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Xenobiotica
the fate of foreign compounds in biological systems
Volume 18, 1988 - Issue 9
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Original Article

In vitro Inhibition by Stiripentol of Rat Brain Cytochrome P-450-Mediated Naphthalene Hydroxylation

Marcel Mesnil School of Pharmacy, University of Lausanne, Place du Chaˇteau, CH-1005, Lausanne, Switzerland
,
Bernard Testa School of Pharmacy, University of Lausanne, Place du Chaˇteau, CH-1005, Lausanne, Switzerland
&
Peter Jenner University Department of Neurology, Institute of Psychiatry and King' College Hospital Medical School, Denmark Hill, London, SE5 8AF, UK
Pages 1097-1106 | Received 20 Dec 1987, Accepted 01 May 1988, Published online: 30 Sep 2009

Citations (15)

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Stanislaw J Czuczwar, Michal K Trojnar, Aleksandra Gergont, Slawomir Kroczka & Marek Kacinski. (2008) Stiripentol – characteristic of a new antiepileptic drug. Expert Opinion on Drug Discovery 3:4, pages 453-460.
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Bernard Testa. (1990) Mechanisms of inhibition of xenobiotic-metabolizing enzymes. Xenobiotica 20:11, pages 1129-1137.
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Articles from other publishers (13)

Nikhil Taxak, Bhargav Patel & Prasad V. Bharatam. (2013) Carbene Generation by Cytochromes and Electronic Structure of Heme-Iron-Porphyrin-Carbene Complex: A Quantum Chemical Study. Inorganic Chemistry 52:9, pages 5097-5109.
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Richard H Finnell, Gregory D Bennett, Gary G Mather, Bogdan Wlodarczyk, Manoj Bajpai & René H Levy. (1999) Effect of stiripentol dose on phenytoin-induced teratogenesis in a mouse model. Reproductive Toxicology 13:2, pages 85-91.
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Julia A Hasler, Ronald Estabrook, Michael Murray, Irina Pikuleva, Michael Waterman, Jorge Capdevila, Vijakumar Holla, Christian Helvig, John R Falck, Geoffrey Farrell, Laurence S Kaminsky, Simon D Spivack, Eric Boitier & Philippe Beaune. (1999) Human cytochromes P450. Molecular Aspects of Medicine 20:1-2, pages 1-137.
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Michael Murray. (2007) DRUG‐MEDIATED INACTIVATION OF CYTOCHROME P450. Clinical and Experimental Pharmacology and Physiology 24:7, pages 465-470.
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Nona K. Phillips & Joan S. Lockard. (2005) Infant Monkey Hyperexcitability After Prenatal Exposure to Antiepileptic Compounds. Epilepsia 37:10, pages 991-999.
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Richard H. Finnell, Gregory D. Bennett, John T. Slattery, Benny M. Amore, Manoj Bajpai & René H. Levy. (2005) Effect of treatment with phenobarbital and stiripentol on carbamazepine‐induced teratogenicity and reactive metabolite formation. Teratology 52:6, pages 324-332.
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Margaret Warner, Adrian Wyss, Shigetaka Yoshida & Jan-Åke Gustafsson. 1994. Neurobiology of Steroids. Neurobiology of Steroids 51 66 .
Nona K. Phillips & Joan S. Lockard. (1993) Phenytoin and/or Stiripentol in Pregnancy: Infant Monkey Hyperexcitability. Epilepsia 34:6, pages 1117-1122.
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Jacqueline R. Farwell, Gail D. Anderson, Bradley M. Kerr, Jacques A. Tor & René H. Levy. (2005) Stiripentol in Atypical Absence Seizures in Children: An Open Trial. Epilepsia 34:2, pages 305-311.
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T. Hansson, C. von Bahr, M. Marklund, J.‐O. Svensson, M. Ingelman‐Sundberg & J. Lundström. (2009) Different Regiospecificity in the Hydroxylation of the Antidepressant Desmethylimipramine Between Rat Brain and Liver. Pharmacology & Toxicology 71:6, pages 416-419.
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Bradley M. Kerr, Juan M. Martinez‐Lage, C. Viteri, Jacques Tor, A. Craig Eddy & René H. Levy. (2007) Carbamazepine Dose Requirements During Stiripentol Therapy: Influence of Cytochrome P‐450 Inhibition Stiripentol. Epilepsia 32:2, pages 267-274.
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Alain Minn, Jean-François Ghersi-Egea, Rachel Perrin, Brigitte Leininger & Gérard Siest. (1991) Drug metabolizing enzymes in the brain and cerebral microvessels. Brain Research Reviews 16:1, pages 65-82.
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K. Zahlsen, A. M. Nilsen, I. Eide & O. G. Nilsen. (1990) Accumulation and Distribution of Aliphatic (n-Nonane), Aromatic (1,2,4-Trimethylbenzene) and Naphthenic (1,2,4-Trimethylcyclohexane) Hydrocarbons in the Rat after Repeated Inhalation. Pharmacology & Toxicology 67:5, pages 436-440.
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