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Xenobiotica
the fate of foreign compounds in biological systems
Volume 18, 1988 - Issue 1
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Research Article

Differences in adipose tissue distribution of basic lipophilic drugs between intraperitoneal and other routes of administration

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Pages 113-121 | Received 05 Jan 1987, Published online: 22 Sep 2008

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Prashant B. Nigade, Jayasagar Gundu, K. Sreedhara Pai, Kumar V. S. Nemmani & Rashmi Talwar. (2019) Prediction of volume of distribution in preclinical species and humans: application of simplified physiologically based algorithms. Xenobiotica 49:5, pages 528-539.
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R. N. Upton, C. Nancarrow, C. F. McLean, L. E. Mather & W. B. Runciman. (1991) The in vivo blood, fat and muscle concentrations of lignocaine and bupivacaine in the hindquarters of sheep. Xenobiotica 21:1, pages 13-22.
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Frederike Nordmeier, Adrian A Doerr, Stefan Potente, Nadja Walle, Matthias W Laschke, Michael D Menger, Peter H Schmidt, Markus R Meyer & Nadine Schaefer. (2022) Perimortem Distribution of U-47700, Tramadol and Their Main Metabolites in Pigs Following Intravenous Administration. Journal of Analytical Toxicology 46:5, pages 479-486.
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Andrew M. Brandon, Lysbeth H. Antonides, Jennifer Riley, Ola Epemolu, Denise A. McKeown, Kevin D. Read & Craig McKenzie. (2021) A Systematic Study of the In Vitro Pharmacokinetics and Estimated Human In Vivo Clearance of Indole and Indazole-3-Carboxamide Synthetic Cannabinoid Receptor Agonists Detected on the Illicit Drug Market. Molecules 26:5, pages 1396.
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Nadine Schaefer, Frederike Nordmeier, Ann-Katrin Kröll, Christina Körbel, Matthias W. Laschke, Michael D. Menger, Hans H. Maurer, Markus R. Meyer & Peter H. Schmidt. (2020) Is adipose tissue suitable for detection of (synthetic) cannabinoids? A comparative study analyzing antemortem and postmortem specimens following pulmonary administration of JWH-210, RCS-4, as well as ∆9-tetrahydrocannabinol to pigs. Archives of Toxicology 94:10, pages 3421-3431.
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Christian Carpéné, Francisco Les, Josep Mercader, Saioa Gomez-Zorita, Jean-Louis Grolleau, Nathalie Boulet, Jessica Fontaine, Mari Carmen Iglesias-Osma & Maria José Garcia-Barrado. (2020) Opipramol Inhibits Lipolysis in Human Adipocytes without Altering Glucose Uptake and Differently from Antipsychotic and Antidepressant Drugs with Adverse Effects on Body Weight Control. Pharmaceuticals 13:3, pages 41.
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Roi Rutenberg, Daria Galaktionova, Gilad Golden, Yael Cohen, Yael Levi-Kalisman, Guy Cohen, Petr Král & Elena Poverenov. (2018) Omniphilic Polysaccharide-Based Nanocarriers for Modular Molecular Delivery in a Broad Range of Biosystems. ACS Applied Materials & Interfaces 10:43, pages 36711-36720.
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Prashant B. Nigade, Jayasagar Gundu, K. Sreedhara Pai & Kumar V. S. Nemmani. (2017) Prediction of Tissue-to-Plasma Ratios of Basic Compounds in Mice. European Journal of Drug Metabolism and Pharmacokinetics 42:5, pages 835-847.
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Jongkil Kim, Kunho Chung, Changseon Choi, Jagadish Beloor, Irfan Ullah, Nahyeon Kim, Kuen Yong Lee, Sang-Kyung Lee & Priti Kumar. (2016) Silencing CCR2 in Macrophages Alleviates Adipose Tissue Inflammation and the Associated Metabolic Syndrome in Dietary Obese Mice. Molecular Therapy - Nucleic Acids 5, pages e280.
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S Minder, W A Daniel, J Clausen & M H Bickel. (1994) Adipose tissue storage of drugs as a function of binding competition. In-vitro studies with distribution dialysis. Journal of Pharmacy and Pharmacology 46:4, pages 313-315.
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J. E. Ruscoe, M. D. Tingle, P. M. O’Neill, S. A. Ward & B. K. Park. (1998) Effect of Disposition of Mannich Antimalarial Agents on Their Pharmacology and Toxicology. Antimicrobial Agents and Chemotherapy 42:9, pages 2410-2416.
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Joao B. T. Rocha, Jose E. T. Santos, Luis K. Rocha & Elcio R. Kleinpaul. (2009) Undernutrition During Suckling Changes the Sensitivity to Haloperidol and Chlorpromazine in Two Behavioural Measures in Weaning Rats. Pharmacology & Toxicology 81:3, pages 114-123.
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Christopher J Matheny, David R. Taft, Kim L.R. Brouwer & Gary M. Pollack. (1996) Evidence for reversible sequestration of morphine in rat liver. Biochemical Pharmacology 52:4, pages 535-541.
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M. J. Moor, S. H. Steiner, G. Jachertz & M. H. Bickel. (2009) Adipose Tissue Distribution and Chemical Structure of Basic Lipophilic Drugs: Desipramine, N‐Acetyl Desipramine, and Haloperidol. Pharmacology & Toxicology 70:2, pages 121-124.
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Richard N. Upton, William B. Runciman & Laurence E. Mather. (2006) Regional pharmacokinetics II. Experimental methods. Biopharmaceutics & Drug Disposition 11:9, pages 741-752.
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