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Xenobiotica
the fate of foreign compounds in biological systems
Volume 19, 1989 - Issue 4
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Research Article

Zonal Distribution of Paracetamol Glucuronidation in the Isolated Perfused Rat Liver

Mack C. Mitchell Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205, USA
,
Reta Hamilton Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
,
Laura Wacker Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205, USA
&
Robert A. Branch Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Pages 389-400 | Received 21 Apr 1988, Accepted 10 Nov 1988, Published online: 22 Sep 2008

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Jos G. M. Bessems & Nico P. E. Vermeulen. (2001) Paracetamol (Acetaminophen)-Induced Toxicity: Molecular and Biochemical Mechanisms, Analogues and Protective Approaches. Critical Reviews in Toxicology 31:1, pages 55-138.
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CiaranF. Duffy, DeclanP. Bogan & Richard O'Kennedy. (1997) Determination by HPLC of the UDP-Glucuronyl Transferase Activity For 7-Hydroxycoumarin in Rabbit Tissue Samples. Journal of Liquid Chromatography & Related Technologies 20:2, pages 217-226.
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Articles from other publishers (9)

Declan P Bogan, Ciaran F Duffy & Richard O'Kennedy. (1997) In vitro glucuronidation of 7-hydroxycoumarin and determination of 7-hydroxycoumarin and 7-hydroxycoumarin glucuronide by capillary electrophoresis. Journal of Chromatography A 772:1-2, pages 321-326.
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B. R. LandauC. A. FernandezS. F. PrevisK. EkbergV. ChandramouliJ. WahrenS. C. KalhanH. Brunengraber. (1995) A limitation in the use of mass isotopomer distributions to measure gluconeogenesis in fasting humans. American Journal of Physiology-Endocrinology and Metabolism 269:1, pages E18-E26.
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Andreas Langner. (2006) Ersatz‐ und Ergänzungsmethoden zur Untersuchung der Biotransformation von Arzneistoffen. Pharmazie in unserer Zeit 24:4, pages 207-218.
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Serge Dionne, Beatriz Tuchweber, Gabriel L. Plaa & Ibrahim M. Yousef. (1994) Phase I and phase II metabolism of lithocholic acid in hepatic acinar zone 3 necrosis. Biochemical Pharmacology 48:6, pages 1187-1197.
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D. J. Clarke & B. Burchell. 1994. Conjugation—Deconjugation Reactions in Drug Metabolism and Toxicity. Conjugation—Deconjugation Reactions in Drug Metabolism and Toxicity 3 43 .
Susan L. Elliott, Denis J. Morgan, Peter W. Angus, Hany Ghabrial, R.G.Peter Watson & Richard A. Smallwood. (1993) The effect of hypoxia on propranolol clearance during antegrade and retrograde flow in the isolated perfused rat liver preparation. Biochemical Pharmacology 45:3, pages 573-578.
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Rolf Gebhardt. (1992) Metabolic zonation of the liver: Regulation and implications for liver function. Pharmacology & Therapeutics 53:3, pages 275-354.
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Anastacio M. Hoyumpa & Steven Schenker. (1991) Is glucuronidation truly preserved in patients with liver disease?. Hepatology 13:4, pages 786-795.
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Steven Schenker & Anastacio M. Hoyumpa. 1991. Cirrhosis, Hepatic Encephalopathy, and Ammonium Toxicity. Cirrhosis, Hepatic Encephalopathy, and Ammonium Toxicity 209 226 .

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