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Xenobiotica
the fate of foreign compounds in biological systems
Volume 18, 1988 - Issue 7
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Original Article

Metabolism of hexachloro-1,3-butadiene in mice: in vivo and in vitro evidence for activation by glutathione conjugation

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Pages 803-816 | Received 27 Jul 1987, Accepted 08 Jan 1988, Published online: 30 Sep 2009

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Wolfgang Dekant & Spiros Vamvakas. (1996) Biotransformation and Membrane Transport in Nephrotoxicity. Critical Reviews in Toxicology 26:3, pages 309-334.
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W. Dekant & S. Vamvakas. (1993) Glutathione-dependent bioactivation of xenobiotics. Xenobiotica 23:8, pages 873-887.
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Articles from other publishers (22)

Mónica G. Silva, Daniela Mendes, M. Manuel Oliveira, Paula B. Andrade, Romeu A. Videira & Francisco Peixoto. 2023. Mitochondrial Intoxication. Mitochondrial Intoxication 493 526 .
L.H. Lash. 2018. Comprehensive Toxicology. Comprehensive Toxicology 380 409 .
A. Hartwig. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1008 1052 .
A. J. L. Cooper & J. T. Pinto. (2006) Cysteine S-conjugate β-lyases. Amino Acids 30:1, pages 1-15.
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Wolfgang Dekant. (2001) Chemical-induced nephrotoxicity mediated by glutathione S-conjugate formation. Toxicology Letters 124:1-3, pages 21-36.
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. 2001. Metabolic Maps. Metabolic Maps 288 295 .
G. Morel, M. Ban, D. Hettich & N. Huguet. (1999) Role of SAM-dependent thiol methylation in the renal toxicity of several solvents in mice. Journal of Applied Toxicology 19:1, pages 47-54.
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Wolfgang Dekant, Gerhard Birner, Michael Werner & Jean Parker. (1998) Glutathione conjugation of perchloroethene in subcellular fractions from rodent and human liver and kidney. Chemico-Biological Interactions 116:1-2, pages 31-43.
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M. W. Anders & W. Dekant. (1998) GLUTATHIONE-DEPENDENT BIOACTIVATION OF HALOALKENES. Annual Review of Pharmacology and Toxicology 38:1, pages 501-537.
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W. Dekant. 1997. Risk and Progression Factors in Carcinogenesis. Risk and Progression Factors in Carcinogenesis 77 87 .
W. Dekant. 1996. Toxicology - From Cells to Man. Toxicology - From Cells to Man 163 172 .
Wolfgang Dekant. 1996. Biological Reactive Intermediates V. Biological Reactive Intermediates V 297 312 .
M.W. Anders & Wolfgang Dekant. 1994. 431 448 .
Wolfgang Dekant, Spyridon Vamvakas & M.W. Andersl. 1994. 115 162 .
George J. Kaloyanides. (1991) Metabolic interactions between drugs and renal tubulo-interstitial cells: Role in nephrotoxicity. Kidney International 39:3, pages 531-540.
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Michael Koob & Wolfgang Dekant. (1991) Bioactivation of xenobiotics by formation of toxic glutathione conjugates. Chemico-Biological Interactions 77:2, pages 107-136.
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W DekantS VamvakasM KoobA KöchlingW KanhaiD MüllerD Henschler. (1990) A mechanism of haloalkene-induced renal carcinogenesis.. Environmental Health Perspectives 88, pages 107-110.
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J. de Ceaurriz & M. Ban. (1990) Role of γ-glutamyltranspeptidase and β-lyase in the nephrotoxicity of hexachloro-1,3-butadiene and methyl mercury in mice. Toxicology Letters 50:2-3, pages 249-256.
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Lawrence H. Lash, Adnan A. Elfarra, Donna Rakiewicz-Nemeth & M.W. Anders. (1990) Bioactivation mechanism of cytotoxic homocysteine S-conjugates. Archives of Biochemistry and Biophysics 276:2, pages 322-330.
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W. Dekant, S. Vamvakas & M.W. Anders. (1990) Bioactivation of hexachlorobutadiene by glutathione conjugation. Food and Chemical Toxicology 28:4, pages 285-293.
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Wolfgang Dekant, Michael Koob & Dietrich Henschler. (1990) Metabolism of trichloroethene — in vivo and in vitro evidence for activation by glutathione conjugation. Chemico-Biological Interactions 73:1, pages 89-101.
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Wolfgang Dekant, Klemens Berthold, Spyridon Vamvakas & Dietrich Henschler. (1988) Thioacylating agents as ultimate intermediates in the β-lyase catalysed metabolism of S-(pentachlorobutadienyl)-L-cysteine. Chemico-Biological Interactions 67:1-2, pages 139-148.
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