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Xenobiotica
the fate of foreign compounds in biological systems
Volume 19, 1989 - Issue 4
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Research Article

Comparison of Caffeine Metabolism by Slices, Microsomes and Hepatocyte Cultures from Adult Human Liver

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Pages 401-417 | Received 02 Jun 1988, Accepted 24 Nov 1988, Published online: 22 Sep 2008

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Chukwunonso K. Nwabufo, Omozojie P. Aigbogun, Kevin J.H Allen, Madeline N. Owens, Jeremy S. Lee, Christopher P. Phenix & Ed S. Krol. (2021) Employing in vitro metabolism to guide design of F-labelled PET probes of novel α-synuclein binding bifunctional compounds. Xenobiotica 51:8, pages 885-900.
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S. E. CLARKE. (1998) In vitro assessment of human cytochrome P450. Xenobiotica 28:12, pages 1167-1202.
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Michael L. Gargas, Michele A. Medinsky & Melvin E. Andersen. (1995) Pharmacokinetic Modeling Approaches for Describing the Uptake, Systemic Distribution, and Disposition of Inhaled Chemicals. Critical Reviews in Toxicology 25:3, pages 237-254.
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J. C. Bloomer, S. E. Clarke & R. J. Chenery. (1995) Determination of P4501A2 activity in human liver microsomes using [3-14C-methyl]caffeine. Xenobiotica 25:9, pages 917-927.
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N. Rodopoulos, O. Wisen & A. Norman. (1995) Caffeine metabolism in patients with chronic liver disease. Scandinavian Journal of Clinical and Laboratory Investigation 55:3, pages 229-242.
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Steven A. Wrighton, Mark Vandenbranden, Jeffrey C. Stevens, Lisa A. Shipley, Barbara J. Ring, John R. Cashman & Allan E. Rettie. (1993) In Vitro Methods for Assessing Human Hepatic Drug Metabolism: Their use in Drug Development. Drug Metabolism Reviews 25:4, pages 453-484.
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F. Berthou, B. Guillois, C. Riche, Y. Dreano, E. Jacqz-Aigrain & P. H. Beaune. (1992) Interspecies variations in caffeine metabolism related to cytochrome P4501A enzymes. Xenobiotica 22:6, pages 671-680.
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