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Xenobiotica
the fate of foreign compounds in biological systems
Volume 18, 1988 - Issue 12
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Original Article

Species Variation and Stereoselectivity in the Metabolism of Nicotine Enantiomers

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Pages 1361-1372 | Received 17 Dec 1987, Accepted 10 Jun 1988, Published online: 30 Sep 2009

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Read on this site (3)

Gabriel A. Kyerematen & Elliot S. Vesell. (1991) Metabolism of Nicotine. Drug Metabolism Reviews 23:1-2, pages 3-41.
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P. Voncken, K. Rustemeier & G. Schepers. (1990) Identification of cis-3'-hydroxycotinine as a urinary nicotine metabolite. Xenobiotica 20:12, pages 1353-1356.
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Articles from other publishers (32)

Neal A Shah, Zhuoran Li, Tiana McMann, Alec J Calac, Nicolette Le, Matthew C Nali, Raphael E Cuomo & Tim K Mackey. (2023) Identification and Characterization of Synthetic Nicotine Product Promotion and Sales on Instagram Using Natural Language Processing. Nicotine and Tobacco Research.
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Sven-Eric Jordt. (2023) Synthetic nicotine has arrived. Tobacco Control 32:e1, pages e113-e117.
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Javier Íbias & Arbi Nazarian. (2020) Sex differences in nicotine-induced impulsivity and its reversal with bupropion in rats. Journal of Psychopharmacology 34:12, pages 1382-1392.
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M. J. Moerke, L. R. McMahon & J. L. Wilkerson. (2020) More than Smoke and Patches: The Quest for Pharmacotherapies to Treat Tobacco Use Disorder. Pharmacological Reviews 72:2, pages 527-557.
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Sharon Miksys, Susanne L.T. Cappendijk, William M. Perry, Bin Zhao & Rachel F. Tyndale. (2013) Nicotine Kinetics in Zebra Finches In Vivo and In Vitro. Drug Metabolism and Disposition 41:6, pages 1240-1246.
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Dariusz Pogocki, Tomasz Ruman, Magdalena Danilczuk, Marek Danilczuk, Monika Celuch & Elżbieta Wałajtys-Rode. (2007) Application of nicotine enantiomers, derivatives and analogues in therapy of neurodegenerative disorders. European Journal of Pharmacology 563:1-3, pages 18-39.
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Janne Hukkanen, Pleyton JacobIIIIII & Neal L. Benowitz. (2005) Metabolism and Disposition Kinetics of Nicotine. Pharmacological Reviews 57:1, pages 79-115.
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Deniz Yildiz. (2004) Nicotine, its metabolism and an overview of its biological effects. Toxicon 43:6, pages 619-632.
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Cristinel Sandu, Calin B. Chiribau & Roderich Brandsch. (2003) Characterization of HdnoR, the Transcriptional Repressor of the 6-Hydroxy-D-nicotine Oxidase Gene of Arthrobacter nicotinovorans pAO1, and its DNA-binding Activity in Response to L- and D-Nicotine Derivatives. Journal of Biological Chemistry 278:51, pages 51307-51315.
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T. Robinson. 2000. Bioactive Natural Products (Part C). Bioactive Natural Products (Part C) 3 54 .
Kenneth Perkins, Eric Donny & Anthony Caggiula. (1999) Sex differences in nicotine effects and self-administration: Review of human and animal evidence. Nicotine & Tobacco Research 1:4, pages 301-315.
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Klaus Rustemeier & Jean-Jacques Piadé. 1999. Analytical Determination of Nicotine and Related Compounds and their Metabolites. Analytical Determination of Nicotine and Related Compounds and their Metabolites 489 529 .
