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Xenobiotica
the fate of foreign compounds in biological systems
Volume 19, 1989 - Issue 7
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Research Article

Effects of Methyl Ethyl Ketone Pretreatment on Hepatic Mixed-Function Oxidase Activity and on in Vivo Metabolism of N-Hexane

P. Robertson Department of General and Biochemical Toxicology, Chemical Industry Institute of Toxicology, PO Box 12137, Research Triangle Park, NC, 27709, USA
,
E. L. White Department of General and Biochemical Toxicology, Chemical Industry Institute of Toxicology, PO Box 12137, Research Triangle Park, NC, 27709, USA
&
J. S. Bus Department of General and Biochemical Toxicology, Chemical Industry Institute of Toxicology, PO Box 12137, Research Triangle Park, NC, 27709, USA
Pages 721-729 | Received 21 Sep 1988, Accepted 10 Feb 1989, Published online: 22 Sep 2008

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Frédéric Cosnier, Stéphane Grossmann, Hervé Nunge, Céline Brochard, Samuel Muller, Anne-Marie Lambert-Xolin, Sylvie Sebillaud, Benoît Rieger, Aurélie Thomas, Marie-Josèphe Décret, Manuella Burgart, Laurent Gaté, Benoît Cossec & Pierre Campo. (2018) Metabolism of inhaled methylethylketone in rats. Drug and Chemical Toxicology 41:1, pages 42-50.
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Y. Zhang, Q. Liu, Q. Liu, H. Duan, J. Cheng, S. Jiang, X. Huang, S. Leng, F. He & Y. Zheng. (2006) Association between metabolic gene polymorphisms and susceptibility to peripheral nerve damage in workers exposed to n-hexane: A preliminary study. Biomarkers 11:1, pages 61-69.
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Agneta Löf & Gunnar Johanson. (1998) Toxicokinetics of Organic Solvents: A Review of Modifying Factors. Critical Reviews in Toxicology 28:6, pages 571-650.
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Doyle G. Graham, Venkataraman Amarnath, William M. Valentine, Sally J. Pyle & Douglas C. Anthony. (1995) Pathogenetic Studies of Hexane and Carbon Disulfide Neurotoxicity. Critical Reviews in Toxicology 25:2, pages 91-112.
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J. Liira, E. Elovaara, H. Raunio, V. Riihimäki & K. Engström. (1991) Metabolic interaction and disposition of methyl ethyl ketone and m-xylene in rats at single and repeated inhalation exposures. Xenobiotica 21:1, pages 53-63.
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Articles from other publishers (10)

John L. O'Donoghue. 2003. Patty's Toxicology. Patty's Toxicology 1 56 .
Shuo Wang, Ming Li, Xujing Wang, Xianjie Li, Hongyin Yin, Lulu Jiang, Wenting Han, Gleniece Irving, Tao Zeng & Keqin Xie. (2017) Diallyl trisulfide attenuated n-hexane induced neurotoxicity in rats by modulating P450 enzymes. Chemico-Biological Interactions 265, pages 1-7.
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John L. O'Donoghue. 2003. Patty's Toxicology. Patty's Toxicology 753 806 .
W. Huckenbeck & W. Bonte. 2003. Handbuch gerichtliche Medizin 2. Handbuch gerichtliche Medizin 2 379 636 .
David A. Morgott, Douglas C. Topping & John L. O'Donoghue. 2003. Patty's Toxicology. Patty's Toxicology.
David A. Morgott. 2003. Patty's Toxicology. Patty's Toxicology.
Bjarte Mortensen, Kolbjørn Zahlsen & Odd G. Nilsen. (2009) Metabolic Interaction of n ‐Hexane and Methyl Ethyl Ketone in vitro in a Head Space Rat Liver S9 Vial Equilibration System . Pharmacology & Toxicology 82:2, pages 67-71.
Crossref
Kazuo Aoki, Wenyuan Zhao, Junichi Misumi, Takato Yasui & Masanobu Kudo. (2006) Changes in 2,5‐Hexanedione Concentration in the Sciatic Nerve, Serum and Urine of Rats Induced by Combined Administration of 2,5‐Hexanedione with Acetone or Methyl Ethyl Ketone. Journal of Occupational Health 38:1, pages 30-35.
Crossref
G. J. A. Speijers. 1993. Chemistry and Analysis of Volatile Organic Compounds in the Environment. Chemistry and Analysis of Volatile Organic Compounds in the Environment 25 91 .
Marek Jakubowski. 1993. Use of Biomarkers in Assessing Health and Environmental Impacts of Chemical Pollutants. Use of Biomarkers in Assessing Health and Environmental Impacts of Chemical Pollutants 83 94 .

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