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Xenobiotica
the fate of foreign compounds in biological systems
Volume 19, 1989 - Issue 2
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Original Article

Polymorphic ochratoxin A hydroxylation in rat strains phenotyped as poor and extensive metabolizers of debrisoquine

M. Castegnaro International Agency for Research on Cancer, 150 cours Albert Thomas, 69372, Lyon Cedex 08, France
,
H. Bartsch International Agency for Research on Cancer, 150 cours Albert Thomas, 69372, Lyon Cedex 08, France
,
J. C. Bereziat International Agency for Research on Cancer, 150 cours Albert Thomas, 69372, Lyon Cedex 08, France
,
P. Arvela Department of Pharmacology, University of Oulu, Finland
,
J. Michelon International Agency for Research on Cancer, 150 cours Albert Thomas, 69372, Lyon Cedex 08, France
&
L. Broussolle International Agency for Research on Cancer, 150 cours Albert Thomas, 69372, Lyon Cedex 08, France
Pages 225-230 | Received 10 May 1988, Accepted 21 Oct 1988, Published online: 30 Sep 2009

Citations (12)

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Read on this site (3)

P. Galtier. (1999) Biotransformation and Fate of Mycotoxins. Journal of Toxicology: Toxin Reviews 18:3-4, pages 295-312.
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E. E. Creppy. (1999) Human Ochratoxicosis. Journal of Toxicology: Toxin Reviews 18:3-4, pages 277-293.
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E. E. Creppy, I. Baudrimont, A. Belmadani & A-M Betbeder. (1996) Aspartame as a Preventive Agent of Chronic Toxic Effects of Ochratoxin a in Experimental Animals. Journal of Toxicology: Toxin Reviews 15:3, pages 207-221.
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Articles from other publishers (9)

Dieter Schrenk, Laurent Bodin, James Kevin Chipman, Jesús del Mazo, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Christiane Vleminckx, Heather Wallace, Jan Alexander, Chiara Dall'Asta, Angela Mally, Manfred Metzler, Marco Binaglia, Zsuzsanna Horváth, Hans Steinkellner & Margherita Bignami. (2020) Risk assessment of ochratoxin A in food. EFSA Journal 18:5.
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A. Vettorazzi, E. González-Peñas & A. López de Cerain. (2014) Ochratoxin A kinetics: A review of analytical methods and studies in rat model. Food and Chemical Toxicology 72, pages 273-288.
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Angela Mally. (2012) Ochratoxin A and Mitotic Disruption: Mode of Action Analysis of Renal Tumor Formation by Ochratoxin A. Toxicological Sciences 127:2, pages 315-330.
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Annie Pfohl-Leszkowicz & Richard A. Manderville. (2007) Ochratoxin A: An overview on toxicity and carcinogenicity in animals and humans. Molecular Nutrition & Food Research 51:1, pages 61-99.
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Richard A. Manderville & Annie Pfohl-Leszkowicz. 2006. 85 138 .
Herbert Zepnik, Wolfgang Völkel & Wolfgang Dekant. (2003) Toxicokinetics of the mycotoxin ochratoxin A in F 344 rats after oral administration. Toxicology and Applied Pharmacology 192:1, pages 36-44.
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Woo-Chan Son, Kenji Kamino, Yong-Soon Lee & Kyung-Sun Kang. (2003) Lack of effects of sodium 2-mercaptoethane sulfonate (mesna) on Ochratoxin A induced renal tumorigenicity following life-time oral administration of Ochratoxin A in DA and Lewis rats. Toxicology Letters 142:1-2, pages 19-27.
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Marcel Castegnaro, Ulrich Mohr, Annie Pfohl-Leszkowicz, Jacques Estève, Jurgen Steinmann, Thomas Tillmann, Jocelyne Michelon & Helmut Bartsch. (1998) Sex- and strain-specific induction of renal tumors by ochratoxin A in rats correlates with DNA adduction. International Journal of Cancer 77:1, pages 70-75.
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Thierry Oster, Zaid Jayyosi, Edmond E. Creppy, Hajar Souhaili El Amri & Anne-Marie Batt. (1991) Characterization of pig liver purified cytochrome P-450 isoenzymes for ochratoxin a metabolism studies. Toxicology Letters 57:2, pages 203-214.
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