugs of abuse by cytochromes P450. Addiction Biology 4:3, pages 283-301.
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Charles V. Vorhees, Tracy M. Reed, Mary A. Schilling, J.Edward Fisher, Mary S. Moran, Gregg D. Cappon & Daniel W. Nebert. (1998) Cyp2d1 Polymorphism in Methamphetamine-Treated Rats. Neurotoxicology and Teratology 20:3, pages 265-273.
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Ning-Yuan Li, Yan Li & Edward M. Sellers. (1997) An improved HPLC method for analysis of methamphetamine and its metabolites in plasma. European Journal of Drug Metabolism and Pharmacokinetics 22:4, pages 427-432.
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Barbara Ann Halkier. (1996) Catalytic reactivities and structure/function relationships of cytochrome P450 enzymes. Phytochemistry 43:1, pages 1-21.
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Peter Hlavica & Michael Lehnerer. (2006) Some aspects of the role of cytochrome P‐450 isozymes in the n‐oxidative transformation of secondary and tertiary amine compounds. Journal of Biochemical Toxicology 10:5, pages 275-285.
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Keith W. Elkins, James W. Gibb, Glen R. Hanson, Diana G. Wilkins & Michel Johnson. (1993) Effects of nimodipine on the amphetamine- and methamphetamine-induced decrease in tryptophan hydroxylase activity. European Journal of Pharmacology 250:3, pages 395-402.
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Peter Hlavica & Ute Künzel-Mulas. (1993) Metabolic N-oxide formation by rabbit-liver microsomal cytochrome P-4502B4: involvement of superoxide in the NADPH-dependent N-oxygenation of N,N-dimethylaniline. Biochimica et Biophysica Acta (BBA) - General Subjects 1158:1, pages 83-90.
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F. Peter Guengerich & Timothy L. Macdonald. 1993. Advances in Electron Transfer Chemistry. Advances in Electron Transfer Chemistry 191 241 .
F. P. Guengerich, A. Bondon, R. G. Böcker & T. L. Macdonald. 1991. N-Oxidation of Drugs. N-Oxidation of Drugs 141 155 .
F. Peter Guengerich, Tsutomu Shimada, Arnaud Bondon & Timothy L. Macdonald. 1991. Biological Reactive Intermediates IV. Biological Reactive Intermediates IV 1 11 .
Janeric Seidegård, Lena Grönquist & Per Olov Gunnarsson. (1990) Metabolism of a novel nitrosourea, tauromustine, in the rat. Biochemical Pharmacology 39:9, pages 1431-1436.
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F. Peter Guengerich. 1990. Biological Oxidation Systems. Biological Oxidation Systems 51 67 .
Hideyuki Yamada, Shinichiro Honda, Kazuta Oguri & Hidetoshi Yoshimura. (1989) A rabbit liver constitutive form of cytochrome P450 responsible for amphetamine deamination. Archives of Biochemistry and Biophysics 273:1, pages 26-33.
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A Bondon, T L Macdonald, T M Harris & F P Guengerich. (1989) Oxidation of Cycloalkylamines by Cytochrome P-450. Journal of Biological Chemistry 264:4, pages 1988-1997.
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B. Clement. (1989) STRUCTURAL REQUIREMENTS OF MICROSOMAL N-OXYGENATIONS DERIVED FROM STUDIES ON AMIDINES. Drug Metabolism and Drug Interactions 7:1.
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