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Xenobiotica
the fate of foreign compounds in biological systems
Volume 18, 1988 - Issue 5
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Original Article

Pharmacokinetics of rolipram in the rhesus and cynomolgus monkeys, the rat and the rabbit. Studies on species differences

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Pages 561-571 | Received 14 Jul 1987, Accepted 01 Jan 1988, Published online: 30 Sep 2009

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Leila Gobejishvili, Walter E Rodriguez, Philip Bauer, Yali Wang, Chirag Soni, Todd Lydic, Shirish Barve, Craig McClain & Claudio Maldonado. (2022) Novel Liposomal Rolipram Formulation for Clinical Application to Reduce Emesis. Drug Design, Development and Therapy 16, pages 1301-1309.
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Takatoshi Hikida, Nao J Gamo & Akira Sawa. (2012) DISC1 as a therapeutic target for mental illnesses. Expert Opinion on Therapeutic Targets 16:12, pages 1151-1160.
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Kouya Yamaki, Xiaojuan Li, Md. Aslam Hossain, A. H. M. Khurshid Alam, Shinji Taneda, Rie Yanagisawa, Hirohisa Takano & Shin Yoshino. (2007) Difference in Preventive Effects Between the Phosphodiesterase IV Inhibitor Rolipram and Anti-Arthritic Drugs on Antigen-Induced Arthritis in Mice. Immunological Investigations 36:2, pages 131-145.
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W. Krause, G. Kühne & H. Matthes. (1989) Pharmacokinetics of the Antidepressant Rolipram in Healthy Volunteers. Xenobiotica 19:6, pages 683-692.
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Artur Świerczek, Bartosz Pomierny, Elżbieta Wyska & William J. Jusko. (2022) Pharmacokinetic/Pharmacodynamic Assessment of Selective Phosphodiesterase Inhibitors in a Mouse Model of Autoimmune Hepatitis. Journal of Pharmacology and Experimental Therapeutics 381:2, pages 151-163.
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Mayasah Y. Al-Nema & Anand Gaurav. (2020) Phosphodiesterase as a Target for Cognition Enhancement in Schizophrenia. Current Topics in Medicinal Chemistry 20:26, pages 2404-2421.
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Yinuo Wu, Zhe Li, Yi-You Huang, Deyan Wu & Hai-Bin Luo. (2018) Novel Phosphodiesterase Inhibitors for Cognitive Improvement in Alzheimer’s Disease. Journal of Medicinal Chemistry 61:13, pages 5467-5483.
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P.R.A. Heckman, A. Blokland, E.P.P. Bollen & J. Prickaerts. (2018) Phosphodiesterase inhibition and modulation of corticostriatal and hippocampal circuits: Clinical overview and translational considerations. Neuroscience & Biobehavioral Reviews 87, pages 233-254.
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Yucong Peng, Jianxiang Jin, Linfeng Fan, Hangzhe Xu, Pingyou He, Jianru Li, Ting Chen, Wu Ruan & Gao Chen. (2018) Rolipram Attenuates Early Brain Injury Following Experimental Subarachnoid Hemorrhage in Rats: Possibly via Regulating the SIRT1/NF-κB Pathway. Neurochemical Research 43:4, pages 785-795.
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Qun Li, Yucong Peng, Linfeng Fan, Hangzhe Xu, Pingyou He, Shenglong Cao, Jianru Li, Ting Chen, Wu Ruan & Gao Chen. (2018) Phosphodiesterase-4 inhibition confers a neuroprotective efficacy against early brain injury following experimental subarachnoid hemorrhage in rats by attenuating neuronal apoptosis through the SIRT1/Akt pathway. Biomedicine & Pharmacotherapy 99, pages 947-955.
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P. R. A. Heckman, J. V. Schweimer, T. Sharp, J. Prickaerts & A. Blokland. (2017) Phosphodiesterase 4 inhibition affects both the direct and indirect pathway: an electrophysiological study examining the tri-phasic response in the substantia nigra pars reticulata. Brain Structure and Function 223:2, pages 739-748.
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Clark R. Sims, Sharda P. Singh, Shengyu Mu, Neriman Gokden, Dala Zakaria, Trung C. Nguyen & Philip R. Mayeux. (2017) Rolipram Improves Outcome in a Rat Model of Infant Sepsis-Induced Cardiorenal Syndrome. Frontiers in Pharmacology 8.
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Roberta Ricciarelli, Chiara Brullo, Jos Prickaerts, Ottavio Arancio, Carla Villa, Claudia Rebosio, Elisa Calcagno, Matilde Balbi, Britt T. J. van Hagen, Elentina K. Argyrousi, Hong Zhang, Maria Adelaide Pronzato, Olga Bruno & Ernesto Fedele. (2017) Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer’s disease. Scientific Reports 7:1.
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Ya Miao, Ting He, Yitong Zhu, Wei Li, Beiyuan Wang & Yuan Zhong. (2015) Activation of Hippocampal CREB by Rolipram Partially Recovers Balance Between TNF-α and IL-10 Levels and Improves Cognitive Deficits in Diabetic Rats. Cellular and Molecular Neurobiology 35:8, pages 1157-1164.
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Chia-Lang Fang, Chih-Jen Wen, Ibrahim A. Aljuffali, Calvin T. Sung, Chun-Lin Huang & Jia-You Fang. (2015) Passive targeting of phosphatiosomes increases rolipram delivery to the lungs for treatment of acute lung injury: An animal study. Journal of Controlled Release 213, pages 69-78.
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Ajaib S. Paintlia, Manjeet K. Paintlia, Inderjit Singh, Robert B. Skoff & Avtar K. Singh. (2008) Combination therapy of lovastatin and rolipram provides neuroprotection and promotes neurorepair in inflammatory demyelination model of multiple sclerosis. Glia 57:2, pages 182-193.
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