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Xenobiotica
the fate of foreign compounds in biological systems
Volume 19, 1989 - Issue 2
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Original Article

Distribution and metabolism of 1,2,4-trimethylbenzene (pseudocumene) in the rat

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Pages 161-170 | Published online: 30 Sep 2009

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Richard H. Mckee, M. David Adenuga & Juan-Carlos Carrillo. (2015) Characterization of the toxicological hazards of hydrocarbon solvents. Critical Reviews in Toxicology 45:4, pages 273-365.
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Yasushi Yamazoe, Kazumi Ito & Kouichi Yoshinari. (2011) Construction of a CYP2E1-template system for prediction of the metabolism on both site and preference order. Drug Metabolism Reviews 43:4, pages 409-439.
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H. Moriwaki, Y. Tsujimoto, M. Shimizu, T. Noda, M. Warashina & M. Tanaka. (2005) Influence of sodium benzoate on the metabolism of o-xylene in the rat. Xenobiotica 35:5, pages 487-497.
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Articles from other publishers (16)

J. Allen Davis & Andrew Kraft. 2024. Encyclopedia of Toxicology. Encyclopedia of Toxicology 621 626 .
J. Allen Davis & Andrew Kraft. (2017) Quantitative meta-analytic approaches for the systematic synthesis of data and hazard identification: A case study of decreased pain sensitivity due to trimethylbenzene exposure. Environmental Research 158, pages 598-609.
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. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 27 .
David Adenuga, Juan-Carlos Carrillo & Richard H. Mckee. (2014) The sub-chronic oral toxicity of 1,3,5-trimethylbenzene in Sprague–Dawley rats. Regulatory Toxicology and Pharmacology 69:2, pages 143-153.
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. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 25 .
Toshiaki Yoshida. (2010) Estimation of absorption of aromatic hydrocarbons diffusing from interior materials in automobile cabins by inhalation toxicokinetic analysis in rats. Journal of Applied Toxicology 30:6, pages 525-535.
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Yuji Tsujimoto, Munehiro Warashina, Vu Duc Nam, Tsutomu Noda, Mitsuru Shimizu, Yukihiko Yamaguchi, Hiroshi Moriwaki, Tsumoru Morimoto, Kiyomi Kakiuchi, Yasuaki Maeda & Masanobu Tanaka. (2005) Determination of Urinary Phenolic Metabolites from Rats Treated with 1,2,3‐ and 1,3,5‐ Trimethylbenzenes. Journal of Occupational Health 47:4, pages 337-339.
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A.M. Saillenfait, F. Gallissot, J.P. Sabate & G. Morel. (2005) Developmental toxicity of two trimethylbenzene isomers, mesitylene and pseudocumene, in rats following inhalation exposure. Food and Chemical Toxicology 43:7, pages 1055-1063.
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Hiroshi Moriwaki, Ayumi Watanabe, Ryuichi Arakawa, Yuji Tsujimoto, Mitsuru Shimizu, Tsutomu Noda, Munehiro Warashina & Masanobu Tanaka. (2002) Simultaneous determination of metabolites of trimethylbenzenes, dimethylbenzylmercapturicacid and dimethylhippuric acid, in human urine by solid‐phase extraction followed by liquid chromatography tandem mass spectrometry. Journal of Mass Spectrometry 37:11, pages 1152-1157.
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Sławomir Gralewicz & Dorota Wiaderna. (2001) Behavioral Effects Following Subacute Inhalation Exposure to m-Xylene or Trimethylbenzene in the Rat. NeuroToxicology 22:1, pages 79-89.
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Yuji Tsujimoto, Tsutomu Noda, Mitsuru Shimizu, Hiroshi Moriwaki & Masanobu Tanaka. (2000) Identification of the dimethylbenzyl mercapturic acid in urine of rats administered with 1,2,4-trimethylbenzene. Chemosphere 40:8, pages 893-896.
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Yuji Tsujimoto, Tsutomu Noda, Mitsuru Shimizu, Hiroshi Moriwaki & Masanobu Tanaka. (1999) Identification of the dimethylbenzyl mercapturic acid in urine of rats treated with 1,2,3-trimethylbenzene. Chemosphere 39:5, pages 725-730.
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Yuji Tsujimoto, Tsutomu Noda, Mitsuru Shimizu, Hiroshi Moriwaki & Masanobu Tanaka. (1999) Synthesis of regioisomeric dimethylbenzyl mercapturic acids anticipated from the metabolism of 1,2,3-trimethylbenzene. Chemosphere 38:9, pages 2065-2070.
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Yukio Fukaya, Isao Saito, Tadao Matsumoto, Yasuhiro Takeuchi & Shinkan Tokudome. (1994) Determination of 3,4-dimethylhippuric acid as a biological monitoring index for trimethylbenzene exposure in transfer printing workers. International Archives of Occupational and Environmental Health 65:5, pages 295-297.
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Masayoshi Ichiba, Hidemi Hama, Shiro Yukitake, Masaki Kubota, Seiji Kawasaki & Katsumaro Tomokuni. (1992) Urinary excretion of 3,4-dimethylhippuric acid in workers exposed to 1,2,4-trimethylbenzene. International Archives of Occupational and Environmental Health 64:5, pages 325-327.
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Silvia Busini, Paolo Bavazzano & Ernesto Occhiato. (1992) High-performance liquid chromatographic determination of 3,5-dimethylhippuric acid in the occupational exposure to trimethylbenzenes. Journal of Chromatography B: Biomedical Sciences and Applications 577:1, pages 180-184.
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