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H.-G. Koebe, S. Pahernik, P. Eyer & F.-W. Schildberg. (1994) Collagen gel immobilization: A useful cell culture technique for long-term metabolic studies on human hepatocytes. Xenobiotica 24:2, pages 95-107.
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Articles from other publishers (30)
. 2010. Drug Safety Evaluation. Drug Safety Evaluation
788
860
.
Shayne Cox Gad. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia.
María José Gómez-Lechón, José V. Castell & María Teresa Donato. 2010. Hepatocytes. Hepatocytes
389
415
.
Saura C. Sahu, Dennis I. Ruggles & Michael W. O’Donnell. (2006) Prooxidant activity and toxicity of nordihydroguaiaretic acid in clone-9 rat hepatocyte cultures. Food and Chemical Toxicology 44:10, pages 1751-1757.
Crossref
Crossref
Johanna M. Beekman, Franziska Boess, Heinrich Hildebrand, Arno Kalkuhl & Laura Suter. (2006) Gene Expression Analysis of the Hepatotoxicant Methapyrilene in Primary Rat Hepatocytes: An Interlaboratory Study. Environmental Health Perspectives 114:1, pages 92-99.
Crossref
Crossref
Greetje Elaut, Tamara Vanhaecke, Yvan Vander Heyden & Vera Rogiers. (2005) Spontaneous apoptosis, necrosis, energy status, glutathione levels and biotransformation capacities of isolated rat hepatocytes in suspension: Effect of the incubation medium. Biochemical Pharmacology 69:12, pages 1829-1838.
Crossref
Crossref
Erik Eschbach, Shyam S. Chatterjee, Michael Nöldner, Eric Gottwald, Hermann Dertinger, Karl-Friedrich Weibezahn & Gudrun Knedlitschek. (2005) Microstructured scaffolds for liver tissue cultures of high cell density: Morphological and biochemical characterization of tissue aggregates. Journal of Cellular Biochemistry 95:2, pages 243-255.
Crossref
Crossref
Albert Li. 2001. Handbook of Drug Screening. Handbook of Drug Screening.
Albert P. Li. 2000. The Hepatocyte Review. The Hepatocyte Review
391
410
.
Michael Sinz. 1999. Handbook of Drug Metabolism. Handbook of Drug Metabolism
401
424
.
JOSÉ V. CASTELL, MARÍA JOSÉ GÓMEZ-LECHÓN, XAVIER PONSODA & ROQUE BORT. 1997. In Vitro Methods in Pharmaceutical Research. In Vitro Methods in Pharmaceutical Research
375
410
.
ALISON E.M. VICKERS. 1997. In Vitro Methods in Pharmaceutical Research. In Vitro Methods in Pharmaceutical Research
103
127
.
Francisco Boscá, Germano Carganico, JoséV. Castell, Maria J. Gómez-Lechón, Daniel Hernandez, David Mauleón, Luis A. Martínez & Miguel A. Miranda. (1995) Evaluation of ketoprofen (R, S and ) phototoxicity by a battery of in vitro assays. Journal of Photochemistry and Photobiology B: Biology 31:3, pages 133-138.
Crossref
Crossref
Martin D. Barratt, Jose V. Castell, Mark Chamberlain, Robert D. Combes, John C. Dearden, Julia H. Fentem, Ingrid Gerner, Alessandro Giuliani, Tim J.B. Gray, David J. Livingstone, W. McLean Provan, Fons A.J.J.L. Rutten, Henk J.M. Verhaar & Peter Zbinden. (2020) The Integrated Use of Alternative Approaches for Predicting Toxic Hazard. Alternatives to Laboratory Animals 23:3, pages 410-429.
Crossref
Crossref
Jose V. Castell, Maria J. Gomez‐Lechon, Daniel Hernandez, Luis A. Martinez & Miguel A. Miranda. (2008) MOLECULAR BASIS OF DRUG PHOTOTOXICITY: PHOTOSENSITIZED CELL DAMAGE BY THE MAJOR PHOTOPRODUCT OF TIAPROFENIC ACID. Photochemistry and Photobiology 60:6, pages 586-590.
Crossref
Crossref
Bas J. Blaauboer, Alan R. Boobis, Jose V. Castell, Sandra Coecke, Geny M.M. Groothuis, Andre Guillouzo, Tony J. Hall, Gabrielle M. Hawksworth, Giocondo Lorenzon, Herbert G. Miltenburger, Vera Rogiers, Paul Skett, Pia Villa & Friedrich J. Wiebel. (2020) The Practical Applicability of Hepatocyte Cultures in Routine Testing. Alternatives to Laboratory Animals 22:4, pages 231-241.
