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Xenobiotica
the fate of foreign compounds in biological systems
Volume 19, 1989 - Issue 5
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Research Article

Optimization of Cryopreservation Procedures for Rat and Human Hepatocytes

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Pages 489-498 | Received 14 Jul 1988, Accepted 10 Jan 1989, Published online: 22 Sep 2008

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Eliane Alexandre, Audrey Baze, Céline Parmentier, Coraline Desbans, Dumrongsak Pekthong, Brigitte Gerin, Claudine Wack, Philippe Bachellier, Bruno Heyd, Jean-Christophe Weber & Lysiane Richert. (2012) Plateable cryopreserved human hepatocytes for the assessment of cytochrome P450 inducibility: experimental condition-related variables affecting their response to inducers. Xenobiotica 42:10, pages 968-979.
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M. J. Gómez-Lechón, A. Lahoz, N. Jiménez, J. Vicente Castell & M. T. Donato. (2006) Cryopreservation of rat, dog and human hepatocytes: influence of preculture and cryoprotectants on recovery, cytochrome P450 activities and induction upon thawing. Xenobiotica 36:6, pages 457-472.
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Jos V Castell, Ramiro Jover, Celia P Martnez-Jimnez & Mara Jos Gmez-Lechn. (2006) Hepatocyte cell lines: their use, scope and limitations in drug metabolism studies. Expert Opinion on Drug Metabolism & Toxicology 2:2, pages 183-212.
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D. M. CROSS & M. K. BAYLISS. (2000) A COMMENTARY ON THE USE OF HEPATOCYTES IN DRUG METABOLISM STUDIES DURING DRUG DISCOVERY AND DEVELOPMENT*. Drug Metabolism Reviews 32:2, pages 219-240.
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P. OLINGA, M. T. MEREMA, I. H. HOF, M. H. DE JAGER, K. P. DE JONG, M. J. H. SLOOFF, D. K. F. MEIJER & G. M. M. GROOTHUIS. (1998) Effect of cold and warm ischaemia on drug metabolism in isolated hepatocytes and slices from human and monkey liver. Xenobiotica 28:4, pages 349-360.
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Steven A. Wrighton, Mark Vandenbranden, Jeffrey C. Stevens, Lisa A. Shipley, Barbara J. Ring, John R. Cashman & Allan E. Rettie. (1993) In Vitro Methods for Assessing Human Hepatic Drug Metabolism: Their use in Drug Development. Drug Metabolism Reviews 25:4, pages 453-484.
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J. A. Coundouris, M. H. Grant, J. Engeset, J. C. Petrie & G. M. Hawksworth. (1993) Cryopreservation of human adult hepatocytes for use in drug metabolism and toxicity studies. Xenobiotica 23:12, pages 1399-1409.
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