Peter A. Crooks & Gary D. Byrd. 1999. Analytical Determination of Nicotine and Related Compounds and their Metabolites. Analytical Determination of Nicotine and Related Compounds and their Metabolites 225 264 .
John W. Gorrod & Georg Schepers. 1999. Analytical Determination of Nicotine and Related Compounds and their Metabolites. Analytical Determination of Nicotine and Related Compounds and their Metabolites 45 67 .
Deniz Yildiz, Nuran Ercal & Daniel W. Armstrong. (1998) Nicotine enantiomers and oxidative stress. Toxicology 130:2-3, pages 155-165.
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Daniel W. Armstrong, Xiande Wang & Nuran Ercal. (1998) Enantiomeric composition of nicotine in smokeless tobacco, medicinal products, and commercial reagents. Chirality 10:7, pages 587-591.
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Yubing Tang, Walter L. Zielinski & Heather M. Bigott. (1998) Separation of nicotine and nornicotine enantiomers via normal phase HPLC on derivatized cellulose chiral stationary phases. Chirality 10:4, pages 364-369.
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Y. Kuroiwa & T. Yoshida. 1997. Analytical Toxicology for Clinical, Forensic and Pharmaceutical Chemists. Analytical Toxicology for Clinical, Forensic and Pharmaceutical Chemists 621 662 .
Peter A. Crooks & Linda P. Dwoskin. (1997) Contribution of CNS nicotine metabolites to the neuropharmacological effects of nicotine and tobacco smoking. Biochemical Pharmacology 54:7, pages 743-753.
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C. Giachetti, A. Assandri, G. Mautone, E. Tajana, B. Palumbo & R. Palumbo. (1996) Pharmacokinetics and metabolism of N-(2-hydroxyethyl)-2,5-[14C]-pyrrolidine (HEP, Epolamine) in male healthy volunteers. European Journal of Drug Metabolism and Pharmacokinetics 21:3, pages 261-268.
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G. Schepers, K. Rustemeier, R. -A. Walk & U. Hackenberg. (1993) Metabolism of S-nicotine in noninduced and aroclor-induced rats. European Journal of Drug Metabolism and Pharmacokinetics 18:2, pages 187-197.
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M.J. Seaton & E.S. Vesell. (1993) Variables affecting nicotine metabolism. Pharmacology & Therapeutics 60:3, pages 461-500.
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J. Gabrielsson & M. Gumbleton. 1993. Nicotine and Related Alkaloids. Nicotine and Related Alkaloids 181 195 .
M. Curvall & E. Kazemi Vala. 1993. Nicotine and Related Alkaloids. Nicotine and Related Alkaloids 147 179 .
P. A. Crooks. 1993. Nicotine and Related Alkaloids. Nicotine and Related Alkaloids 81 109 .
G. B. Neurath. 1993. Nicotine and Related Alkaloids. Nicotine and Related Alkaloids 61 80 .
S. Cholerton, N. W. McCracken & J. R. Idle. 1993. Nicotine and Related Alkaloids. Nicotine and Related Alkaloids 219 254 .
Demetrios Demetriou, Klaus Rustemeier, Peter Voncken & Georg Schepers. (2004) HPLC separation of the enantiomers of nicotine and nicotine‐like compounds. Chirality 5:5, pages 300-302.
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N. CastagnoliJr.Jr., M. Shigenaga, T. Carlson, W. F. Trager & A. Trevor. 1991. Effects of Nicotine on Biological Systems. Effects of Nicotine on Biological Systems 25 34 .
Gabriel A. Kyerematen, Monica Morgan, Genevieve Warner, Louis F. Martin & Elliot S. Vesell. (1990) Metabolism of nicotine by hepatocytes. Biochemical Pharmacology 40:8, pages 1747-1756.
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M.A. Chauncey & Shin-ichi Ninomiya. (1990) Metabolic studies with model cytochrome p-450 systems. Tetrahedron Letters 31:41, pages 5901-5904.
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Abdulghani A. Houdi, C.Steven Godin & Peter A. Crooks. (1988) Effect of continuous administration of nicotine on urinary histamine and Nτ-methylhistamme levels in the guinea pig. Toxicology Letters 44:1-2, pages 161-166.
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