Crossref
Crossref
M.C. Calleja, G. Persoone & P. Geladi. (1994) Human acute toxicity prediction of the first 50 MEIC chemicals by a battery of ecotoxicological tests and physicochemical properties. Food and Chemical Toxicology 32:2, pages 173-187.
Crossref
Crossref
Jose V. Castell, Maria J. Gomez‐Lechon, Carmina Grassa, Luis A. Martinez, Miguel A. Miranda & Pilar Tarrega. (2008) PHOTODYNAMIC LIPID PEROXIDATION BY THE PHOTOSENSITIZING NONSTEROIDAL ANTIINFLAMMATORY DRUGS SUPROFEN AND TIAPROFENIC ACID. Photochemistry and Photobiology 59:1, pages 35-39.
Crossref
Crossref
Mabel C. Calleja, Guido Persoone & Paul Geladi. (2020) The Predictive Potential of a Battery of Ecotoxicological Tests for Human Acute Toxicity, as Evaluated with the First 50 MEIC Chemicals. Alternatives to Laboratory Animals 21:3, pages 330-349.
Crossref
Crossref
May Akrawi, Vera Rogiers, Yves Vandenberghe, Colin N.A. Palmer, Antoine Vercruysse, Elizabeth A. Shephard & Ian R. Phillips. (1993) Maintenance and induction in co-cultured rat hepatocytes of components of the cytochrome P450-mediated mono-oxygenase. Biochemical Pharmacology 45:8, pages 1583-1591.
Crossref
Crossref
Jose V. Castell, Maria J. Gomez‐Lechon, Carmina Grassa, Luis A. Martinez, Miguel A. Miranda & Pilar Tarrega. (2008) INVOLVEMENT OF DRUG‐DERIVED PEROXIDES IN THE PHOTOTOXICITY OF NAPROXEN and TIAPROFENIC ACID. Photochemistry and Photobiology 57:3, pages 486-490.
Crossref
Crossref
Julio C. Davila & Daniel Acosta. 1993. In Vitro Biological Systems. In Vitro Biological Systems
244
254
.
M.T. Donato, F. Goethals, M.J. Gómez-Lechón, D. Deboyser, I. De Coster, M. Roberfroid & J.V. Castell. (1992) Toxicity of the antitumoral drug datelliptium in hepatic cells: Use of models in vitro for the prediction of toxicity in vivo. Toxicology in Vitro 6:4, pages 295-302.
Crossref
Crossref
R. Jover, X. Ponsoda, J.V. Castell & M.J. Gómez-Lechón. (1992) Evaluation of the cytotoxicity of ten chemicals on human cultured hepatocytes: Predictability of human toxicity and comparison with rodent cell culture systems. Toxicology in Vitro 6:1, pages 47-52.
Crossref
Crossref
Ramiro Jover, Xavier Ponsoda, M.José Gómez-Lechón, Conrado Herrero, Javier Del Pino & JoséV. Castell. (1991) Potentiation of cocaine hepatotoxicity by ethanol in human hepatocytes. Toxicology and Applied Pharmacology 107:3, pages 526-534.
Crossref
Crossref
Sattar K. Abdul-Hussain & Harihara M. Mehendale. (1991) Studies on the age-dependent effects of galactosamine in primary rat hepatocyte cultures. Toxicology and Applied Pharmacology 107:3, pages 504-513.
Crossref
Crossref
Marie N. Blaude, Fabienne M. Goethals, Michel A. Ansay & Marcel B. Roberfroid. (1990) Interaction between aflatoxin B1 and oxytetracycline in isolated rat hepatocytes. Cell Biology and Toxicology 6:4, pages 339-351.
Crossref
Crossref
Ramiro Jover, Xavier Ponsoda, Jose Vicente Castell & Maria José Gómez-Lechón. (2020) Hepatotoxicity of Opiates and Cocaine on Different Hepatic Cellular Systems. Alternatives to Laboratory Animals 17:3, pages 240-245.
Crossref
Crossref
Xavier Ponsoda, Ramiro Jover, José Vicente Castell & Mariá José Gómez-Lechón. (2020)
In Vitro
Toxicity to Two Cellular Systems of the First Ten Chemicals on the MEIC List
. Alternatives to Laboratory Animals 17:3, pages 218-223.
Crossref
Crossref
J. Masanet, M.J. Gómez-Lechón & J.V. Castell. (1988) Hepatic toxicity of paraquat in primary cultures of rat hepatocytes. Toxicology in Vitro 2:4, pages 275-282.
Crossref
Crossref